{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T03:27:52Z","timestamp":1789615672889,"version":"build-2803163510"},"reference-count":58,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,3,28]],"date-time":"2020-03-28T00:00:00Z","timestamp":1585353600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31871677"],"award-info":[{"award-number":["31871677"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Key R&amp;D Program of China","award":["2017YFD0101600"],"award-info":[{"award-number":["2017YFD0101600"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genes"],"abstract":"<jats:p>Cotton possesses certain physical features, including leaf and stem trichomes that help plants deter damage caused by insect pests, and to some extent, from abiotic factors as well. Among those features, trichomes (pubescence) hold a special place as a first line of defense and a managemental tool against sucking insect pests of cotton. Different insect pests of cotton (whiteflies, aphids, jassids, and boll weevil) severely damage the yield and quality of the crop. Likewise, whiteflies, aphids, jassids, and other insect pests are considered as potential carriers for cotton leaf curl viruses and other diseases. Genotyping by sequencing (GBS) study was conducted to understand and explore the genomic regions governing hairy (Pubescence) leaves and stem phenotypes. A total of 224 individuals developed from an intraspecific cross (densely haired cotton (Liaoyang duomao mian) \u00d7 hairless cotton (Zong 128)) and characterized phenotypically for leaf and stem pubescence in different environments. Here we identify and report significant QTLs (quantitative trait loci) associated with leaf and stem pubescence, and the response of plant under pest (aphid) infestation. Further, we identified putative genes colocalized on chromosome A06 governing mechanism for trichome development and host\u2013pest interaction. Our study provides a comprehensive insight into genetic architecture that can be employed to improve molecular marker-assisted breeding programs aimed at developing biotic (insect pests) resilient cotton cultivars.<\/jats:p>","DOI":"10.3390\/genes11040368","type":"journal-article","created":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T05:52:30Z","timestamp":1585720350000},"page":"368","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Genotyping by Sequencing Revealed QTL Hotspots for Trichome-Based Plant Defense in Gossypium hirsutum"],"prefix":"10.3390","volume":"11","author":[{"given":"Haris","family":"Ahmed","sequence":"first","affiliation":[{"name":"Institute of Cotton Research, Chinese Academy of Agricultural Sciences, State Key Laboratory of Cotton Biology, Anyang, Henan 455000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7097-181X","authenticated-orcid":false,"given":"Mian Faisal","family":"Nazir","sequence":"additional","affiliation":[{"name":"Institute of Cotton Research, Chinese Academy of Agricultural Sciences, State Key Laboratory of Cotton Biology, Anyang, Henan 455000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhoe","family":"Pan","sequence":"additional","affiliation":[{"name":"Institute of Cotton Research, Chinese Academy of Agricultural Sciences, State Key Laboratory of Cotton Biology, Anyang, Henan 455000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenfang","family":"Gong","sequence":"additional","affiliation":[{"name":"Key Laboratory of Cultivation and Protection for Non-Wood Forest Trees, Ministry of Education, Central South University of Forestry and Technology, Changsha 410004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5458-1179","authenticated-orcid":false,"given":"Muhammad Shahid","family":"Iqbal","sequence":"additional","affiliation":[{"name":"Institute of Cotton Research, Chinese Academy of Agricultural Sciences, State Key Laboratory of Cotton Biology, Anyang, Henan 455000, China"},{"name":"Cotton Research Station, Ayub Agriculture Research Institute, Faisalabad 38000, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoupu","family":"He","sequence":"additional","affiliation":[{"name":"Institute of Cotton Research, Chinese Academy of Agricultural Sciences, State Key Laboratory of Cotton Biology, Anyang, Henan 455000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiongming","family":"Du","sequence":"additional","affiliation":[{"name":"Institute of Cotton Research, Chinese Academy of Agricultural Sciences, State Key Laboratory of Cotton Biology, Anyang, Henan 455000, China"},{"name":"Zhengzhou Research Base, State Key Laboratory of Cotton Biology, Zhengzhou University, Zhengzhou 450001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,3,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1534\/genetics.115.178236","article-title":"The hairless stem phenotype of cotton (Gossypium barbadense) is linked to a copia-like retrotransposon insertion in a homeodomain-leucine zipper gene (HD1)","volume":"201","author":"Ding","year":"2015","journal-title":"Genetics"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1093\/jee\/90.4.1046","article-title":"Preference of Gossypium genotypes to bemisia argentifolii (Homoptera: Aleyrodidae)","volume":"90","author":"Meagher","year":"1997","journal-title":"J. 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