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The most active countries and the most impactful documents in the field were identified. Furthermore, a total of 13 main thematic clusters emerged in the literature. From the qualitative inspection of clusters, it emerged that the research interest moved from a monogenic to a polygenic risk framework. Researchers have moved from the study of single genes in the early 1990s to conducting genome-wide association studies around 2015. In this way, genetic overlaps between mood disorders and other psychiatric conditions emerged too. Furthermore, around the 2010s, the interaction between genes and environmental factors emerged as pivotal in understanding the risk for mood disorders. The inspection of thematic clusters provides a valuable insight into the past and recent trends of research in the genetics of mood disorders and sheds light onto future lines of research.<\/jats:p>","DOI":"10.3390\/genes14020352","type":"journal-article","created":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T06:06:13Z","timestamp":1675058773000},"page":"352","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The Genetic Side of the Mood: A Scientometric Review of the Genetic Basis of Mood Disorders"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1608-4272","authenticated-orcid":false,"given":"Giovanni","family":"Bonacina","sequence":"first","affiliation":[{"name":"Department of Psychology and Cognitive Science, University of Trento, Corso Angelo Bettini 31, 38068 Rovereto, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2737-0218","authenticated-orcid":false,"given":"Alessandro","family":"Carollo","sequence":"additional","affiliation":[{"name":"Department of Psychology and Cognitive Science, University of Trento, Corso Angelo Bettini 31, 38068 Rovereto, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9442-0254","authenticated-orcid":false,"given":"Gianluca","family":"Esposito","sequence":"additional","affiliation":[{"name":"Department of Psychology and Cognitive Science, University of Trento, Corso Angelo Bettini 31, 38068 Rovereto, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,30]]},"reference":[{"key":"ref_1","unstructured":"Butcher, J.N., Hooley, J.M., Nock, M.K., and Mineka, S. 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