{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T19:20:17Z","timestamp":1778700017803,"version":"3.51.4"},"reference-count":91,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T00:00:00Z","timestamp":1692835200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"S\u00e3o Paulo State Research Foundation","award":["2018\/25437-6"],"award-info":[{"award-number":["2018\/25437-6"]}]},{"name":"S\u00e3o Paulo State Research Foundation","award":["2018\/18751-6"],"award-info":[{"award-number":["2018\/18751-6"]}]},{"name":"S\u00e3o Paulo State Research Foundation","award":["2017\/23127-7"],"award-info":[{"award-number":["2017\/23127-7"]}]},{"name":"S\u00e3o Paulo State Research Foundation","award":["CNPq 301865\/2018-3"],"award-info":[{"award-number":["CNPq 301865\/2018-3"]}]},{"name":"Brazilian National Council for Scientific and Technological Development","award":["2018\/25437-6"],"award-info":[{"award-number":["2018\/25437-6"]}]},{"name":"Brazilian National Council for Scientific and Technological Development","award":["2018\/18751-6"],"award-info":[{"award-number":["2018\/18751-6"]}]},{"name":"Brazilian National Council for Scientific and Technological Development","award":["2017\/23127-7"],"award-info":[{"award-number":["2017\/23127-7"]}]},{"name":"Brazilian National Council for Scientific and Technological Development","award":["CNPq 301865\/2018-3"],"award-info":[{"award-number":["CNPq 301865\/2018-3"]}]},{"name":"Superintendency for Endemic Disease Control (SUCEN) at the S\u00e3o Paulo State Health Department","award":["2018\/25437-6"],"award-info":[{"award-number":["2018\/25437-6"]}]},{"name":"Superintendency for Endemic Disease Control (SUCEN) at the S\u00e3o Paulo State Health Department","award":["2018\/18751-6"],"award-info":[{"award-number":["2018\/18751-6"]}]},{"name":"Superintendency for Endemic Disease Control (SUCEN) at the S\u00e3o Paulo State Health Department","award":["2017\/23127-7"],"award-info":[{"award-number":["2017\/23127-7"]}]},{"name":"Superintendency for Endemic Disease Control (SUCEN) at the S\u00e3o Paulo State Health Department","award":["CNPq 301865\/2018-3"],"award-info":[{"award-number":["CNPq 301865\/2018-3"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genes"],"abstract":"<jats:p>Genetic diversity and population structuring for the species Haemogogus leucocelaenus, a sylvatic vector of yellow fever virus, were found to vary with the degree of agricultural land use and isolation of fragments of Atlantic Forest in municipalities in the state of S\u00e3o Paulo where specimens were collected. Genotyping of 115 mitochondrial SNPs showed that the populations with the highest indices of genetic diversity (polymorphic loci and mean pairwise differences between the sequences) are found in areas with high levels of agricultural land use (northeast of the State). Most populations exhibited statistically significant negative values for the Tajima D and Fu FS neutrality tests, suggesting recent expansion. The results show an association between genetic diversity in this species and the degree of agricultural land use in the sampled sites, as well as signs of population expansion of this species in most areas, particularly those with the highest forest edge densities. A clear association between population structuring and the distance between the sampled fragments (isolation by distance) was observed: samples from a large fragment of Atlantic Forest extending along the coast of the state of S\u00e3o Paulo exhibited greater similarity with each other than with populations in the northwest of the state.<\/jats:p>","DOI":"10.3390\/genes14091671","type":"journal-article","created":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T10:09:53Z","timestamp":1692871793000},"page":"1671","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Genetic Structuring of One of the Main Vectors of Sylvatic Yellow Fever: Haemagogus (Conopostegus) leucocelaenus (Diptera: Culicidae)"],"prefix":"10.3390","volume":"14","author":[{"given":"Ramon","family":"Wilk-da-Silva","sequence":"first","affiliation":[{"name":"Institute of Tropical Medicine, University of S\u00e3o Paulo, S\u00e3o Paulo 05403-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9493-8731","authenticated-orcid":false,"given":"Ant\u00f4nio Ralph","family":"Medeiros-Sousa","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Public Health, University of S\u00e3o Paulo, S\u00e3o Paulo 01246-904, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7766-7597","authenticated-orcid":false,"given":"Luis Filipe","family":"Mucci","sequence":"additional","affiliation":[{"name":"State Department of Health, Pasteur Institute, S\u00e3o Paulo 01027-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4992-6253","authenticated-orcid":false,"given":"Diego Peres","family":"Alonso","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Public Health, University of S\u00e3o Paulo, S\u00e3o Paulo 01246-904, Brazil"},{"name":"UNESP\u2014Biotechnology Institute and Biosciences Institute, Sao Paulo State University, Botucatu 18618-689, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7104-3954","authenticated-orcid":false,"given":"Marcus Vinicius Niz","family":"Alvarez","sequence":"additional","affiliation":[{"name":"UNESP\u2014Biotechnology Institute and Biosciences Institute, Sao Paulo State University, Botucatu 18618-689, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8735-6090","authenticated-orcid":false,"given":"Paulo Eduardo Martins","family":"Ribolla","sequence":"additional","affiliation":[{"name":"UNESP\u2014Biotechnology Institute and Biosciences Institute, Sao Paulo State University, Botucatu 18618-689, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0312-8777","authenticated-orcid":false,"given":"Mauro Toledo","family":"Marrelli","sequence":"additional","affiliation":[{"name":"Institute of Tropical Medicine, University of S\u00e3o Paulo, S\u00e3o Paulo 05403-000, Brazil"},{"name":"Department of Epidemiology, School of Public Health, University of S\u00e3o Paulo, S\u00e3o Paulo 01246-904, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,24]]},"reference":[{"key":"ref_1","unstructured":"Reed, S.C., Reibold, R., Cavaleri, M.A., Alonso-Rodr\u00edguez, A.M., Berberich, M.E., and Wood, T.E. 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