{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T22:27:33Z","timestamp":1792016853905,"version":"4.4.0"},"reference-count":66,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T00:00:00Z","timestamp":1742774400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genes"],"abstract":"<jats:p>Neuropsychiatric disorders are complex conditions with multifactorial etiologies, in which genetics play a pivotal role. Despite significant advancements in psychiatric research, traditional treatment options remain largely symptomatic, focusing on clinical signs without fully addressing the underlying biological causes. However, recent developments in precision medicine\u2014an approach that tailors treatments based on genetic, environmental, and lifestyle factors\u2014hold great promise for transforming the treatment of these disorders. By identifying specific genetic markers and understanding gene\u2013environment interactions, precision medicine can offer more personalized and effective treatments, leading to better patient outcomes. Our primary aim was to explore how integrating genetic data with environmental factors could enhance the understanding and treatment of neuropsychiatric conditions such as schizophrenia, bipolar disorder, and depression. The secondary aim was to examine the potential of pharmacogenomics and gene therapy in improving therapeutic strategies. The results indicate that while significant progress has been made, challenges remain, including the complexity of genetic interactions and the need for more granular phenotypic data. In conclusion, precision medicine has the potential to revolutionize neuropsychiatric treatment by providing individualized care that considers genetic makeup, environmental influences, and lifestyle factors, paving the way for more effective therapies and improved patient outcomes.<\/jats:p>","DOI":"10.3390\/genes16040371","type":"journal-article","created":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T13:48:20Z","timestamp":1742824100000},"page":"371","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Exploring the Potential of Precision Medicine in Neuropsychiatry: A Commentary on New Insights for Tailored Treatments Based on Genetic, Environmental, and Lifestyle Factors"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3596-5908","authenticated-orcid":false,"given":"Jelena","family":"Milic","sequence":"first","affiliation":[{"name":"Institute of Public Health of Serbia \u201cDr Milan Jovanovi\u0107 Batut\u201d, 11000 Belgrade, Serbia"},{"name":"European Faculty \u201cKallos\u201d, Ratariski Put 8a, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milica","family":"Vucurovic","sequence":"additional","affiliation":[{"name":"Institute of Public Health of Serbia \u201cDr Milan Jovanovi\u0107 Batut\u201d, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dragana","family":"Jovic","sequence":"additional","affiliation":[{"name":"Institute of Public Health of Serbia \u201cDr Milan Jovanovi\u0107 Batut\u201d, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veroslava","family":"Stankovic","sequence":"additional","affiliation":[{"name":"The College of Health Science, Academy of Applied Studies, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edita","family":"Grego","sequence":"additional","affiliation":[{"name":"Institute of Public Health of Serbia \u201cDr Milan Jovanovi\u0107 Batut\u201d, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srdja","family":"Jankovic","sequence":"additional","affiliation":[{"name":"The University Children\u2019s Hospital, 11000 Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7459-3353","authenticated-orcid":false,"given":"Rosa","family":"Sapic","sequence":"additional","affiliation":[{"name":"Faculty of Health Studies, University of Bjeljina, 76300 Bjeljina, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"B\u00fcki, G., Hadzsiev, K., and Bene, J. 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