{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:22:27Z","timestamp":1760059347458,"version":"build-2065373602"},"reference-count":48,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T00:00:00Z","timestamp":1749254400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"JSPS KAKENHI","award":["JP21K17419"],"award-info":[{"award-number":["JP21K17419"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geriatrics"],"abstract":"<jats:p>Background: Falls in older adults are a major barrier to healthy longevity. Recent studies suggest that muscle quality is associated with fall risk. This study aimed to determine whether a functional muscle quality index (MQI) using the 5-repetition sit-to-stand test (5R-STS) reflects fall risk in community-dwelling older adults. Methods: This cross-sectional study included 137 community-dwelling older adults (\u226565 years) in Japan. Lower limb skeletal muscle mass (SMM) was measured using the BIA method, and muscle function was assessed using the 5R-STS. The MQI was calculated as \u201c(5R-STS (s)\/SMM (kg)) \u00d7 10\u201d. Fall history was collected using a self-administered questionnaire, and binary logistic regression analysis including gait speed and physical frailty was performed. Results: Participants were divided into fallers (n = 36; age = 78.2 \u00b1 5.6) and non-fallers (n = 101; age = 76.9 \u00b1 5.3). Significant differences were found between the groups in gait speed (p = 0.01), TUG (p &lt; 0.01), 5R-STS (p &lt; 0.01), and MQI (p &lt; 0.01). Binary logistic regression identified MQI (OR = 1.28; p &lt; 0.01) and gait speed (OR = 0.14; p = 0.02) as explanatory variables for fall history. The results of the evaluation using the receiver operating characteristic (ROC) curve showed that the cutoff value for MQI to distinguish fall history was 8.04 s\/kg, and the cutoff value for gait speed was 1.21 s. Conclusions: The MQI using the 5R-STS shows promise as an indicator of fall risk in older adults. Further longitudinal studies are needed to clarify the causal relationship.<\/jats:p>","DOI":"10.3390\/geriatrics10030078","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T08:22:34Z","timestamp":1749457354000},"page":"78","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association Between Muscle Quality Assessed by the 5-Repetition Sit-to-Stand Test and Falls in Community-Dwelling Older Adults in Japan: A Cross-Sectional Study"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9998-7978","authenticated-orcid":false,"given":"Koji","family":"Takimoto","sequence":"first","affiliation":[{"name":"Department of Rehabilitation, Faculty of Health Sciences, Naragakuen University, 3-15-1 Nakatomigaoka, Nara 631-8524, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0222-0026","authenticated-orcid":false,"given":"Hideaki","family":"Takebayashi","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Faculty of Health Sciences, University of Kochi Health Sciences, 2500-2 Otsu, Kochi 781-5103, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Faculty of Health Sciences, University of Kochi Health Sciences, 2500-2 Otsu, Kochi 781-5103, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Faculty of Health Sciences, Naragakuen University, 3-15-1 Nakatomigaoka, Nara 631-8524, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1186\/s13018-022-03222-1","article-title":"Global Prevalence of Falls in the Older Adults: A Comprehensive Systematic Review and Meta-Analysis","volume":"17","author":"Salari","year":"2022","journal-title":"J. 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