{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T11:00:41Z","timestamp":1772276441165,"version":"3.50.1"},"reference-count":29,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T00:00:00Z","timestamp":1633910400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infectious Disease Reports"],"abstract":"<jats:p>In response to the raging COVID-19 pandemic, Bangladesh started its vaccine administration in early 2021; however, due to the rapid development and launch of the vaccines in the market, many people had concerns regarding the safety of these vaccines. The purpose of this study was to evaluate the side effects that were experienced by the Bangladeshi residents after receiving the first dose of the Oxford-AstraZeneca\u2019s Covishield vaccine (ChAdOx1nCoV-19). The study was conducted using both online and printed questionnaires and the data were analysed using SPSS. The results included the responses of 474 vaccine recipients from March\u2013April 2021. Pain at the site of injection, fever, myalgia, fatigue and headache were the most commonly reported symptoms, and the overall side effects were found to be significantly more prevalent in the younger population (p \u2264 0.05). These findings were consistent with the results indicated by the clinical trial of ChAdOx1nCoV-19. Logistic regression analysis further revealed that compared to people aged 70 years or above, the incidence of reported side effects was significantly higher in people aged 18\u201330 years (odds ratio (OR) = 8.56), 31\u201340 years, (OR = 5.05), 41\u201350 years (OR = 4.08), 51\u201360 years (OR = 3.77) and 61\u201370 years (OR = 3.67). In addition, a significantly higher percentage of female participants suffered from post-vaccination side effects compared to males (OR = 1.51). It was concluded that the Covishield vaccine was well-tolerated among people of different age groups. Nevertheless, further long-term follow-up study with a larger sample size is warranted to establish the long-term safety of the COVID-19 vaccine.<\/jats:p>","DOI":"10.3390\/idr13040080","type":"journal-article","created":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T21:47:34Z","timestamp":1633988854000},"page":"888-901","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Side Effects Following Administration of the First Dose of Oxford-AstraZeneca\u2019s Covishield Vaccine in Bangladesh: A Cross-Sectional Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3833-5346","authenticated-orcid":false,"given":"Nishat","family":"Jahan","sequence":"first","affiliation":[{"name":"Department of Pharmacy, University of Asia Pacific, Green Road, Dhaka 1205, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fahad Imtiaz","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0338-587X","authenticated-orcid":false,"given":"Poushali","family":"Saha","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadia Afruz","family":"Ether","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ASM","family":"Roknuzzaman","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Asia Pacific, Green Road, Dhaka 1205, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rapty","family":"Sarker","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Asia Pacific, Green Road, Dhaka 1205, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khondoker Tashya","family":"Kalam","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Asia Pacific, Green Road, Dhaka 1205, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kashfa","family":"Haq","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Asia Pacific, Green Road, Dhaka 1205, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julkar","family":"Nyeen","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Asia Pacific, Green Road, Dhaka 1205, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Humayra Zaman","family":"Himi","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Asia Pacific, Green Road, Dhaka 1205, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1349-0419","authenticated-orcid":false,"given":"Md. Nazmul","family":"Hossain","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Asia Pacific, Green Road, Dhaka 1205, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahtab Hossain","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University of Asia Pacific, Green Road, Dhaka 1205, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mostafa Moin","family":"Uddin","sequence":"additional","affiliation":[{"name":"Office of the Director General, Directorate General of Health Services (DGHS), Mohakhali, Dhaka 1212, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nur Haque","family":"Alam","sequence":"additional","affiliation":[{"name":"Nutrition and Clinical Services Division (NCSD), International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Mohakhali, Dhaka 1000, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ijsu.2020.02.034","article-title":"World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19)","volume":"76","author":"Sohrabi","year":"2020","journal-title":"Int. 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