{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T03:39:42Z","timestamp":1789616382505,"version":"build-2803163510"},"reference-count":13,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infectious Disease Reports"],"abstract":"<jats:p>Background: Since the outbreak of monkeypox in formerly non-endemic countries, we have included a screening for monkeypox in our sexually transmitted diseases (STD) routine in patients with high-risk behavior, as it is mainly transmitted through close skin to mucous membrane contact with infected individuals. Methods: Between 16 June 2022 and 14 July 2022, we screened 53 MSM with high-risk behavior for monkeypox acquisition in an observational prospective cohort trial. We complemented the throat and anal swabs for chlamydia and gonococci with monkeypox using polymerase chain reaction (PCR). In addition, all patients participated in a questionnaire survey about their risk behavior and previous STD in their medical history. Results: None of the 53 participants had tested positive for the monkeypox virus. One patient was diagnosed with syphilis and one with an oral and anorectal chlamydia infection. Conclusions: STD screening in high-risk populations is a valuable tool to detect asymptomatic patients for chlamydia, gonococci, HIV, hepatitis B and C and syphilis. Based on our small cohort, monkeypox screening in asymptomatic MSM patients in areas of low prevalence does not seem to be an appropriate approach to deal with the ongoing outbreak. Therefore, we recommend to focus more on vaccinations, targeted nonstigmatizing information and behavior recommendation for risk populations, and to engage further investigations.<\/jats:p>","DOI":"10.3390\/idr14050081","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T21:11:51Z","timestamp":1666041111000},"page":"794-797","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Screening for Monkeypox Infection in Asymptomatic High-Risk-Behaviour Men Having Sex with Men (MSM)"],"prefix":"10.3390","volume":"14","author":[{"given":"Julia","family":"Pestel","sequence":"first","affiliation":[{"name":"Infectious Disease Clinic, University Medical Center Hamburg-Eppendorf (UKE), Martinistra\u00dfe 52, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Matthews","sequence":"additional","affiliation":[{"name":"Infectious Disease Clinic, University Medical Center Hamburg-Eppendorf (UKE), Martinistra\u00dfe 52, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Schmiedel","sequence":"additional","affiliation":[{"name":"Infectious Disease Clinic, University Medical Center Hamburg-Eppendorf (UKE), Martinistra\u00dfe 52, 20246 Hamburg, Germany"},{"name":"I. Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE), 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"H\u00fcfner","sequence":"additional","affiliation":[{"name":"Infectious Disease Clinic, University Medical Center Hamburg-Eppendorf (UKE), Martinistra\u00dfe 52, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Jordan","sequence":"additional","affiliation":[{"name":"Infectious Disease Clinic, University Medical Center Hamburg-Eppendorf (UKE), Martinistra\u00dfe 52, 20246 Hamburg, Germany"},{"name":"I. Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE), 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin Luca","family":"Scheiter","sequence":"additional","affiliation":[{"name":"Infectious Disease Clinic, University Medical Center Hamburg-Eppendorf (UKE), Martinistra\u00dfe 52, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9468-7944","authenticated-orcid":false,"given":"Marc","family":"L\u00fctgehetmann","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4001-7192","authenticated-orcid":false,"given":"Dominik","family":"N\u00f6rz","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf (UKE), 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8315-6689","authenticated-orcid":false,"given":"Olaf","family":"Degen","sequence":"additional","affiliation":[{"name":"Infectious Disease Clinic, University Medical Center Hamburg-Eppendorf (UKE), Martinistra\u00dfe 52, 20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,17]]},"reference":[{"key":"ref_1","unstructured":"CDC (2022, May 19). European Centers of Disease Control Monkeypox Cases Reported in UK and Portugal. Available online: https:\/\/www.ecdc.europa.eu\/en\/news-events\/monkeypox-cases-reported-uk-and-portugal."},{"key":"ref_2","unstructured":"RKI (2022, August 28). Available online: https:\/\/www.rki.de\/DE\/Content\/InfAZ\/A\/Affenpocken\/Ausbruch-2022-Situation-Deutschland.html."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"764","DOI":"10.15585\/mmwr.mm7123e1","article-title":"Monkeypox Outbreak\u2014Nine States","volume":"71","author":"Minhaj","year":"2022","journal-title":"Morb. Mortal. Wkly. Rep. (MMWR)"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jinf.2022.05.028","article-title":"Transmission of monkeypox virus through sexual contact\u2014A novel route of infection","volume":"85","author":"Heskin","year":"2022","journal-title":"J. Infect."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.3201\/eid2809.220917","article-title":"Rapid adaptation of established high-throughput molecular testing infrastructure for detection of monkeypox virus","volume":"28","author":"Tang","year":"2022","journal-title":"Emerg. Infect. Dis."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.rr7004a1","article-title":"Sexually Transmitted Infections Treatment Guidelines, 2021","volume":"70","author":"Workowski","year":"2021","journal-title":"MMWR. Recomm. Rep."},{"key":"ref_7","unstructured":"Koch-Institut, R. (2022, September 29). Abschlussbericht: Evaluation der Einfu\u0308hrung der HIV-Pra\u0308expositionsprophylaxe als Leistung der Gesetzlichen Krankenversicherung (EvE-PrEP), Berlin 2022. 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Med., Online ahead of print.","DOI":"10.7326\/M22-2183"},{"key":"ref_11","unstructured":"(2022, August 28). RKI. Available online: https:\/\/survstat.rki.de\/Content\/Query\/Create.aspx."},{"key":"ref_12","unstructured":"CDC (2022, August 28). European Centers of Disease Control 2022 Monkeypox Outbreak Global Map, Available online: https:\/\/www.cdc.gov\/poxvirus\/monkeypox\/response\/2022\/world-map.html."},{"key":"ref_13","first-page":"3","article-title":"Beschluss der STIKO f\u00fcr die Empfehlung zur Impfung gegen Affenpocken mit Imvanex (MVA-Impfstoff)","volume":"25\/26","author":"Impfkommission","year":"2022","journal-title":"Epid. 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