{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:18:43Z","timestamp":1760149123142,"version":"build-2065373602"},"reference-count":11,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T00:00:00Z","timestamp":1688947200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infectious Disease Reports"],"abstract":"<jats:p>Intraparenchymal lung abscess development associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a rare complication, with only half a dozen primary cases having been reported in the literature. We present the case of a patient with Waldenstr\u00f6m\u2019s macroglobulinemia who developed a lung abscess subsequent to a primary SARS-CoV-2 infection. We present a 63-year-old male patient with SARS-CoV-2 infection and a history of Waldenstr\u00f6m\u2019s macroglobulinemia who developed a cavitating intraparenchymal lung abscess with an air-fluid level in his right lower lobe two weeks following admission to hospital. The patient became septic and developed acute respiratory failure requiring mechanical ventilation and intensive care. He was managed with broad-spectrum antibiotic therapy and aspiration drainage, but unfortunately due to his severe clinical condition died 20 days after his initial admission. The development of a lung abscess in patients with COVID-19, although rare, can be quite compromising and even prove fatal, especially in immunocompromised patients. Clinicians should be aware of this potential complication.<\/jats:p>","DOI":"10.3390\/idr15040039","type":"journal-article","created":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T02:05:21Z","timestamp":1689041121000},"page":"386-391","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intraparenchymal Lung Abscess Complicating a Primary COVID-19 Infection in a Patient with Waldenstr\u00f6m\u2019s Macroglobulinemia: A Case Report"],"prefix":"10.3390","volume":"15","author":[{"given":"Panagiotis F.","family":"Mavroudis","sequence":"first","affiliation":[{"name":"Second Department of Internal Medicine and Infectious Diseases Unit, Tzaneio General Hospital of Piraeus, 18536 Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lemonia","family":"Velentza","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Tzaneio General Hospital of Piraeus, 18536 Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panagiotis G.","family":"Sfyridis","sequence":"additional","affiliation":[{"name":"First Department of General Surgery, Tzaneio General Hospital of Piraeus, 18536 Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Styliani","family":"Papantoniou","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine and Diabetes Center, Tzaneio General Hospital of Piraeus, 18536 Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Kranidiotis","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine and Diabetes Center, Tzaneio General Hospital of Piraeus, 18536 Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2715-7457","authenticated-orcid":false,"given":"Efthymia","family":"Giannitsioti","sequence":"additional","affiliation":[{"name":"Fourth Department of Internal Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Stamati","sequence":"additional","affiliation":[{"name":"Third Department of Internal Medicine, Tzaneio General Hospital of Piraeus, 18536 Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7046-0112","authenticated-orcid":false,"given":"Dimitrios","family":"Schizas","sequence":"additional","affiliation":[{"name":"First Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Styliani","family":"Gerakari","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Tzaneio General Hospital of Piraeus, 18536 Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8354-4641","authenticated-orcid":false,"given":"Emmanouil I.","family":"Kapetanakis","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Tzaneio General Hospital of Piraeus, 18536 Piraeus, Greece"},{"name":"Department of Thoracic Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, 12462 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,7,10]]},"reference":[{"key":"ref_1","unstructured":"WHO (2020). Coronavirus (COVID-19), World Health Organization. Available online: https:\/\/covid19.who.int\/."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"FSO819","DOI":"10.2144\/fsoa-2022-0011","article-title":"Co-infection associated with SARS-CoV-2 and their management","volume":"8","author":"Chavda","year":"2022","journal-title":"Future Sci. OA"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.jiac.2023.02.005","article-title":"Lung abscess as a secondary infection of COVID-19: A case report and literature review","volume":"29","author":"Umamoto","year":"2023","journal-title":"J. Infect. Chemother."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1002\/ccr3.3686","article-title":"Lung abscess as a complication of COVID-19 infection, a case report","volume":"9","author":"Zamani","year":"2021","journal-title":"Clin. 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