{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T19:32:34Z","timestamp":1772825554994,"version":"3.50.1"},"reference-count":42,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infectious Disease Reports"],"abstract":"<jats:p>Background\/Objectives: Zika disease is caused by the Zika virus (ZIKV) and represents a major public health problem because of the complications in newborn babies from mothers who were infected during pregnancy. It is estimated that 80% of infected pregnant women are asymptomatic, which complicates the identification of infected individuals. In this study, we aimed to detect ZIKV in asymptomatic pregnant women and the effects in the newborns were analyzed. Methods: The presence of ZIKV was evaluated through endpoint reverse transcription\u2013polymerase chain reaction (RT-PCR) in 114 blood samples from pregnant women treated at two hospitals in the state of Veracruz, Mexico. There was a follow-up of the participants until the birth of their newborns. Results: ZIKV RNA was detected in 4.4% (n = 5) of cases. In two positive cases, two consecutive samples were obtained, and one case of persistence of ZIKV in serum after 90 days after delivery was identified. A total of 80% of the positive cases were identified after the third trimester of pregnancy and 20% after the second trimester. Although ZIKV was shown to be a risk factor for low weight and low size at birth and prematurity, after adjustment for other variables, it did not show a significant association. In contrast, preeclampsia\/eclampsia was identified as a significant risk factor for low birth weight. Conclusions: The prevalence of ZIKV found in this study suggests a latent circulation of this virus and highlights the importance of epidemiological surveillance in endemic zones. The prolonged viremia that was found suggests the need for more research because of the high impact which can mean the possible dissemination of the virus to the vector.<\/jats:p>","DOI":"10.3390\/idr17010002","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T03:38:41Z","timestamp":1736221121000},"page":"2","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Zika Virus Infection in Asymptomatic Pregnant Women"],"prefix":"10.3390","volume":"17","author":[{"given":"Kathia","family":"Guardado","sequence":"first","affiliation":[{"name":"Virus-Cell Interactions Laboratory, Institut Pasteur of Montevideo, Montevideo 11400, Uruguay"},{"name":"Biomedical Research Center, University of Veracruz, Xalapa 91190, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0996-6966","authenticated-orcid":false,"given":"Nayali","family":"L\u00f3pez-Balderas","sequence":"additional","affiliation":[{"name":"Institute of Forensic Medicine, University of Veracruz, Veracruz 94294, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1492-1797","authenticated-orcid":false,"given":"Jaime","family":"Morales-Romero","sequence":"additional","affiliation":[{"name":"Institute of Public Health, University of Veracruz, Xalapa 91190, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7495-426X","authenticated-orcid":false,"given":"Clara Luz","family":"Sampieri","sequence":"additional","affiliation":[{"name":"Institute of Public Health, University of Veracruz, Xalapa 91190, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9597-127X","authenticated-orcid":false,"given":"Roberto","family":"Zenteno-Cuevas","sequence":"additional","affiliation":[{"name":"Institute of Public Health, University of Veracruz, Xalapa 91190, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Teresa","family":"\u00c1lvarez-Ba\u00f1uelos","sequence":"additional","affiliation":[{"name":"Institute of Public Health, University of Veracruz, Xalapa 91190, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1ngel","family":"Ramos-Ligonio","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Sciences, University of Veracruz, Orizaba 94340, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4953-5076","authenticated-orcid":false,"given":"Mar\u00eda Cristina","family":"Ortiz-Le\u00f3n","sequence":"additional","affiliation":[{"name":"Institute of Public Health, University of Veracruz, Xalapa 91190, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1162-384X","authenticated-orcid":false,"given":"Miguel","family":"Varela-Cardoso","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Veracruz, Ciudad Mendoza 94740, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8090-4103","authenticated-orcid":false,"given":"Hilda","family":"Montero","sequence":"additional","affiliation":[{"name":"Virus-Cell Interactions Laboratory, Institut Pasteur of Montevideo, Montevideo 11400, Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/0035-9203(52)90042-4","article-title":"Isolations and serological specificity","volume":"46","author":"Dick","year":"1952","journal-title":"Trans. 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