{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:32:49Z","timestamp":1760243569494,"version":"build-2065373602"},"reference-count":74,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2013,9,23]],"date-time":"2013-09-23T00:00:00Z","timestamp":1379894400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>West Nile virus (WNV) appeared in the U.S. in 1999 and has since become endemic, with yearly summer epidemics causing tens of thousands of cases of serious disease over the past 14 years. Analysis of WNV strains isolated during the 2006\u20132007 epidemic seasons demonstrates that a new genetic variant had emerged coincidentally with an intense outbreak in Idaho during 2006. The isolates belonging to the new variant carry a 13 nt deletion, termed ID-\u039413, located at the variable region of the 3\u2032UTR, and are genetically related. The analysis of deletions and insertions in the 3\u2032UTR of two major lineages of WNV revealed the presence of conserved repeats and two indel motifs in the variable region of the 3\u2032UTR. One human and two bird isolates from the Idaho 2006\u20132007 outbreaks were sequenced using Illumina technology and within-host variability was analyzed. Continued monitoring of new genetic variants is important for public health as WNV continues to evolve.<\/jats:p>","DOI":"10.3390\/ijerph10094486","type":"journal-article","created":{"date-parts":[[2013,9,24]],"date-time":"2013-09-24T04:54:41Z","timestamp":1379998481000},"page":"4486-4506","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Genetic Analysis of West Nile Virus Isolates from an Outbreak in Idaho, United States, 2006\u20132007"],"prefix":"10.3390","volume":"10","author":[{"given":"Andriyan","family":"Grinev","sequence":"first","affiliation":[{"name":"Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda,  MD 20892, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caren","family":"Chancey","sequence":"additional","affiliation":[{"name":"Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda,  MD 20892, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Germ\u00e1n","family":"A\u00f1ez","sequence":"additional","affiliation":[{"name":"Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda,  MD 20892, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Ball","sequence":"additional","affiliation":[{"name":"Idaho Bureau of Laboratories, Boise, ID 83712, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie","family":"Winkelman","sequence":"additional","affiliation":[{"name":"Creative Testing Solutions, Tempe, AZ 85282, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillip","family":"Williamson","sequence":"additional","affiliation":[{"name":"Creative Testing Solutions, Tempe, AZ 85282, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Foster","sequence":"additional","affiliation":[{"name":"American Red Cross, Gaithersburg, MD 20877, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Stramer","sequence":"additional","affiliation":[{"name":"American Red Cross, Gaithersburg, MD 20877, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Rios","sequence":"additional","affiliation":[{"name":"Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda,  MD 20892, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2013,9,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1111\/j.1751-2824.2012.01602.x","article-title":"Dengue virus and other arboviruses: A global view of risks","volume":"7","author":"Chancey","year":"2012","journal-title":"ISBT Sci. 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