{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:52:09Z","timestamp":1790729529933,"version":"4.1.0"},"reference-count":38,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T00:00:00Z","timestamp":1387152000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>This special issue of International Journal of Environmental Research and Public Health is dedicated to leptospirosis, an endemic zoonotic disease that is a cause of many acute undifferentiated fevers, especially in tropical countries [1,2]. While it can be debated whether leptospirosis is an emerging disease, it is evident that it is becoming an emerging public health problem. 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Human Leptospirosis: Guidance for Diagnosis, Surveillance and Control, WHO."},{"key":"ref_5","unstructured":"World Health Organization (2010). Report of the First Meeting of the Leptospirosis Burden Epidemiology Reference Group, WHO."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1086\/314424","article-title":"Epidemic leptospirosis associated with pulmonary hemorrhage\u2014Nicar\u00e1gua, 1995","volume":"178","author":"Trevejo","year":"1998","journal-title":"J. Inf. Dis."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.3201\/eid1006.030660","article-title":"Environmental exposure and leptospirosis, Peru","volume":"10","author":"Johnson","year":"2004","journal-title":"Emerg. Infect. 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Dis."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3201\/eid1801.101892","article-title":"Outbreak of leptospirosis after flood, the Philippines, 2009","volume":"18","author":"Amilasan","year":"2012","journal-title":"Emerg. Infect. Dis."},{"key":"ref_13","unstructured":"HealthMap. Available online:http:\/\/healthmap.org\/en\/."},{"key":"ref_14","first-page":"193","article-title":"Natural disasters and communicable diseases in the Americas: Contribution of Veterinary Public Health","volume":"48","author":"Schneider","year":"2012","journal-title":"Vet. Ital."},{"key":"ref_15","unstructured":"Pan American Health Organization (2012). Health in the Americas\u2014Regional Outlook and Country Profiles, Pan American Health Organization. 2012 Edition."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1590\/S1020-49892012000900001","article-title":"Surveillance for leptospirosis in the Americas, 1996\u20132005: A review of data from ministries of health","volume":"32","author":"Costa","year":"2012","journal-title":"Rev. Panam. Salud P\u00fablica"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/S0140-6736(99)80012-9","article-title":"Urban epidemic of severe leptospirosis in Brazil","volume":"354","author":"Ko","year":"1999","journal-title":"Lancet"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"3883","DOI":"10.3390\/ijerph9113883","article-title":"Leptospirosis outbreaks in Nicaragua: Identifying critical areas and exploring drivers for evidence-based planning","volume":"9","author":"Schneider","year":"2012","journal-title":"Int. J. Environ. Res. Public Health."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"e154","DOI":"10.1371\/journal.pntd.0000154","article-title":"Household transmission of leptospira infection in urban slum communities","volume":"2","author":"Maciel","year":"2008","journal-title":"PLoS Negl. Trop. Dis."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"e1669","DOI":"10.1371\/journal.pntd.0001669","article-title":"Leptospirosis in American Samoa\u2014Estimating and mapping risk using environmental data","volume":"6","author":"Lau","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"key":"ref_21","first-page":"39","article-title":"Sero-prevalence of leptospirosis in workers at a New Zealand slaughterhouse","volume":"122","author":"Benschop","year":"2009","journal-title":"N. Z. Med. J."},{"key":"ref_22","first-page":"169","article-title":"Determinaci\u00f3n serol\u00f3gica de Leptospirosis y brucelosis en individuos expuestos al riesgo","volume":"12","author":"Lopez","year":"1996","journal-title":"Agro-Ciencia Chile"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"610","DOI":"10.4269\/ajtmh.1999.60.610","article-title":"Leptospirosis and Ebola virus infection in five gold-panning villages in northeastern Gabon","volume":"60","author":"Bertherat","year":"1999","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"702","DOI":"10.3201\/eid0906.020751","article-title":"Leptospirosis in \u2018\u2018Eco-Challenge\u2019\u2019 athletes, Malaysian Borneo","volume":"9","author":"Sejvar","year":"2003","journal-title":"Emerg. Infect. Dis."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1590\/S0034-89102011005000070","article-title":"Years of potential life lost and hospitalization costs associated with leptospirosis in Brazil","volume":"45","author":"Souza","year":"2011","journal-title":"Revista de Sa\u00fade P\u00fablica"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4103\/0974-2700.40573","article-title":"Leptospirosis: The \u201cmysterious\u201d mimic","volume":"1","author":"Izurieta","year":"2008","journal-title":"J. Emerg. Trauma Shock"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1590\/S0037-86822007000400012","article-title":"Anticorpos anti-Leptospira em pacientes do Mato Grosso do Sul com suspeita cl\u00ednica de dengue e hepatite viral","volume":"40","author":"Souza","year":"2007","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0255-0857(21)02306-9","article-title":"Leptospirosis: Current status and future trends","volume":"24","author":"Hartskeerl","year":"2006","journal-title":"Indian J. Med. Microbiol."},{"key":"ref_29","unstructured":"World Health Organization (2008). International Health Regulations, 2005, WHO."},{"key":"ref_30","unstructured":"Acha, P.N., and Szyfres, B. (2003). Zoonoses and Communicable Diseases Common to Man and Animals, Pan American Health Organization. [3rd ed.]."},{"key":"ref_31","unstructured":"Pan American Health Organization Available online:http:\/\/www.paho.org\/hq\/index.php?option=com_content&view=article&id=7868&Itemid=39698&lang=en."},{"key":"ref_32","first-page":"311","article-title":"Infectious diseases and natural disasters: The effects of Hurricane Mitch over Villanueva municipal area, Nicaragua","volume":"27","author":"Campanella","year":"1999","journal-title":"Public Health Rev."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1590\/S0102-311X2001000700014","article-title":"The place behind the case: Leptospirosis risks and associated environmental conditions in a flood-related outbreak in Rio de Janeiro","volume":"Suppl. 17","author":"Barcellos","year":"2001","journal-title":"Cad. 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Parasitol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1590\/S0102-311X2003000500007","article-title":"Spatial distribution of leptospirosis in Rio Grande do Sul, Brazil: Recovering the ecology of ecological studies","volume":"19","author":"Barcellos","year":"2003","journal-title":"Cadernos de Sa\u00fade P\u00fablica"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Reis, R.B., Ribeiro, G.S., Felzemburgh, R.D.M., Santana, F.S., Mohr, S., Melendez, A.X., Queiroz, A., Santos, A.C., Ravines, R.R., and Tassinari, W.S. (2008). Impact of environmental and social gradient onLeptospira infection in urban slums. PLoS Negl. Trop. Dis., 2.","DOI":"10.1371\/journal.pntd.0000228"},{"key":"ref_38","unstructured":"Global Leptospirosis Environmental Action Network. 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