{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T11:42:04Z","timestamp":1782819724917,"version":"3.54.5"},"reference-count":67,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2013,12,24]],"date-time":"2013-12-24T00:00:00Z","timestamp":1387843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Only a few studies have examined the efficacy and safety of smoking cessation programmes in patients with mental disorders. The aim of this paper is to describe in detail the methodology used in the study as well as the Multi-component Smoking Cessation Support Programme in terms of pharmacological treatments and psychological interventions. An open-label 9-month follow-up study was conducted in Spain. A total of 82 clinically stable outpatients with schizophrenia, schizoaffective or bipolar disorder were enrolled. Treatment consisted of a programme specifically developed by the research team for individuals with severe mental disorders. The programme consisted of two phases:  (1) weekly individual motivational therapy for 4\u201312 weeks, and (2) a 12-week active treatment phase. During this phase, at each study visit patients received a one- or two-week supply of medication (transdermal nicotine patches, varenicline or bupropion) with instructions on how to take it, in addition to group psychotherapy for smoking cessation. Evaluations were performed: (1) at the time of enrolment in the study, (2) during the  12-week active treatment phase of the study (weekly for the first 4 weeks and then biweekly), and (3) after the end of this phase (two follow-up assessments at weeks 12 and 24). Evaluations included: (1) smoking history, (2) substance use, (3) psychopathology,  (4) adverse events, and (5) laboratory tests. The importance of this study lies in addressing a topical issue often ignored by psychiatrists: the unacceptably high rates of tobacco use in patients with severe mental disorders.<\/jats:p>","DOI":"10.3390\/ijerph110100373","type":"journal-article","created":{"date-parts":[[2013,12,24]],"date-time":"2013-12-24T09:06:57Z","timestamp":1387876017000},"page":"373-389","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Effectiveness of a Multi-Component Smoking Cessation Support Programme (McSCSP) for Patients with Severe Mental Disorders: Study Design"],"prefix":"10.3390","volume":"11","author":[{"given":"Maria","family":"Garcia-Portilla","sequence":"first","affiliation":[{"name":"Departmento de Psiquiatr\u00eda, Universidad de Oviedo, 33006 Oviedo, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental, CIBERSAM, Universidad de Oviedo, 33006 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leticia","family":"Garcia-Alvarez","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental, CIBERSAM, Universidad de Oviedo, 33006 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Saiz","sequence":"additional","affiliation":[{"name":"Departmento de Psiquiatr\u00eda, Universidad de Oviedo, 33006 Oviedo, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental, CIBERSAM, Universidad de Oviedo, 33006 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Diaz-Mesa","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental, CIBERSAM, Universidad de Oviedo, 33006 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Galvan","sequence":"additional","affiliation":[{"name":"Universidad Nacional de la Patagonia Austral, Puerto San Juli\u00e1n, 9310 Santa Cruz, Argentina"},{"name":"Instituto Interuniversitario de Postgrado en Salud, Santa Rosa, 6300 La Pampa, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Sarramea","sequence":"additional","affiliation":[{"name":"Complejo Hospitalario de Ja\u00e9n, Equipo de Salud Mental de And\u00fajar, 23740 Ja\u00e9n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josefa","family":"Garcia-Blanco","sequence":"additional","affiliation":[{"name":"Complejo Hospitalario de Ja\u00e9n, Equipo de Salud Mental de And\u00fajar, 23740 Ja\u00e9n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edorta","family":"Elizagarate","sequence":"additional","affiliation":[{"name":"Unidad de Psicosis Refractarias, Hospital Psiqui\u00e1trico de \u00c1lava, 01006 Vitoria, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental, CIBERSAM, Universidad del Pa\u00eds Vasco, 48940 Leioa-Bizkaia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"Bobes","sequence":"additional","affiliation":[{"name":"Departmento de Psiquiatr\u00eda, Universidad de Oviedo, 33006 Oviedo, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental, CIBERSAM, Universidad de Oviedo, 33006 Oviedo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2013,12,24]]},"reference":[{"key":"ref_1","unstructured":"Shafey, O., Eriksen, M., Ross, H., and Mackay, J. 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