{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T23:12:42Z","timestamp":1791673962968,"version":"4.3.4"},"reference-count":29,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2014,9,10]],"date-time":"2014-09-10T00:00:00Z","timestamp":1410307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Our aim is to describe the study recruitment and baseline characteristics of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) study population. Potential study participants (age 60\u201377 years, the dementia risk score \u22656) were identified from previous population-based survey cohorts and invited to the screening visit. To be eligible, cognitive performance measured at the screening visit had to be at the mean level or slightly lower than expected for age. Of those invited  (n = 5496), 48% (n = 2654) attended the screening visit, and finally 1260 eligible participants were randomized to the intervention and control groups (1:1). The screening visit non-attendees were slightly older, less educated, and had more vascular risk factors and diseases present. The mean (SD) age of the randomized participants was 69.4 (4.7) years, Mini-Mental State Examination 26.7 (2.0) points, systolic blood pressure  140.1 (16.2) mmHg, total serum cholesterol 5.2 (1.0) mmol\/L for, and fasting glucose  6.1 (0.9) mmol\/L for, with no difference between intervention and control groups. Several modifiable risk factors were present at baseline indicating an opportunity for the intervention. The FINGER study will provide important information on the effect of lifestyle intervention to prevent cognitive impairment among at risk persons.<\/jats:p>","DOI":"10.3390\/ijerph110909345","type":"journal-article","created":{"date-parts":[[2014,9,11]],"date-time":"2014-09-11T02:22:24Z","timestamp":1410402144000},"page":"9345-9360","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":90,"title":["Recruitment and Baseline Characteristics of Participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)\u2014A Randomized Controlled Lifestyle Trial"],"prefix":"10.3390","volume":"11","author":[{"given":"Tiia","family":"Ngandu","sequence":"first","affiliation":[{"name":"Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland"},{"name":"Alzheimer's Disease Research Center, Karolinska Institutet, Novum 5th floor,  SE-14157 Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenni","family":"Lehtisalo","sequence":"additional","affiliation":[{"name":"Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esko","family":"Lev\u00e4lahti","sequence":"additional","affiliation":[{"name":"Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiina","family":"Laatikainen","sequence":"additional","affiliation":[{"name":"Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland"},{"name":"Institute of Public Health and Clinical Nutrition, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaana","family":"Lindstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markku","family":"Peltonen","sequence":"additional","affiliation":[{"name":"Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina","family":"Solomon","sequence":"additional","affiliation":[{"name":"Alzheimer's Disease Research Center, Karolinska Institutet, Novum 5th floor,  SE-14157 Stockholm, Sweden"},{"name":"Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland,  P.O. Box 1627, FI-70211 Kuopio, Finland"},{"name":"Aging Research Center, Karolinska Institutet\u2014Stockholm University, G\u00e4vlegatan 16,  SE-11330 Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satu","family":"Ahtiluoto","sequence":"additional","affiliation":[{"name":"Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riitta","family":"Antikainen","sequence":"additional","affiliation":[{"name":"Institute of Health Sciences\/Geriatrics, University of Oulu, and Oulu University Hospital,  P.O. Box 5000, FI-90014 University of Oulu, Finland"},{"name":"Medical Research Center Oulu, Oulu University Hospital and University of Oulu, P.O. Box 5000, FI-90014 University of Oulu, Finland"},{"name":"Oulu City Hospital, Kiviharjuntie 5, FI-90015 Oulu, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuomo","family":"H\u00e4nninen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kuopio University Hospital, P.O. Box 100, FI-70029 KYS, Kuopio, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antti","family":"Jula","sequence":"additional","affiliation":[{"name":"Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Mangialasche","sequence":"additional","affiliation":[{"name":"Aging Research Center, Karolinska Institutet\u2014Stockholm University, G\u00e4vlegatan 16,  SE-11330 Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teemu","family":"Paajanen","sequence":"additional","affiliation":[{"name":"Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, FI-00250 Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satu","family":"Pajala","sequence":"additional","affiliation":[{"name":"Department of Lifestyle and Participation, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer","family":"Rauramaa","sequence":"additional","affiliation":[{"name":"Kuopio Research Institute of Exercise Medicine, Kuopion yliopisto, Haapaniementie 16,  70100 Kuopio, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"Strandberg","sequence":"additional","affiliation":[{"name":"Institute of Health Sciences\/Geriatrics, University of Oulu, and Oulu University Hospital,  P.O. Box 5000, FI-90014 University of Oulu, Finland"},{"name":"Department of Medicine, Geriatric Clinic, University of Helsinki, and Helsinki University Central Hospital, P.O. Box 22, FI-00014 University of Helsinki, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaakko","family":"Tuomilehto","sequence":"additional","affiliation":[{"name":"Department of Public Health, University of Helsinki, P.O. Box 40, FI-00014 University of Helsinki, Finland"},{"name":"South Ostrobothnia Central Hospital, Huhtalantie 53, FI-60220 Sein\u00e4joki, Finland"},{"name":"Center for Vascular Prevention, Danube-University Krems, Dr.-Karl-Dorrek-Str. 30,  3500 Krems, Austria"},{"name":"Diabetes Research Group, King Abdulaziz University, P.O. Box 80200, Jeddah 21589,  Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilkka","family":"Soininen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland,  P.O. Box 1627, FI-70211 Kuopio, Finland"},{"name":"Department of Neurology, Kuopio University Hospital, P.O. Box 100, FI-70029 KYS, Kuopio, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miia","family":"Kivipelto","sequence":"additional","affiliation":[{"name":"Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland"},{"name":"Alzheimer's Disease Research Center, Karolinska Institutet, Novum 5th floor,  SE-14157 Stockholm, Sweden"},{"name":"Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland,  P.O. Box 1627, FI-70211 Kuopio, Finland"},{"name":"Aging Research Center, Karolinska Institutet\u2014Stockholm University, G\u00e4vlegatan 16,  SE-11330 Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2014,9,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jalz.2012.11.007","article-title":"The global prevalence of dementia: A systematic review and metaanalysis","volume":"9","author":"Prince","year":"2013","journal-title":"Alzheimers Dement."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Mangialasche, F., Kivipelto, M., Solomon, A., and Fratiglioni, L. (2012). 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