{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:42:53Z","timestamp":1791272573804,"version":"4.1.0"},"reference-count":165,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2015,6,18]],"date-time":"2015-06-18T00:00:00Z","timestamp":1434585600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NHS R&amp;D National Primary Care Researcher Development Award Fellowship","award":["RDA99\/062"],"award-info":[{"award-number":["RDA99\/062"]}]},{"name":"NHS R&amp;D Eastern Region Health Services and Public Health Research Scheme Grant","award":["HSR\/0500\/1"],"award-info":[{"award-number":["HSR\/0500\/1"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>This article presents an evidence-based reasoning, focusing on evidence of an Occupational Therapy input to lifestyle behaviour influences on panic disorder that also provides potentially broader application across other mental health problems (MHP).  The article begins from the premise that we are all different. It then follows through a sequence of questions, examining incrementally how MHPs are experienced and classified. It analyses the impact of individual sensitivity at different levels of analysis, from genetic and epigenetic individuality, through neurotransmitter and body system sensitivity. Examples are given demonstrating the evidence base behind the logical sequence of investigation. The paper considers the evidence of how everyday routine lifestyle behaviour impacts on occupational function at all levels, and how these behaviours link to individual sensitivity to influence the level of exposure required to elicit symptomatic responses. Occupational Therapists can help patients by adequately assessing individual sensitivity, and through promoting understanding and a sense of control over their own symptoms. It concludes that present clinical guidelines should be expanded to incorporate knowledge of individual sensitivities to environmental exposures and lifestyle behaviours at an early stage.<\/jats:p>","DOI":"10.3390\/ijerph120607017","type":"journal-article","created":{"date-parts":[[2015,6,18]],"date-time":"2015-06-18T10:08:54Z","timestamp":1434622134000},"page":"7017-7043","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Lifestyle Behaviours Add to the Armoury of Treatment Options for Panic Disorder: An Evidence-Based Reasoning"],"prefix":"10.3390","volume":"12","author":[{"given":"Rod","family":"Lambert","sequence":"first","affiliation":[{"name":"School of Health Sciences and Health Economics Consulting, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich NR4 7TJ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2015,6,18]]},"reference":[{"key":"ref_1","unstructured":"World Economic Forum and McKinsey & Company (2013). 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