{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:18:21Z","timestamp":1760242701787,"version":"build-2065373602"},"reference-count":23,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T00:00:00Z","timestamp":1455840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["R01ES014717","R01ES020415","P30ES005022"],"award-info":[{"award-number":["R01ES014717","R01ES020415","P30ES005022"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>While the association of eczema with asthma is well recognized, little research has focused on the potential role of inhalable exposures and eczema. While indoor air quality is important in the development of respiratory disease as children in the U.S. spend the majority of their time indoors, relatively little research has focused on correlated non-respiratory conditions. This study examined the relationship between particulate matter (PM) exposures in preschool age children and major correlates of asthma, such as wheeze and eczema. Air sampling was carried out using a robotic (PIPER) child-sampling surrogate. This study enrolled 128 participants, 57 male and 71 female children. Ages ranged from 3 to 58 months with the mean age of 29.3 months. A comparison of subjects with and without eczema showed a difference in the natural log (ln) of PM collected from the PIPER air sampling (p = 0.049). PIPER\u2019s sampling observed an association between the ln PM concentrations and eczema, but not an association with wheezing history in pre-school children. Our findings are consistent with the hypothesis of the role of the microenvironment in mediating atopic dermatitis, which is one of the predictors of persistent asthma. Our findings also support the use of PIPER in its ability to model and sample the microenvironment of young children.<\/jats:p>","DOI":"10.3390\/ijerph13020242","type":"journal-article","created":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T11:29:39Z","timestamp":1455881379000},"page":"242","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Use of a Robotic Sampler (PIPER) for Evaluation of Particulate Matter Exposure and Eczema in Preschoolers"],"prefix":"10.3390","volume":"13","author":[{"given":"Lokesh","family":"Shah","sequence":"first","affiliation":[{"name":"Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gediminas","family":"Mainelis","sequence":"additional","affiliation":[{"name":"Department of Environmental Sciences, Rutgers The State University of New Jersey, New Brunswick, NJ 08901, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maya","family":"Ramagopal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen","family":"Black","sequence":"additional","affiliation":[{"name":"Environmental and Occupational Health Sciences Institute, Piscataway, NJ 08854, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart","family":"Shalat","sequence":"additional","affiliation":[{"name":"Division of Environmental Health, School of Public Health, Georgia State University, Atlanta, GA 30303, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2016,2,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/sj.jea.7500165","article-title":"The National Human Activity Pattern Survey (NHAPS): A resource for assessing exposure to environmental pollutants","volume":"11","author":"Klepeis","year":"2001","journal-title":"J. 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