{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T08:13:40Z","timestamp":1763367220207,"version":"build-2065373602"},"reference-count":20,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2016,11,7]],"date-time":"2016-11-07T00:00:00Z","timestamp":1478476800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Background: Approximately 35 new HIV (Human Immunodeficiency Virus, HIV) cases and at least 1000 serious infections are transmitted annually to health care workers. In China, HIV prevalence is increasing and nursing personnel are encountering these individuals more than in the past. Contaminated needle-stick injuries represent a significant occupational burden for nurses. Evidence suggests that nurses in China may not fully understand HIV\/AIDS (Acquired immunodeficiency syndrome, AIDS) and HIV-related occupational safety. At this time, universal protection precautions are not strictly implemented in Chinese hospitals. Lack of training may place nurses at risk for occupational exposure to blood-borne pathogens. Objectives: To assess the effectiveness of integrated interventions on nurses\u2019 knowledge improvement about reducing the risk of occupationally acquired HIV infection. Methods: We audited integrated interventions using 300 questionnaires collected from nurses at the Affiliated Hospital of Xiangnan University, a public polyclinic in Hunan Province. The intervention studied was multifaceted and included appropriate and targeted training content for hospital, department and individual levels. After three months of occupational safety integrated interventions, 234 participants who completed the program were assessed. Results: Of the subjects studied, 94.3% (283\/300) were injured one or more times by medical sharp instruments or splashed by body fluids in the last year and 95.3% considered their risk of occupational exposure high or very high. After the intervention, awareness of HIV\/AIDS-related knowledge improved significantly (\u03c72 = 86.34, p = 0.00), and correct answers increased from 67.9% to 82.34%. Correct answers regarding risk perception were significantly different between pre-test (54.4%) and post-test (66.6%) (\u03c72 = 73.2, p = 0.00). When coming into contact with patient body fluids and blood only 24.0% of subjects used gloves regularly. The pre-test knowledge scores on universal precautions were relatively high. Correct answers about universal precautions improved significantly from pre-test (83.71%) to post-test (89.58%; \u03c72 = 25.00, p = 0.00). After the intervention, nurses\u2019 attitude scores improved significantly from pre-test (3.80 \u00b1 0.79) to post-test (4.06 \u00b1 0.75; t = 3.74, p = 0.00). Conclusions: Integrated educational interventions enhance nurses\u2019 knowledge of risk reduction for occupationally acquired HIV infections and improve the observance of universal precautionary procedures. This enhancement allows nurses to assume a teaching role for prevention and management of HIV\/AIDS.<\/jats:p>","DOI":"10.3390\/ijerph13111094","type":"journal-article","created":{"date-parts":[[2016,11,7]],"date-time":"2016-11-07T10:36:50Z","timestamp":1478515010000},"page":"1094","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["An Integrated Intervention for Increasing Clinical Nurses\u2019 Knowledge of HIV\/AIDS-Related Occupational Safety"],"prefix":"10.3390","volume":"13","author":[{"given":"Liping","family":"He","sequence":"first","affiliation":[{"name":"School of Public Health, Wuhan University, Wuhan 430072, China"},{"name":"School of Public Health, Xiangnan University, Chenzhou 423000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiyan","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zhongnan Hospital of Wuhan University, Wuchang District, Wuhan 430072, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Huang","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Xiangnan University, Chenzhou 423000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiping","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Public Health, Xiangnan University, Chenzhou 423000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Huang","sequence":"additional","affiliation":[{"name":"Chenzhou City Center for Disease Control and Prevention, Chenzhou 423000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongyi","family":"Bi","sequence":"additional","affiliation":[{"name":"School of Public Health, Wuhan University, Wuhan 430072, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[{"name":"School of Public Health, Xiangnan University, Chenzhou 423000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2016,11,7]]},"reference":[{"key":"ref_1","unstructured":"Joint United Nations Programme on HIV\/AIDS (UNAIDS), and World Health Organization (WHO) (2015). 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