{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T09:05:30Z","timestamp":1792487130764,"version":"4.5.0"},"reference-count":39,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2017,4,14]],"date-time":"2017-04-14T00:00:00Z","timestamp":1492128000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["NSFC 81370106"],"award-info":[{"award-number":["NSFC 81370106"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["NSFC 30801210"],"award-info":[{"award-number":["NSFC 30801210"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Air pollutants are associated with cardiovascular death; however, there is limited evidence of the effects of different pollutants on out-of-hospital cardiac arrests (OHCAs) in Beijing, China. We aimed to investigate the associations of OHCAs with the air pollutants PM2.5\u201310 (coarse particulate matter), PM2.5 (particles \u22642.5 \u03bcm in aerodynamic diameter), nitrogen dioxide (NO2), sulfur dioxide (SO2), carbon monoxide (CO), and ozone (O3) between 2013 and 2015 using a time-stratified case-crossover study design. We obtained health data from the nationwide emergency medical service database; 4720 OHCA cases of cardiac origin were identified. After adjusting for relative humidity and temperature, the highest odds ratios of OHCA for a 10 \u03bcg\/m3 increase in PM2.5 were observed at Lag Day 1 (1.07; 95% confidence interval (CI): 1.04\u20131.10), with strong associations with advanced age (aged \u226570 years) (1.09; 95% CI: 1.05\u20131.13) and stroke history (1.11; 95% CI: 1.06\u20131.16). PM2.5\u201310 and NO2 also showed significant associations with OHCAs, whereas SO2, CO, and O3 had no effects. After simultaneously adjusting for NO2 and SO2 in a multi-pollutant model, PM2.5 remained significant. The effects of PM2.5 in the single-pollutant models for cases with hypertension, respiratory disorders, diabetes mellitus, and heart disease were higher than those for cases without these complications; however, the differences were not statistically significant. The results support that elevated PM2.5 exposure contributes to triggering OHCA, especially in those who are advanced in age and have a history of stroke.<\/jats:p>","DOI":"10.3390\/ijerph14040423","type":"journal-article","created":{"date-parts":[[2017,4,18]],"date-time":"2017-04-18T11:22:04Z","timestamp":1492514524000},"page":"423","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Ambient Air Pollution and Out-of-Hospital Cardiac Arrest in Beijing, China"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0968-9372","authenticated-orcid":false,"given":"Ruixue","family":"Xia","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, First Hospital, Health Sciences Centre, Peking University, 8 Xishiku Rd., Beijing 100034, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3507-8070","authenticated-orcid":false,"given":"Guopeng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Hospital Information, First Hospital, Health Sciences Centre, Peking University, 8 Xishiku Rd., Beijing 100034, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Zhu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering and Centre for Environment and Health, Peking University, Beijing 100871, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueying","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Hospital Information, First Hospital, Health Sciences Centre, Peking University, 8 Xishiku Rd., Beijing 100034, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangfa","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, First Hospital, Health Sciences Centre, Peking University, 8 Xishiku Rd., Beijing 100034, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2017,4,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Writing Group Members, Mozaffarian, D., Benjamin, E.J., Go, A.S., Arnett, D.K., Blaha, M.J., Cushman, M., Das, S.R., de Ferranti, S., and Despres, J.P. 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