{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T01:26:20Z","timestamp":1792891580948,"version":"4.5.0"},"reference-count":40,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2018,10,10]],"date-time":"2018-10-10T00:00:00Z","timestamp":1539129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Korean Centers for Disease Control and Prevention","award":["2013E2100101"],"award-info":[{"award-number":["2013E2100101"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Research has shown the effects of climatic factors on shigellosis; however, no previous study has evaluated climatic effects in regions with a winter seasonality of shigellosis incidence. We examined the effects of temperature and precipitation on shigellosis incidence in Korea from 2002\u20132010. The incidence of shigellosis was calculated based on data from the Korean Center for Disease Control and Prevention (KCDC, Cheongju, Korea), and a generalized additive model (GAM) was used to analyze the associations between the incidence and climatic factors. The annual incidence rate of shigellosis was 7.9 cases\/million persons from 2002\u20132010. During 2007\u20132010, high incidence rates and winter seasonality were observed among those aged \u226565 years, but not among lower age groups. Based on the GAM model, the incidence of shigellosis is expected to increase by 13.6% and 2.9% with a temperature increase of 1 \u00b0C and a lag of two weeks and with a mean precipitation increase of 1 mm and a lag of five weeks after adjustment for seasonality, respectively. This study suggests that the incidence of shigellosis will increase with global climate change despite the winter seasonality of shigellosis in Korea. Public health action is needed to prevent the increase of shigellosis incidence associated with climate variations.<\/jats:p>","DOI":"10.3390\/ijerph15102209","type":"journal-article","created":{"date-parts":[[2018,10,10]],"date-time":"2018-10-10T11:53:13Z","timestamp":1539172393000},"page":"2209","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["The Epidemiological Influence of Climatic Factors on Shigellosis Incidence Rates in Korea"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5543-8574","authenticated-orcid":false,"given":"Yeong-Jun","family":"Song","sequence":"first","affiliation":[{"name":"Department of Preventive Medicine College of Medicine, Eulji University, Daejeon 34824, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2758-9399","authenticated-orcid":false,"given":"Hae-Kwan","family":"Cheong","sequence":"additional","affiliation":[{"name":"Department of Social and Preventive Medicine, Sungkyunkwan University School of Medicine, Suwon 16419, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung","family":"Ki","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, College of Medicine, Korea University, Seoul 02841, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Yeon","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-sik","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Public Health Science, Graduate School of Public Health, Seoul National University, Seoul 08826, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mira","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine College of Medicine, Eulji University, Daejeon 34824, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moran","family":"Ki","sequence":"additional","affiliation":[{"name":"Department of Cancer Control and Population Health, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang 10408, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8761-3744","authenticated-orcid":false,"given":"Jiseun","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine College of Medicine, Eulji University, Daejeon 34824, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,10,10]]},"reference":[{"key":"ref_1","first-page":"651","article-title":"Global burden of Shigella infections: Implications for vaccine development and implementation of control strategies","volume":"77","author":"Kotloff","year":"1999","journal-title":"Bull. World Health Organ."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"S102","DOI":"10.1093\/clinids\/24.Supplement_1.S102","article-title":"Antimicrobial resistance in organisms causing diarrheal disease","volume":"24","author":"Sack","year":"1997","journal-title":"Clin. Infect. Dis."},{"key":"ref_3","unstructured":"Heymann, D.L. (2008). Control of Communicable Diseases Manual, American Public Health Association."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4167\/jbv.2006.36.2.41","article-title":"Epidemiology of shigellosis in Korea","volume":"36","author":"Lee","year":"2006","journal-title":"J. Bacteriol. Virol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1034\/j.1600-0463.2001.090307.x","article-title":"Antimicrobial resistance of Shigella sonnei in Korea during the last two decades","volume":"109","author":"Lee","year":"2001","journal-title":"Apmis"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1099\/jmm.0.46441-0","article-title":"Molecular characterization of antimicrobial resistance in Shigella sonnei isolates in Korea","volume":"55","author":"Seol","year":"2006","journal-title":"J. Med. Microbiol."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Chen, M.-J., Lin, C.-Y., Wu, Y.-T., Wu, P.-C., Lung, S.-C., and Su, H.-J. (2012). Effects of extreme precipitation to the distribution of infectious diseases in Taiwan, 1994\u20132008. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0034651"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"697","DOI":"10.4269\/ajtmh.13-0198","article-title":"Meteorological variables and bacillary dysentery cases in Changsha City, China","volume":"90","author":"Gao","year":"2014","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"356","DOI":"10.7883\/yoken.JJID.2008.356","article-title":"Bacillary dysentery and meteorological factors in northeastern China: A historical review based on classification and regression trees","volume":"61","author":"Guan","year":"2008","journal-title":"Jpn. J. Infect. Dis."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Huang, D., Guan, P., Guo, J., Wang, P., and Zhou, B. (2008). Investigating the effects of climate variations on bacillary dysentery incidence in northeast China using ridge regression and hierarchical cluster analysis. BMC Infect. Dis., 8.","DOI":"10.1186\/1471-2334-8-130"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1289\/ehp.9658","article-title":"Temporal trends and climatic factors associated with bacterial enteric diseases in Vietnam, 1991\u20132001","volume":"116","author":"Alonso","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s40249-017-0325-z","article-title":"Seasonal and geographical distribution of bacillary dysentery (shigellosis) and associated climate risk factors in Kon Tum Province in Vietnam from 1999 to 2013","volume":"6","author":"Lee","year":"2017","journal-title":"Infect. Dis. Poverty"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"3239","DOI":"10.1038\/srep03239","article-title":"Identifying high-risk areas of bacillary dysentery and associated meteorological factors in Wuhan, China","volume":"3","author":"Li","year":"2013","journal-title":"Sci. Rep."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Ma, W., Sun, X., Song, Y., Tao, F., Feng, W., He, Y., Zhao, N., and Yuan, Z. (2013). Applied mixed generalized additive model to assess the effect of temperature on the incidence of bacillary dysentery and its forecast. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0062122"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1177\/003335490812300109","article-title":"Weather and the transmission of bacillary dysentery in Jinan, northern China: A time-series analysis","volume":"123","author":"Zhang","year":"2008","journal-title":"Public Health Rep."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jinf.2006.12.002","article-title":"Climate variations and bacillary dysentery in northern and southern cities of China","volume":"55","author":"Zhang","year":"2007","journal-title":"J. Infect."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"527","DOI":"10.5124\/jkma.2003.46.6.527","article-title":"Bacillary dysentery","volume":"46","author":"Pai","year":"2003","journal-title":"J. Korean Med. Assoc."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.phrp.2015.07.005","article-title":"Enteric bacteria isolated from diarrheal patients in Korea in 2014","volume":"6","author":"Kim","year":"2015","journal-title":"Osong Public Health Res. Perspect."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"e2014030","DOI":"10.4178\/epih\/e2014030","article-title":"National Infectious Diseases Surveillance data of South Korea","volume":"36","author":"Park","year":"2014","journal-title":"Epidemiol. Health"},{"key":"ref_20","first-page":"13","article-title":"Production and validation of daily grid data with 1 km resolution in South Korea","volume":"8","author":"Kim","year":"2013","journal-title":"J. Clim. Res."},{"key":"ref_21","first-page":"55","article-title":"Production technique of observation grid data of 1 km resolution","volume":"7","author":"Kim","year":"2012","journal-title":"J. Clim. Res."},{"key":"ref_22","unstructured":"Bogin, B., and Smith, B.H. (2000). Evolution of the Human Life Cycle, Wiley-Liss."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1467-985X.2011.00714.x","article-title":"Statistical methods for the prospective detection of infectious disease outbreaks: A review","volume":"175","author":"Unkel","year":"2012","journal-title":"J. R. Stat. Soc. Ser. A Stat. Soc."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Jajosky, R.A., and Groseclose, S.L. (2004). Evaluation of reporting timeliness of public health surveillance systems for infectious diseases. BMC Public Health, 4.","DOI":"10.1186\/1471-2458-4-29"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1017\/S0950268803008355","article-title":"A case\u2013control study of risk factors for sporadic Campylobacter infections in Denmark","volume":"130","author":"Neimann","year":"2003","journal-title":"Epidemiol. Infect."},{"key":"ref_26","first-page":"176","article-title":"School dietitians\u2019 perceptions of potentially hazardous food and inspection of food safety and sanitation","volume":"14","author":"Chung","year":"2008","journal-title":"J. Korean Diet. Assoc."},{"key":"ref_27","first-page":"405","article-title":"A study on the sanitation management status and barriers to HACCP system implementation of school foodservice institutions in Seoul metropolitan area","volume":"13","author":"Kim","year":"2008","journal-title":"Korean J. Commun. Nutr."},{"key":"ref_28","first-page":"38","article-title":"Studies on the knowledge, attitudes, and behavior of mothers toward food hygiene and safety of school food-service programs-Part 1","volume":"19","author":"Kim","year":"2004","journal-title":"J. Food Hyg. Saf."},{"key":"ref_29","first-page":"92","article-title":"The importance of hygiene condition and HACCP system application at school food service","volume":"36","author":"Kim","year":"2003","journal-title":"Food Sci. Ind."},{"key":"ref_30","first-page":"280","article-title":"A study on the evaluation of maternal child health services in public health centers","volume":"13","author":"Kim","year":"2002","journal-title":"J. Korean Commun. Nurs."},{"key":"ref_31","first-page":"51","article-title":"Performance status of sanitary management of school food service in the Jeonnam area","volume":"7","author":"Koh","year":"2004","journal-title":"Korean J. Hum. Ecol."},{"key":"ref_32","first-page":"234","article-title":"A study on the sanitary management of school foodservice operations in Daejeon and Chungnam","volume":"10","author":"Park","year":"2005","journal-title":"Korean J. Commun. Nutr."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jhin.2006.11.011","article-title":"Healthcare-associated infection among residents of long-term care facilities: A cohort and nested case\u2013control study","volume":"65","author":"Eriksen","year":"2007","journal-title":"J. Hosp. Infect."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jhin.2014.11.004","article-title":"Infection control: Beyond the horizon","volume":"89","author":"Gray","year":"2015","journal-title":"J. Hosp. Infect."},{"key":"ref_35","first-page":"105","article-title":"A Proposal of Policy on the Long-term Care System for the Elderly","volume":"17","author":"Park","year":"2007","journal-title":"J. Public Welf. Adm."},{"key":"ref_36","unstructured":"Lee, E. (2009). Current Situation and Policy Implication for the Elderly Long-Term Care Insurance, Health-Welfare Policy Forum."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1017\/S0950268809990379","article-title":"Biennial hyperepidemic shigellosis in an observant Jewish community","volume":"138","author":"Gefen","year":"2010","journal-title":"Epidemiol. Infect."},{"key":"ref_38","first-page":"17","article-title":"Shigellosis winter trends in Milwaukee","volume":"88","author":"Gradus","year":"1989","journal-title":"Wis. Med. J."},{"key":"ref_39","first-page":"73","article-title":"The ecological characteristics of the communities and social interactions of the elderly in rural Korea","volume":"16","author":"Han","year":"2005","journal-title":"Korean J. Commun. Living Sci."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.4315\/0362-028X-68.7.1352","article-title":"Effect of relative humidity on preharvest survival of bacterial and viral pathogens on the surface of cantaloupe, lettuce, and bell peppers","volume":"68","author":"Stine","year":"2005","journal-title":"J. Food Prot."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/15\/10\/2209\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T15:24:46Z","timestamp":1760196286000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/15\/10\/2209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,10]]},"references-count":40,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2018,10]]}},"alternative-id":["ijerph15102209"],"URL":"https:\/\/doi.org\/10.3390\/ijerph15102209","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,10]]}}}