{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:36:51Z","timestamp":1787236611554,"version":"build-2736575974"},"reference-count":51,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T00:00:00Z","timestamp":1547769600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008781","name":"Pomeranian Medical University","doi-asserted-by":"publisher","award":["WNoZ-304-01\/S\/18"],"award-info":[{"award-number":["WNoZ-304-01\/S\/18"]}],"id":[{"id":"10.13039\/501100008781","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>In Poland, in addition to mandatory, free of charge vaccines, listed in the national immunization schedule, numerous self-paid vaccinations are recommended, including meningococcal vaccination (MV). To assess MV uptake among \u22645-year-old children and to evaluate parental knowledge and attitudes regarding invasive meningococcal disease (IMD). A cross-sectional study was conducted in 2018 among 350 parents (mean age: 32.3 years), attending three randomly selected primary care clinics in Szczecin region, Poland. Anonymous questionnaires were administered to the parents by researchers, present at the time the survey was conducted, to self-complete on a voluntary basis. Chi-square or Fisher\u2019s exact for categorical and Mann\u2013Whitney U test for continuous variables. Variables significantly (p &lt; 0.05) associated with \u2018good knowledge\u2019 in the bivariate analysis were used to build a logistic regression model. It was found that the response rate was 93.4%, and MV uptake among children was 29.5%. The main knowledge sources were medical staff and media; 72.5% had ever received information about IMD. Only 18.8% of parents self-assessed their knowledge regarding IMD as good; 61.8% scored &gt;50% in the knowledge test 58.9% knew the mode of transmission, 58.7% recognized the severity of meningitis, and 79.7% knew that bacterial meningitis is a vaccine-preventive disease. Knowledge regarding IMD was higher among parents with higher educational level (OR = 3.37; p = 0.01), from urban facilities (OR = 2.20; p = 0.02), who received previous information about IMD (OR = 2.85; p = 0.01) and self-assessed their knowledge as good (OR = 2.59; p = 0.04). Low MV coverage among children up to five years old and knowledge gaps about IMD call for awareness campaigns which may increase the coverage. Although educational interventions should cover all parents, those from provincial facilities, representing lower education level need special attention.<\/jats:p>","DOI":"10.3390\/ijerph16020265","type":"journal-article","created":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T02:22:23Z","timestamp":1547778143000},"page":"265","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Parental Knowledge about Meningococcal Disease and Vaccination Uptake among 0\u20135 years Old Polish Children"],"prefix":"10.3390","volume":"16","author":[{"given":"Marzena","family":"Drozd-D\u0105browska","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Management, Pomeranian Medical University, Szczecin 71-210, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Topczewska","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Management, Pomeranian Medical University, Szczecin 71-210, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1306-7146","authenticated-orcid":false,"given":"Marcin","family":"Korze\u0144","sequence":"additional","affiliation":[{"name":"Department of Methods of Artificial Intelligence &amp; Applied Mathematics, Westpomeranian University of Technology, Szczecin 71-210, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Sa\u0142acka","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Pomeranian Medical University, Szczecin 70-204, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Ganczak","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Management, Pomeranian Medical University, Szczecin 71-210, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,1,18]]},"reference":[{"key":"ref_1","unstructured":"European Centre for Disease Prevention and Control (2018). Invasive meningococcal disease. ECDC. Annual Epidemiological Report for 2016, ECDC."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1080\/21645515.2017.1313940","article-title":"Meningococcal serogroup B vaccine: Knowledge and acceptability among parents in Italy","volume":"13","author":"Morrone","year":"2017","journal-title":"Hum. Vaccin. Immunother."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"3004","DOI":"10.4161\/21645515.2014.971602","article-title":"Acceptability of meningococcal serogroup B vaccine among parents and health care workers in Italy: A survey","volume":"10","author":"Mameli","year":"2014","journal-title":"Hum. Vaccin. Immunother."},{"key":"ref_4","first-page":"493","article-title":"Menigitis and encephalitis in Poland in 2015","volume":"74","author":"Piotrowska","year":"2017","journal-title":"Przeg. Epidemiol."},{"key":"ref_5","first-page":"129","article-title":"Infectious diseases in Poland in 2016","volume":"72","author":"Czarkowski","year":"2018","journal-title":"Przeg. Epidemiol."},{"key":"ref_6","unstructured":"Konior, R. (2017, November 15). Should Vaccination against Meningococcal Disease Be Mandatory?. Available online: https:\/\/www.mp.pl\/szczepienia\/186451."},{"key":"ref_7","unstructured":"Czajka, H., Dzier\u017canowska-Fangrat, K., Konior, R., Kuchar, E., Stryczy\u0144ska-Kazubska, J., Skoczy\u0144ska, A., Szenborn, L., and Wysocki, J. (2017). Prophylaxis of invasive meningococcal disease in children, adolescents and adults. Med. Prakt., 1, (special edition)."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Van Ravenhorst, M.B., den Hartog, G., van der Klis, F.R.M., van Rooijen, D.M., Sanders, E.A.M., and Berbers, G.A.M. (2018). Induction of salivary antibody levels in Dutch adolescents after immunization with monovalent meningococcal serogroup C or quadrivalent meningococcal serogroup A, C, W and Y conjugate vaccine. PLoS ONE, 13.","DOI":"10.1371\/journal.pone.0191261"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1080\/14760584.2018.1521280","article-title":"An update of clinical experience with the quadrivalent meningococcal ACWY-CRM conjugate vaccine","volume":"17","author":"Keshavan","year":"2018","journal-title":"Expert Rev. Vaccines"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S1473-3099(18)30048-3","article-title":"Immunogenicity and safety of the multicomponent meningococcal B vaccine (4CMenB) in children and adolescents: A systematic review and meta-analysis","volume":"18","author":"Flacco","year":"2018","journal-title":"Lancet Infect. Dis."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/S1473-3099(13)70006-9","article-title":"Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: A qualitative and quantitative assessment","volume":"13","author":"Vogel","year":"2013","journal-title":"Lancet Infect. Dis."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1574-6976.2006.00053.x","article-title":"Vaccination against meningococcal disease in Europe: Review and recommendations for the use of conjugate vaccines","volume":"31","author":"Rotter","year":"2007","journal-title":"FEMS Microbiol. Rev."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"h1486","DOI":"10.1136\/bmj.h1486","article-title":"Teenagers in England to be vaccinated against meningitis group W","volume":"350","author":"Wise","year":"2015","journal-title":"BMJ"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2775","DOI":"10.1016\/S0140-6736(16)31921-3","article-title":"Effectiveness and impact of a reduced infant schedule of 4CMenB vaccine against group B meningococcal disease in England: A national observational cohort study","volume":"388","author":"Parikh","year":"2016","journal-title":"Lancet"},{"key":"ref_15","unstructured":"Chief Sanitary Inspectorate (2018, December 15). Polish National Immunization Program 2019, Available online: https:\/\/gis.gov.pl\/wp-content\/uploads\/2018\/01\/akt.pdf."},{"key":"ref_16","unstructured":"National Institute of Hygiene (2017, November 15). Mandatory Vaccinations in Poland\u2014History and Rationale, Available online: http:\/\/szczepienia.pzh.gov.pl\/en\/stories\/mandatory-vaccinations-in-poland\/."},{"key":"ref_17","unstructured":"(2018, December 17). Reduction of the mandatory vaccination uptake in Poland, Vaccinations in Poland in 2017, Available online: http:\/\/wwwold.pzh.gov.pl\/oldpage\/ epimeld\/index_p.html#05."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"e012851","DOI":"10.1136\/bmjopen-2016-012851","article-title":"UK parents\u2019 attitudes towards meningococcal group B (MenB) vaccination: A qualitative analysis","volume":"7","author":"Jackson","year":"2017","journal-title":"BMJ Open"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1155\/2015\/732464","article-title":"Parents\u2019 and adolescents\u2019 willingness to be vaccinated against serogroup B meningococcal disease during a mass vaccination in Saguenay-Lac-St-Jean (Quebec)","volume":"26","author":"Gagnon","year":"2015","journal-title":"Can. J. Infect. Dis. Med. Microbiol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"3463","DOI":"10.1016\/j.vaccine.2015.05.073","article-title":"Vaccination against serogroup B Neisseria meningitidis: Perceptions and attitudes of parents","volume":"33","author":"Ader","year":"2015","journal-title":"Vaccine"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.vaccine.2013.11.042","article-title":"Parental and community acceptance of the benefits and risks associated with meningococcal B vaccines","volume":"32","author":"Marshall","year":"2014","journal-title":"Vaccine"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00431-012-1904-4","article-title":"Health care providers\u2019 and parents\u2019 attitudes toward administration of new infant vaccines\u2014A multi-national survey","volume":"172","author":"Bakhache","year":"2013","journal-title":"Eur. J. Pediatr."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"7818","DOI":"10.1016\/j.vaccine.2007.08.057","article-title":"More vaccines for children? Parents\u2019 views","volume":"25","author":"Bedford","year":"2007","journal-title":"Vaccine"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"7588","DOI":"10.1016\/j.vaccine.2012.10.037","article-title":"Individual-, family- and community-level determinants of full vaccination coverage among children aged 12\u201323 months in western Kenya","volume":"30","author":"Kawakatsu","year":"2012","journal-title":"Vaccine"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1136\/bmj.332.7553.1312","article-title":"Differences in risk factors for partial and no immunization in the first year of life: Prospective cohort study","volume":"332","author":"Samadi","year":"2006","journal-title":"Br. Med. J."},{"key":"ref_26","unstructured":"(2018, December 08). Available online: https:\/\/stat.gov.pl\/obszary-tematyczne\/roczniki-statystyczne\/roczniki-statystyczne\/rocznik-statystyczny-rzeczypospolitej-polskiej-2017,2,17.html."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"5687","DOI":"10.1016\/j.vaccine.2013.09.056","article-title":"Determinants influencing self-paid vaccination coverage, in 0\u20135 years old Polish children","volume":"31","author":"Ganczak","year":"2013","journal-title":"Vaccine"},{"key":"ref_28","unstructured":"Daniel, W.W. (1995). Biostatistics: A Foundation for Analysis in the Health Sciences, John Wiley & Sons, Inc.. [6th ed.]."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"4165","DOI":"10.1016\/j.vaccine.2015.04.037","article-title":"Measuring vaccine hesitancy: The development of a survey tool","volume":"33","author":"Larson","year":"2015","journal-title":"Vaccine"},{"key":"ref_30","first-page":"MR000008","article-title":"Methods to increase response to postal and electronic questionnaires","volume":"3","author":"Edwards","year":"2009","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1745-6215-11-2","article-title":"Questionnaires in Clinical Trials: Guidelines for Optimal Design and Administration","volume":"11","author":"Edwards","year":"2010","journal-title":"Trials"},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Hosmer, D.W., and Lemeshow, S. (2000). Applied Logistic Regression, John Wiley & Sons Inc.. [2nd ed.].","DOI":"10.1002\/0471722146"},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Venables, W.N., and Ripley, B.D. (2002). Modern Applied Statistics with S, Springer. [4th ed.].","DOI":"10.1007\/978-0-387-21706-2"},{"key":"ref_34","unstructured":"R Development Core Team (2008). R: A Language and Environment for Statistical Computing, R Foundation for Statistical Computing."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"221","DOI":"10.5604\/20834543.1220526","article-title":"Knowledge of immunization among parents of children under two years of age","volume":"22","author":"Pieszka","year":"2016","journal-title":"Med. Og. Nauk. Zdr."},{"key":"ref_36","first-page":"339","article-title":"Realization of immunization schedule with recommended vaccines among children from one general practice","volume":"14","author":"Kozerska","year":"2012","journal-title":"Fam. Med. Prim. Care Rev."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jadohealth.2017.05.016","article-title":"Patterns of use of human papillomavirus and other adolescent vaccines in the United States","volume":"61","author":"Vielot","year":"2017","journal-title":"J. Adolesc. Health"},{"key":"ref_38","first-page":"59","article-title":"Anti-menigococcal and antipneumococcal vaccination determinants: A European literature review","volume":"39","author":"Malerba","year":"2015","journal-title":"Epidemiol. Prev."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"4979","DOI":"10.1016\/j.vaccine.2018.06.044","article-title":"A report on the status of vaccination in Europe","volume":"36","author":"Sheikh","year":"2018","journal-title":"Vaccine"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1179\/2047773214Y.0000000126","article-title":"Global practices of meningococcal vaccine use and impact on invasive disease","volume":"108","author":"Ali","year":"2014","journal-title":"Pathog. Glob. Health"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1080\/20477724.2016.1195072","article-title":"Meningococcal B vaccination: Real-world experience and future perspectives","volume":"110","author":"Kuhdari","year":"2016","journal-title":"Pathog. Glob. Health"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S2352-4642(18)30103-2","article-title":"Safety of multicomponent meningococcal group B vaccine (4CMenB) in routine infant immunisation in the UK: A prospective surveillance study","volume":"2","author":"Bryan","year":"2018","journal-title":"Lancet. Child Adolesc. Health"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1136\/adc.85.5.391","article-title":"Safety of a new conjugate meningococcal C vaccine in infants","volume":"85","author":"Lakshman","year":"2001","journal-title":"Arch. Dis. Child."},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Ganczak, M., Owsianka, B., and Korze\u0144, M. (2018). Factors that predict parental willingness to have their children vaccinated against HPV in a country with low HPV vaccination coverage. Int. J. Environ. Res. Public Health, 15.","DOI":"10.3390\/ijerph15040645"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"6096","DOI":"10.1016\/j.vaccine.2017.09.060","article-title":"Parental perceptions of childhood seasonal influenza vaccination in Singapore: A cross-sectional survey","volume":"35","author":"Low","year":"2017","journal-title":"Vaccine"},{"key":"ref_46","first-page":"27","article-title":"What is parents\u2019 and medical health care specialists knowledge about vaccinations?","volume":"66","author":"Domaradzka","year":"2009","journal-title":"Przegl. Lek."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.1016\/j.vaccine.2014.02.054","article-title":"Community, parental and adolescent awareness and knowledge of meningococcal disease","volume":"32","author":"Wang","year":"2014","journal-title":"Vaccine"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"S37","DOI":"10.1086\/648963","article-title":"Epidemiological Profile of Meningococcal Disease in the United States","volume":"50","author":"Harrison","year":"2010","journal-title":"Clin. Infect. Dis."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"4940","DOI":"10.1016\/j.vaccine.2007.03.032","article-title":"Infant vaccination coverage in 2005 and predictive factors for complete or valid vaccination in Flanders. Belgium: An EPI-survey","volume":"25","author":"Theeten","year":"2007","journal-title":"Vaccine"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1542\/peds.2004-2784","article-title":"Volume matters: Physician practice characteristics and immunization coverage among young children insured through a universal health plan","volume":"117","author":"Guttmann","year":"2006","journal-title":"Pediatrics"},{"key":"ref_51","unstructured":"Gordis, L. (2014). Epidemiology, Sanders. [5th ed.]."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/16\/2\/265\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T12:26:59Z","timestamp":1760185619000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/16\/2\/265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,18]]},"references-count":51,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,1]]}},"alternative-id":["ijerph16020265"],"URL":"https:\/\/doi.org\/10.3390\/ijerph16020265","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,18]]}}}