{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:05:16Z","timestamp":1790798716031,"version":"4.1.0"},"reference-count":29,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T00:00:00Z","timestamp":1553731200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>This study evaluated the prevalence of clinical multidrug-resistant organisms (MDROs) and analyzed correlations between MDROs and patient characteristics in a regional teaching hospital of Taiwan. A retrospective comparative case-control study was conducted from January 2016 to August 2018 by collecting data from 486 hospitalized and non-hospitalized patients (M = 286, F = 200), including patient gender and age, microbial species, and antibiotic susceptibility. The results indicated that at least one MDRO was isolated from 5.3\u20136.3% of patients (p &lt; 0.05), with an average age of 61.08 years. Of the MDROs strains, vancomycin-resistant enterococcus and carbapenem-resistant acinetobacter baumannii increased annually (p &lt; 0.002 and p &lt; 0.012, respectively). Three factors of age (over 60 years), treatment in an intensive care unit (ICU), and specimen category were statistically significant (p &lt; 0.039, p &lt; 0.001 and p &lt; 0.001, respectively) and indicated that elderly patients in an ICU have a higher risk of being infected by MDROs. The outpatients infected by methicillin-resistant staphylococcus aureus (MRSA) were more frequent than inpatients, implying the existence of community-acquired MRSA strains. The results of this study could provide valuable information for the detection and colonization of multidrug-resistant organisms in hospital infection control systems.<\/jats:p>","DOI":"10.3390\/ijerph16071104","type":"journal-article","created":{"date-parts":[[2019,3,29]],"date-time":"2019-03-29T03:38:52Z","timestamp":1553830732000},"page":"1104","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Detection and Colonization of Multidrug Resistant Organisms in a Regional Teaching Hospital of Taiwan"],"prefix":"10.3390","volume":"16","author":[{"given":"Yi-Ping","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Medical Laboratory, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 81267, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching-Chao","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 81267, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renin","family":"Chang","sequence":"additional","affiliation":[{"name":"Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung 84001, Taiwan"},{"name":"Department of Recreation Sports Management, Tajen University, Pingtung 90741, Taiwan"},{"name":"Department of Emergency Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 81362, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen-Min","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 81267, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Hsin","family":"Hung","sequence":"additional","affiliation":[{"name":"Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung 84001, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tung-Nan","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Science and Biotechnology, Chung-Hwa University of Medical Technology, Tainan 71703, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9630-134X","authenticated-orcid":false,"given":"Chien-Sen","family":"Liao","sequence":"additional","affiliation":[{"name":"Institute of Biotechnology and Chemical Engineering, I Shou University, Kaohsiung 84001, Taiwan"},{"name":"Department of Civil and Ecological Engineering, I Shou University, Kaohsiung 84001, Taiwan"},{"name":"Department of Food and Human Health Sciences, Osaka City University, Osaka 558-8585, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,3,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Boldt, A.C., Schwab, F., Rohde, A.M., Kola, A., Bui, M.T., M\u00e4rtin, N., Kipnis, M., Schr\u00f6der, C., Leistner, R., and WiesePosselt, M. 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