{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:50:48Z","timestamp":1760403048356,"version":"build-2065373602"},"reference-count":61,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T00:00:00Z","timestamp":1579046400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Generalitat Valenciana (Concelleria D\u2019 Educaci\u00f3, Investigaci\u00f3 Cultura I Esport)","award":["GV\/2017\/112."],"award-info":[{"award-number":["GV\/2017\/112."]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Celiac disease (CD) is an immunological disorder that mainly affects the small intestine, generating an inflammatory process in response to the presence of gluten (a protein). Autoimmune diseases are part of a group of diseases that are difficult to diagnose without a specific protocol or consensus to detect them due to the number of symptoms and diseases with which it has a relationship. Therefore, the aim of this review was to analyze the diagnostic tools of CD used in middle-aged women, to compare the use and effectiveness of the different tools, and to propose a strategy for the use of the tools based on the results found in the literature. The present research followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. The search was conducted in the following databases: Scielo, PubMed, Web of Science, and Worldwide Science org. In the initial literature search, 2004 titles and relevant abstracts were found. Among them, 687 were duplicates, leaving 1130 articles. Based on the inclusion criteria, only 41 articles passed the selection process; 4 main types of analyses appear in the studies: blood tests, questionnaires, clinical history, and biopsy. It can be said that none of the analyses have a 100% reliability since most of them can present false negatives; therefore, the best way to diagnose celiac disease up to now is through a combination of different tests (Immunoglobulin A and small intestinal biopsy).<\/jats:p>","DOI":"10.3390\/ijerph17020539","type":"journal-article","created":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T10:30:27Z","timestamp":1579084227000},"page":"539","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Tools Used to Measure the Physical State of Women with Celiac Disease: A Review with a Systematic Approach"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4747-3465","authenticated-orcid":false,"given":"Alejandro","family":"Mart\u00ednez-Rodr\u00edguez","sequence":"first","affiliation":[{"name":"Faculty of Sciences, University of Alicante, 03690 Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela Alejandra","family":"Loaiza-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Faculty of Sports, Catholic University of Murcia (UCAM), 30107 Murcia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"S\u00e1nchez-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"School of Sport and Science, European University of Madrid, 28670 Madrid, Spain"},{"name":"IGOID Research Group, University of Castilla de la Mancha, 13071 Castilla la Mancha, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1624-5013","authenticated-orcid":false,"given":"Pablo J.","family":"Marcos-Pardo","sequence":"additional","affiliation":[{"name":"Faculty of Sports, Catholic University of Murcia (UCAM), 30107 Murcia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1330-2388","authenticated-orcid":false,"given":"Soledad","family":"Prats","sequence":"additional","affiliation":[{"name":"Faculty of Sciences, University of Alicante, 03690 Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6126-5289","authenticated-orcid":false,"given":"Fernando","family":"Alacid","sequence":"additional","affiliation":[{"name":"Department of Education, Health Research Centre, University of Almer\u00eda, 04120 Almer\u00eda, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2496-2426","authenticated-orcid":false,"given":"Jacobo A.","family":"Rubio-Arias","sequence":"additional","affiliation":[{"name":"LFE Research Group, Department of Health and Human Performance, Faculty of Physical Activity and Sport Sciences, Universidad Polit\u00e9cnica de Madrid (UPM), 28040 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,1,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"5810","DOI":"10.3748\/wjg.v16.i46.5810","article-title":"Reproductive changes associated with celiac disease","volume":"16","author":"Freeman","year":"2010","journal-title":"World J. 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