{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:30:48Z","timestamp":1787495448392,"version":"build-2736575974"},"reference-count":33,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2020,1,20]],"date-time":"2020-01-20T00:00:00Z","timestamp":1579478400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Shift work is considered a risk factor for some health problems. This study aimed to determine whether night shift work is a significant factor for breast cancer risk. The case\u2013control study was conducted from 2015\u20132019 in the \u0141\u00f3d\u017a region. The case group included 494 women diagnosed with malignant breast cancer; the control group included 515 healthy women. The research tool was an anonymous questionnaire. In the case group, the percentage of women working shift work was 51.9%, whereas in the control group, it was 34.1% (OR = 2.08 (95% CI: 1.61; 2.69)). A more insightful examination of shift work showed that only night work has a significant impact on breast cancer (OR = 2.61 (95% CI: 1.94; 3.53)). Even after considering the effect of other possible cancer factors (like high BMI, smoking, early menstruation, late menopause, pregnancy history, age, place of living, education), the odds of developing cancer were twice as high in the group of shift workers (OR = 2.20 (95% CI: 1.57; 3.08)). Considering a significantly higher risk of cancer among people working at night and a high percentage of such employees in Poland, the government should consider special action in the prophylactic treatment of cancers.<\/jats:p>","DOI":"10.3390\/ijerph17020659","type":"journal-article","created":{"date-parts":[[2020,1,20]],"date-time":"2020-01-20T04:27:09Z","timestamp":1579494429000},"page":"659","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Night Shift Work\u2014A Risk Factor for Breast Cancer"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3631-5082","authenticated-orcid":false,"given":"Marta","family":"Szkiela","sequence":"first","affiliation":[{"name":"Department of Hygiene and Epidemiology, Department of Hygiene and Health Promotion; Faculty of Health Sciences, Medical University of Lodz, 90-647 \u0141\u00f3d\u017a, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0138-6991","authenticated-orcid":false,"given":"Ewa","family":"Kuside\u0142","sequence":"additional","affiliation":[{"name":"Department of Spatial Econometrics, Faculty of Economics and Sociology, University of Lodz, 90-255 \u0141\u00f3d\u017a, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Makowiec-D\u0105browska","sequence":"additional","affiliation":[{"name":"Department of Work Physiology and Ergonomics, Nofer Institute of Occupational Medicine in \u0141\u00f3d\u017a, 91-348 \u0141\u00f3d\u017a, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota","family":"Kaleta","sequence":"additional","affiliation":[{"name":"Department of Hygiene and Epidemiology, Department of Hygiene and Health Promotion; Faculty of Health Sciences, Medical University of Lodz, 90-647 \u0141\u00f3d\u017a, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,1,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/s10552-005-9015-4","article-title":"Biological clocks and shift work: Circadian dysregulation and potential long-term effects","volume":"17","author":"Haus","year":"2006","journal-title":"Cancer Causes Control"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1093\/occmed\/kqg048","article-title":"Health disorders of shift workers","volume":"53","author":"Knutsson","year":"2003","journal-title":"Occup. Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1093\/occmed\/kqg045","article-title":"Shift work and occupational medicine: An overview","volume":"53","author":"Costa","year":"2003","journal-title":"Occup. Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1038\/bjc.2013.544","article-title":"The association between different night shift work factors and breast cancer: A case\u2013control study","volume":"109","author":"Fritschi","year":"2013","journal-title":"Br. J. Cancer"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/aje\/kwj232","article-title":"Prospective cohort study of the risk of prostate cancer among rotating-shift workers: Findings from the Japan Collaborative Cohort Study","volume":"164","author":"Kubo","year":"2006","journal-title":"Am. J. Epidemiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"10618","DOI":"10.1158\/0008-5472.CAN-07-2485","article-title":"Nightshift work and the risk of endometrial cancer","volume":"67","author":"Viswanathan","year":"2007","journal-title":"Cancer Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1093\/jnci\/95.11.825","article-title":"Night-shift workers and the risk ofcolorectal cancer in the nurses\u2019 health study","volume":"95","author":"Schernhammer","year":"2003","journal-title":"J. Natl. Cancer Inst."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1002\/ijc.23566","article-title":"Night-time work predisposes to non-Hodgkin lymphoma","volume":"123","author":"Lahti","year":"2008","journal-title":"Int. J. Cancer"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/j.1600-079X.2007.00473.x","article-title":"The dark side of light at night: Physiological, epidemiological, and ecological consequences","volume":"43","author":"Navara","year":"2007","journal-title":"J. Pineal Res."},{"key":"ref_10","first-page":"22","article-title":"Melatonina\u2014Stale odkrywany hormon","volume":"4","author":"Szanecki","year":"2006","journal-title":"Ginekol. Prakt."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S1054-3589(08)61169-2","article-title":"Photic and neural control of indoleamine metabolism in the rat pineal gland","volume":"6","author":"Axelrod","year":"1968","journal-title":"Adv. Pharmacol."},{"key":"ref_12","first-page":"313","article-title":"Oncostatic effects of the pineal gland","volume":"8","author":"Kerenyi","year":"1990","journal-title":"Drug Metab. Drug Interact."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.pneurobio.2008.04.001","article-title":"Physiological effects of melatonin: Role of melatonin receptors and signal transduction pathways","volume":"85","author":"Trakht","year":"2008","journal-title":"Prog Neurobiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s10549-007-9617-5","article-title":"Melatonin, environmental light, and breast cancer","volume":"108","author":"Srinivasan","year":"2008","journal-title":"Breast Cancer Res. Treat."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/S0140-6736(78)92018-4","article-title":"Pineal gland and breast cancer","volume":"2","author":"Cohen","year":"1978","journal-title":"Lancet"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1093\/oxfordjournals.aje.a114569","article-title":"Electric power use and breast cancer: A hypothesis","volume":"125","author":"Stevens","year":"1987","journal-title":"Am. J. Epidemiol."},{"key":"ref_17","unstructured":"International Agency for Research on Cancer (2007, January 2\u20139). Painting, firefighting, and shiftwork. Proceedings of the IARC Monographs Working Group on the Evaluation of Carcinogenic Risks to Humans, Lyon, France."},{"key":"ref_18","first-page":"701","article-title":"Odpowied\u017a autor\u00f3w na list do redakcji dotycz\u0105cy artyku\u0142u Model dzia\u0142a\u0144 profilaktycznych zintegrowany z opiek\u0105 profilaktyczn\u0105 nad pracownikami\u2014Zapobieganie niekt\u00f3rym typom nowotwor\u00f3w w\u015br\u00f3d kobiet [Authors reply to the editor\u2019s letter regarding the article The prophylactic operational model integrated with occupational healthcare\u2014Prophylactic of some types of cancers among women]","volume":"69","author":"Wiszsniewska","year":"2018","journal-title":"Medycyna Pracy"},{"key":"ref_19","first-page":"325","article-title":"Night Shift Work and Risk of Breast Cancer","volume":"4","author":"Hansen","year":"2017","journal-title":"Environ. Health Rep."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1093\/aje\/kws422","article-title":"Self reported sleep duration, sleep quality, and breast cancer risk in a populatio based case-control study","volume":"177","author":"Girschik","year":"2013","journal-title":"Am. J. Epidemiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1002\/ijc.27669","article-title":"Night work and breast cancer: A population-based case-control study in France (The CECILE study)","volume":"132","author":"Menegaux","year":"2013","journal-title":"Int. J. Cancer"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1136\/oemed-2013-101482","article-title":"Increased risk of breast cancer associated with long term shift work in Canada","volume":"70","author":"Grundy","year":"2013","journal-title":"Occup. Environ. Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"djw169","DOI":"10.1093\/jnci\/djw169","article-title":"Night shift work and breast cancer incidence: Three prospective studies and meta-analysis of published studies","volume":"108","author":"Travis","year":"2016","journal-title":"J. Natl. Cancer Inst."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"134","DOI":"10.5271\/sjweh.2890","article-title":"Night work and breast cancer\u2014Results from the German GENICA study","volume":"36","author":"Pesch","year":"2010","journal-title":"Scand. J. Work Environ. Health"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"e008127","DOI":"10.1136\/bmjopen-2015-008127","article-title":"Night work and breast cancer in women: A Swedish cohort study","volume":"5","author":"Knutsson","year":"2015","journal-title":"BMJ Open"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1093\/aje\/kwq029","article-title":"Night-shift work and breast cancer risk in a cohort of Chinese women","volume":"171","author":"Pronk","year":"2010","journal-title":"Am. J. Epidemiol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s10654-014-9938-8","article-title":"Night work and breast cancer risk in a general population prospective cohort study in The Netherlands","volume":"29","author":"Koppes","year":"2014","journal-title":"Eur. J. Epidemiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s10549-013-2433-1","article-title":"Nightshift work and risk of breast cancer: A systematic review and meta-analysis","volume":"138","author":"Kamdar","year":"2013","journal-title":"Breast Cancer Res. Treat."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1158\/1055-9965.EPI-17-0221","article-title":"Night Shift Work Increases the Risks of Multiple Primary Cancers in Women: A Systematic Review and Meta-analysis of 61 Articles","volume":"27","author":"Yuan","year":"2018","journal-title":"Cancer Epidemiol. Biomark. Prev."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1007\/s10552-005-9006-5","article-title":"Risk of breast cancer after night- and shift work: Current evidence and ongoing studies in Denmark","volume":"17","author":"Hansen","year":"2006","journal-title":"Cancer Causes Control"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1093\/jnci\/93.20.1563","article-title":"Rotating night shift sand risk of breast cancer in women participating in the nurses\u2019 health study","volume":"93","author":"Schernhammer","year":"2001","journal-title":"J. Natl. Cancer Inst."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1097\/01.ede.0000190539.03500.c1","article-title":"Night work and risk of breast cancer","volume":"17","author":"Schernhammer","year":"2006","journal-title":"Epidemiology"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1093\/aje\/kwj211","article-title":"Shift Work, Light at Night, and Breast Cancer on Long Island, New York","volume":"164","author":"Schoenfeld","year":"2006","journal-title":"Am. J. Epidemiol."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/17\/2\/659\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T13:44:06Z","timestamp":1760363046000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/17\/2\/659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,20]]},"references-count":33,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,1]]}},"alternative-id":["ijerph17020659"],"URL":"https:\/\/doi.org\/10.3390\/ijerph17020659","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,20]]}}}