{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T13:01:33Z","timestamp":1782910893048,"version":"3.54.5"},"reference-count":24,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T00:00:00Z","timestamp":1583452800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>(1) Background: Cervical cancer is one of the most common cancers in Korean women. This study was performed to discover the utility of HPV (Human Papillomavirus) testing in screening of cervical lesions and to provide the prevalence of HPV and the genotype distribution in a single center of Korea. (2) Methods: A total of 15,141 women who underwent both HPV testing and cervical cytology were enrolled in this retrospective medical record review study. (3) Results: HPV testing showed higher sensitivity than cytology for the detection of histological high-grade squamous lesions. Furthermore, the sensitivity and specificity of HPV testing varied depending on the method used. The BD Onclarity\u2122 HPV assay had higher sensitivity (90%) than the MyHPV CHIP\u2122 kit (all types of HPV: 82%; high-risk HPV: 76%) for high-grade squamous lesions. A combination of MyHPV CHIP\u2122 and cytology detected 90.9% (30\/33) of histological high-grade squamous lesions. A combination of BD Onclarity\u2122 HPV assay and cytology detected 96.55% (84\/87) of histological high-grade squamous lesions. In addition, HPV prevalence and genotype distribution were different depending on the HPV testing method used. (4) Conclusion: HPV testing showed higher sensitivity than cytology, but the sensitivity and specificity of HPV testing had variation depending on the method used.<\/jats:p>","DOI":"10.3390\/ijerph17051726","type":"journal-article","created":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T09:26:41Z","timestamp":1583486801000},"page":"1726","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Utility of Human Papillomavirus Testing for Cervical Cancer Screening in Korea"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4244-1985","authenticated-orcid":false,"given":"Mee-seon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Pathology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 51353, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Hee","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pathology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 51353, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moon-il","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Pathology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 51353, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Seok","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pathology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 51353, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kisu","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pathology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 51353, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mee Sook","family":"Roh","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dong-A University College of Medicine, Busan 49201, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyoun Wook","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pathology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 51353, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,3,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"431","DOI":"10.4143\/crt.2019.139","article-title":"Prediction of Cancer Incidence and Mortality in Korea, 2019","volume":"51","author":"Jung","year":"2019","journal-title":"Cancer Res. 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