{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:15:55Z","timestamp":1792804555492,"version":"4.5.0"},"reference-count":43,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2020,4,10]],"date-time":"2020-04-10T00:00:00Z","timestamp":1586476800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministerio de Ciencia e Innovaci\u00f3n, Convocatoria de Ayudas I+D 2008, Proyectos de Investigaci\u00f3n Fundamental No Orientada del VI Plan de Investigaci\u00f3n Nacional 2008-2011","award":["DEP2008-06354-C04-01"],"award-info":[{"award-number":["DEP2008-06354-C04-01"]}],"id":[{"id":"https:\/\/ror.org\/05r0vyz12","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Studies with overweight people are a priority in order to observe the effect of the timing of intervention on pre-obesity people. The aim was to compare different physical activity programs plus an individualized hypocaloric diet on body composition in overweight subjects. A randomized controlled clinical trial was carried out in overweight adults with no history of relevant illness. Primary outcome was total fat mass (TFM). Participants were allocated into four activity programs with equal intensity and volume of exercise for 22 weeks: strength training (S), endurance training (E), strength + endurance training (SE), and \u2018adhering to physical activity recommendations\u2019 (C). Participants followed a diet with 25% less energy (50%\u201355% carbohydrates, 30%\u201335% fat) measured by accelerometer. Variables were assessed at baseline and at the end of the intervention. Body composition was measured by dual-energy X-ray absorptiometry. One hundred nineteen from 205 subjects were randomized in the four exercise groups (S = 30\/E = 30\/SE = 30\/C = 29) and 84 participants (36 men\/48 women) ended the intervention (S = 19\/E = 25\/SE = 22\/C = 18). At the end of the experiment, all groups except C increased their total physical activity (S = 1159 \u00b1 1740; E = 1625 \u00b1 1790; SE = 1699 \u00b1 2516; C = 724 \u00b1 1979 MET-min\/week). Using an ANOVA-test, improvements were observed in body weight (S = \u22124.6 \u00b1 4.5; E = \u22126.6 \u00b1 4.6; SE = \u22128.5 \u00b1 2.8; C = \u22126.1 \u00b1 5.6 kg, p = 0.059) and TFM (S = \u22124.24 \u00b1 2.02; E = \u22124.74 \u00b1 2.96; SE = \u22126.74 \u00b1 3.27; C = \u22123.94 \u00b1 4.18%; p &lt; 0.05). The main conclusion was that there were no adverse events. Strength and endurance training with a balanced, individualized hypocaloric diet was the most effective at reducing weight loss and fat mass in overweight subjects. Trial registration: NCT01116856.<\/jats:p>","DOI":"10.3390\/ijerph17072596","type":"journal-article","created":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T04:45:31Z","timestamp":1586753131000},"page":"2596","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Strength plus Endurance Training and Individualized Diet Reduce Fat Mass in Overweight Subjects: A Randomized Clinical Trial"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1631-8182","authenticated-orcid":false,"given":"Pedro J.","family":"Benito","sequence":"first","affiliation":[{"name":"LFE Research Group, Department of Health and Human Performance, Faculty of Physical Activity and Sport Science-INEF, Universidad Polit\u00e9cnica de Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9310-1545","authenticated-orcid":false,"given":"Bricia","family":"L\u00f3pez-Plaza","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Hospital La Paz Health Research Institute (IdiPAZ), La Paz University Hospital, 28046 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6826-0181","authenticated-orcid":false,"given":"Laura M.","family":"Bermejo","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Hospital La Paz Health Research Institute (IdiPAZ), La Paz University Hospital, 28046 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4871-8682","authenticated-orcid":false,"given":"Ana B.","family":"Peinado","sequence":"additional","affiliation":[{"name":"LFE Research Group, Department of Health and Human Performance, Faculty of Physical Activity and Sport Science-INEF, Universidad Polit\u00e9cnica de Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4119-0002","authenticated-orcid":false,"given":"Roc\u00edo","family":"Cupeiro","sequence":"additional","affiliation":[{"name":"LFE Research Group, Department of Health and Human Performance, Faculty of Physical Activity and Sport Science-INEF, Universidad Polit\u00e9cnica de Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Butrague\u00f1o","sequence":"additional","affiliation":[{"name":"LFE Research Group, Department of Health and Human Performance, Faculty of Physical Activity and Sport Science-INEF, Universidad Polit\u00e9cnica de Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3217-7786","authenticated-orcid":false,"given":"Miguel A.","family":"Rojo-Tirado","sequence":"additional","affiliation":[{"name":"LFE Research Group, Department of Health and Human Performance, Faculty of Physical Activity and Sport Science-INEF, Universidad Polit\u00e9cnica de Madrid, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7578-241X","authenticated-orcid":false,"given":"Domingo","family":"Gonz\u00e1lez-Lamu\u00f1o","sequence":"additional","affiliation":[{"name":"Laboratory of Pediatrics, Department of Medical and Surgery Sciences, Faculty of Medicine, University of Cantabria, Marqu\u00e9s de Valdecilla Biomedical Research Institute (IDIVAL), 39011 Santander, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"G\u00f3mez-Candela","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Hospital La Paz Health Research Institute (IdiPAZ), La Paz University Hospital, 28046 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the PRONAF Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,4,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1056\/NEJMoa055643","article-title":"Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old","volume":"355","author":"Adams","year":"2006","journal-title":"N. 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