{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T11:27:56Z","timestamp":1774351676573,"version":"3.50.1"},"reference-count":44,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2020,4,29]],"date-time":"2020-04-29T00:00:00Z","timestamp":1588118400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>This study examined the association between energy drink consumption and substance use among adolescents and tested whether sex and\/or grade level (i.e., middle vs. high school) moderate the association. Data were derived from the 2017 Ontario Student Drug Use and Health Survey, a representative survey of students in 7th to 12th grade. Analyses included 10,662 students who self-reported information on energy drink consumption and substance use. Poisson regression models were used with adjustments for important covariates. Energy drink consumption was associated with tobacco cigarette smoking (incidence rate ratio (IRR): 3.74; 95% confidence interval (CI): 3.22\u20134.35), cannabis use (IRR: 2.90; 95% CI: 2.53\u20133.32), binge drinking (IRR: 2.46; 95% CI: 2.05\u20132.96), opioid use (IRR: 2.23; 95% CI: 1.85\u20132.68), and alcohol use (IRR: 1.31; 95% CI: 1.26\u20131.36). The associations of energy drink consumption with tobacco cigarette smoking, cannabis use, and alcohol consumption were modified by grade level (two-way interaction terms p &lt; 0.05). The association between energy drink consumption and substance use was generally much stronger among middle school students compared with high school students. The findings suggest that middle school students may be more vulnerable to the negative effects of energy drinks in relation with substance use.<\/jats:p>","DOI":"10.3390\/ijerph17093110","type":"journal-article","created":{"date-parts":[[2020,4,29]],"date-time":"2020-04-29T13:23:45Z","timestamp":1588166625000},"page":"3110","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Energy Drink Consumption and Substance Use among Middle and High School Students"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7195-8086","authenticated-orcid":false,"given":"Hugues","family":"Sampasa-Kanyinga","sequence":"first","affiliation":[{"name":"School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON K1G 5Z3, Canada"},{"name":"Healthy Active Living and Obesity Research Group, Children\u2019s Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lydie","family":"Masengo","sequence":"additional","affiliation":[{"name":"Department of Psychology, Carleton University, Ottawa, ON K1S 5B6, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayley A.","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, ON M5S 2S1, Canada"},{"name":"Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5T 3M7, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5607-5736","authenticated-orcid":false,"given":"Jean-Philippe","family":"Chaput","sequence":"additional","affiliation":[{"name":"School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON K1G 5Z3, Canada"},{"name":"Healthy Active Living and Obesity Research Group, Children\u2019s Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,4,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1479-5868-1-3","article-title":"Food advertising and marketing directed at children and adolescents in the US","volume":"1","author":"Story","year":"2004","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1541-4337.2010.00111.x","article-title":"Energy drinks: An assessment of their market size, consumer demographics, ingredient profile, functionality, and regulations in the United States","volume":"9","author":"Heckman","year":"2010","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1057\/jphp.2013.6","article-title":"Energy drinks: An emerging public health hazard for youth","volume":"34","author":"Pomeranz","year":"2013","journal-title":"J. Public Health Policy"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.cpem.2007.12.002","article-title":"Energy drinks: The new eye-opener for adolescents","volume":"9","author":"Babu","year":"2008","journal-title":"Clin. Pediatr. Emerg. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"46","DOI":"10.5694\/mja11.10838","article-title":"Energy drinks: Health risks and toxicity","volume":"196","author":"Gunja","year":"2012","journal-title":"Med. J. Austr."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.drugalcdep.2008.08.001","article-title":"Caffeinated energy drinks\u2014A growing problem","volume":"99","author":"Reissig","year":"2009","journal-title":"Drug Alcohol. Depend."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.neubiorev.2009.01.001","article-title":"Caffeine use in children: What we know, what we have left to learn, and why we should worry","volume":"33","author":"Temple","year":"2009","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1542\/peds.2011-0965","article-title":"Clinical Report\u2014Sports drinks and energy drinks for children and adolescents: Are they appropriate","volume":"127","author":"Pediatrics","year":"2011","journal-title":"Pediatrics"},{"key":"ref_9","unstructured":"Government of Canada (2015). Caffeinated energy drinks, Foods Marketed as Natural Health Products."},{"key":"ref_10","unstructured":"Boak, A., Hamilton, H.A., Adlaf, E.M., and Mann, R.E. (2017). Drug Use among Ontario Students, 1977\u20132017: Detailed Findings from the Ontario Student Drug Use and Health Survey (OSDUHS) (CAMH Research Document Series No. 46), Centre for Addiction and Mental Health."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Singh, G.M., Micha, R., Khatibzadeh, S., Shi, P., Lim, S., Andrews, K.G., Engell, R.E., Ezzati, M., Mozaffarian, D., and Global Burden of Diseases Nutrition and Chronic Diseases Expert Group (NutriCoDE) (2015). Global, Regional, and national consumption of sugar-sweetened beverages, fruit juices, and milk: A systematic assessment of beverage intake in 187 countries. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0124845"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1177\/1367493517731948","article-title":"Behavioural correlates of energy drink consumption among adolescents: A review of the literature","volume":"21","author":"Dawodu","year":"2017","journal-title":"J. Child Health Care"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.appet.2019.04.016","article-title":"Energy drink consumption among German adolescents: Prevalence, correlates, and predictors of initiation","volume":"139","author":"Galimov","year":"2019","journal-title":"Appetite"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/jpc.13708","article-title":"Energy drink consumption among New Zealand adolescents: Associations with mental health, health risk behaviours and body size","volume":"54","author":"Utter","year":"2018","journal-title":"J. Paediatr. Child Health"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.ypmed.2014.01.019","article-title":"An emerging adolescent health risk: Caffeinated energy drink consumption patterns among high school students","volume":"62","author":"Azagba","year":"2014","journal-title":"Prev. Med."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1097\/01.ADM.0000435322.07020.53","article-title":"Energy drinks, soft drinks, and substance use among United States secondary school students","volume":"8","author":"Johnston","year":"2014","journal-title":"J. Addict. Med."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"E19","DOI":"10.9778\/cmajo.20120017","article-title":"The consumption of alcohol mixed with energy drinks: Prevalence and key correlates among Canadian high school students","volume":"1","author":"Azagba","year":"2013","journal-title":"CMAJ Open"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"100865","DOI":"10.1016\/j.pmedr.2019.100865","article-title":"Youth consumption of alcohol mixed with energy drinks in Canada: Assessing the role of energy drinks","volume":"14","author":"Doggett","year":"2019","journal-title":"Prev. Med. Rep."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1542\/peds.2009-3592","article-title":"Health effects of energy drinks on children, adolescents, and young adults","volume":"127","author":"Seifert","year":"2011","journal-title":"Pediatrics"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.nut.2017.11.013","article-title":"Sleep duration and consumption of sugar-sweetened beverages and energy drinks among adolescents","volume":"48","author":"Hamilton","year":"2018","journal-title":"Nutrition"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Sampasa-Kanyinga, H., and Chaput, J.-P. (2016). Consumption of sugar-sweetened beverages and energy drinks and adherence to physical activity and screen time recommendations among adolescents. Int. J. Adolesc. Med. Health, 29.","DOI":"10.1515\/ijamh-2015-0098"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"e496","DOI":"10.17269\/cjph.104.3998","article-title":"Energy drink consumption and associations with demographic characteristics, drug use and injury among adolescents","volume":"104","author":"Hamilton","year":"2013","journal-title":"Can. J. Public Health"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Degirmenci, N., Fossum, I.N., Strand, T.A., Vaktskjold, A., and Holten-Andersen, M.N. (2018). Consumption of energy drinks among adolescents in Norway: A cross-sectional study. BMC Public Health, 18.","DOI":"10.1186\/s12889-018-6236-5"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Frayon, S., Wattelez, G., Cherrier, S., Cavaloc, Y., Lerrant, Y., and Galy, O. (2019). Energy drink consumption in a pluri-ethnic population of adolescents in the Pacific. PLoS ONE, 14.","DOI":"10.1371\/journal.pone.0214420"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"e010380","DOI":"10.1136\/bmjopen-2015-010380","article-title":"Consumption of energy drinks by children and young people: A rapid review examining evidence of physical effects and consumer attitudes","volume":"6","author":"Visram","year":"2016","journal-title":"BMJ Open"},{"key":"ref_26","unstructured":"Mattson, M.E. (2013). Update on Emergency Department Visits Involving Energy Drinks: A Continuing Public Health Concern, The CBHSQ Report."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.pmedr.2016.03.014","article-title":"Energy drink consumption and substance use risk in middle school students","volume":"3","author":"Mann","year":"2016","journal-title":"Prev. Med. Rep."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1017\/S1368980007219652","article-title":"The effects of a middle-school healthy eating intervention on adolescents\u2019 fat and fruit intake and soft drinks consumption","volume":"10","author":"Haerens","year":"2007","journal-title":"Public Health Nutr."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1177\/0193841X09337228","article-title":"The impact of active consent procedures on nonresponse and nonresponse error in youth survey data: Evidence from a new experiment","volume":"33","author":"Courser","year":"2009","journal-title":"Eval. Rev."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1177\/0193841X03259549","article-title":"How does active parental consent influence the findings of drug-use surveys in schools?","volume":"28","author":"White","year":"2004","journal-title":"Eval. Rev."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"E31","DOI":"10.1542\/peds.108.2.e31","article-title":"Adolescents\u2019 perceptions of social status: Development and evaluation of a new indicator","volume":"108","author":"Goodman","year":"2001","journal-title":"Pediatrics"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1093\/aje\/kwh090","article-title":"A modified poisson regression approach to prospective studies with binary data","volume":"159","author":"Zou","year":"2004","journal-title":"Am. J. Epidemiol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1177\/1536867X0900900201","article-title":"Methods for estimating adjusted risk ratios","volume":"9","author":"Cummings","year":"2009","journal-title":"Stata J."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.puhe.2018.08.001","article-title":"Use of social networking sites, electronic cigarettes, and waterpipes among adolescents","volume":"164","author":"Hamilton","year":"2018","journal-title":"Public Health"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1017\/S0007114515003566","article-title":"Associations between the use of social networking sites and unhealthy eating behaviours and excess body weight in adolescents","volume":"114","author":"Chaput","year":"2015","journal-title":"Br. J. Nutr."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.puhe.2016.05.005","article-title":"Use of social networking sites and alcohol consumption among adolescents","volume":"139","author":"Chaput","year":"2016","journal-title":"Public Health"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.ajp.2015.05.001","article-title":"Energy-drink consumption and its relationship with substance use and sensation seeking among 10th grade students in Istanbul","volume":"15","author":"Evren","year":"2015","journal-title":"Asian J. Psychiatr."},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Assanangkornchai, S., Li, J., McNeil, E., and Saingam, D. (2018). Clusters of alcohol and drug use and other health-risk behaviors among Thai secondary school students: A latent class analysis. BMC Public Health, 18.","DOI":"10.1186\/s12889-018-6205-z"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1097\/PEC.0000000000000644","article-title":"Reasons for Energy Drink Use and Reported Adverse Effects Among Adolescent Emergency Department Patients","volume":"33","author":"Nordt","year":"2017","journal-title":"Pediatr. Emerg. Care"},{"key":"ref_40","unstructured":"US Department of Health and Human Services (2013). Substance Abuse and Mental Health Services Administration: Center for Behavioral Health Statistics and Quality, The DAWN Report: Update on Emergency Department Visits Involving Energy Drinks: A Continuing Public Health Concern."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1111\/j.1530-0277.2006.00070.x","article-title":"Effects of energy drink ingestion on alcohol intoxication","volume":"30","author":"Ferreira","year":"2006","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/nure.12127","article-title":"Energy drinks mixed with alcohol: What are the risks?","volume":"72","author":"Marczinski","year":"2014","journal-title":"Nutr. Rev."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.annemergmed.2011.06.015","article-title":"Adolescents and young adults presenting to the emergency department intoxicated from a caffeinated alcoholic beverage: A case series","volume":"59","author":"Cleary","year":"2012","journal-title":"Ann. Emerg. Med."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/s12937-016-0204-7","article-title":"Association between energy drink intake, sleep, stress, and suicidality in Korean adolescents: Energy drink use in isolation or in combination with junk food consumption","volume":"15","author":"Park","year":"2016","journal-title":"Nutr. J."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/17\/9\/3110\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T13:24:08Z","timestamp":1760361848000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/17\/9\/3110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,29]]},"references-count":44,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2020,5]]}},"alternative-id":["ijerph17093110"],"URL":"https:\/\/doi.org\/10.3390\/ijerph17093110","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,29]]}}}