{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T04:51:19Z","timestamp":1770526279395,"version":"3.49.0"},"reference-count":24,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2020,5,29]],"date-time":"2020-05-29T00:00:00Z","timestamp":1590710400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Aim: To analyze a single-centre experience in feminizing genitoplasty in virilized girls with congenital adrenal hyperplasia (CAH). Methods: Review of medical records of all 46, XX CAH patients undergoing single stage feminizing genitoplasty between 2003 and 2018 was performed. Results: A total of 31 girls aged from 4 months to 10 years were included in the study. The majority (n = 26\/31, 84%) were operated before 2 years of age (median 8 months). External virilization was rated as Prader 3 (n = 7\/31), Prader 4 (n = 21\/31) and Prader 5 (n = 3\/31). The urethrovaginal confluence location was low in 19 and high in 12 girls with a percentage distribution similar in Prader 4 and 5 (p &gt; 0.05) but significantly different in Prader 3 (p = 0.017). The follow-up ranged from 12 months to 15 years. All parents assessed the cosmetic result as satisfactory. Perioperative complications occurred in two patients and included rectal injury (n = 1\/31) and prolonged bleeding (n = 1\/31). Three patients developed late complications including labial atheromas (n = 2\/31) and vaginal stricture requiring surgical dilatation (n = 1\/31). Low confluence did not decrease the risk of complications. Conclusions: Early feminizing genitoplasty in girls with congenital adrenal hyperplasia, irrespective of virilization severity, gives satisfactory cosmetic results and is characterized by low and acceptable surgical risk. Nevertheless, the most important determinant of the effectiveness of such management would be future patients\u2019 satisfaction.<\/jats:p>","DOI":"10.3390\/ijerph17113852","type":"journal-article","created":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T11:49:21Z","timestamp":1591012161000},"page":"3852","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Early Feminizing Genitoplasty in Girls with Congenital Adrenal Hyperplasia (CAH)\u2014Analysis of Unified Surgical Management"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6743-9833","authenticated-orcid":false,"given":"Grzegorz","family":"Kudela","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery and Urology, Medical University of Silesia, 40-752 Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9309-4741","authenticated-orcid":false,"given":"Aneta","family":"Gawlik","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Pediatric Endocrinology, Medical University of Silesia, 40-752 Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Koszutski","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Urology, Medical University of Silesia, 40-752 Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,5,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.ecl.2015.02.002","article-title":"Adrenal Steroidogenesis and Congenital Adrenal Hyperplasia","volume":"44","author":"Turcu","year":"2015","journal-title":"Endocrinol. 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