{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T14:52:24Z","timestamp":1773327144628,"version":"3.50.1"},"reference-count":28,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>The aim of the study was to make a comparative studies on the effectiveness of platelet rich plasma (PRP) and hyaluronic acid (HA) in intra-articular injections to the temporomandibular joints\u2014in double blind studies application\u2014based on the analysis of selected clinical parameters of functional efficiency and the mean value of joint\u2019s pain intensity before and after management. The study enrolled a group of 100 patients, aged 21 to 43 years, of both sexes, who came for the prosthodontic treatment. All patients had II b group of disorder according to the Research Diagnostic Criteria\/Temporomandibular Disorder, and were consecutively, alternately assigned to the groups, 50 patients in each. Study group PRP was treated with intra-articular injection of platelet rich plasma and study group HA had injection with hyaluronic acid. The examination was double-blind, so that the injecting physician and the patient were not informed what kind of medicinal substance they received in the joint injection. The final selected clinical parameters did not differ statistically significantly between the groups, what means that both administered substances were effective in the repair of intra-articular structures. The results of research showed that the use of PRP and HA in intraarticular joint\u2019s injections positively affects in selected clinical parameters and decrease of the pain in temporomandibular joints in the case of disc displacement without reduction.<\/jats:p>","DOI":"10.3390\/ijerph17134726","type":"journal-article","created":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T01:54:56Z","timestamp":1593568496000},"page":"4726","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["The Application of Intra-Articulr Injections for Management of the Consequences of Disc Displacement without Reduction"],"prefix":"10.3390","volume":"17","author":[{"given":"Malgorzata","family":"Pihut","sequence":"first","affiliation":[{"name":"Prosthodontics Department, Consulting Room of Temporomandibular Disorders, Jagiellonian University, Medical College, 4 Montelupich Str., 31-155 Krakow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7044-7620","authenticated-orcid":false,"given":"Andrzej","family":"Gala","sequence":"additional","affiliation":[{"name":"Prosthodontics Department, Consulting Room of Temporomandibular Disorders, Jagiellonian University, Medical College, 4 Montelupich Str., 31-155 Krakow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,7,1]]},"reference":[{"key":"ref_1","unstructured":"Okeson, J. 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