{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:08:20Z","timestamp":1785841700774,"version":"3.56.0"},"reference-count":45,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T00:00:00Z","timestamp":1595808000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Background and Objectives: Surveillance of syphilis and gonorrhea in Romania is case-based and makes use of European case definitions. Adolescence is a period characterized by vulnerabilities and opportunities, a period when health decisions, including those related to sexually transmitted infections, may have a lifetime impact. The present study investigates the trends recorded in the incidence of syphilis and gonorrhea in 15\u201319 year-old adolescents in the central and northwestern regions of Romania. Materials and Methods: An observational study was conducted and this included surveillance data for syphilis and gonorrhea in the period 2005\u20132017 (n = 939). The distribution of demographic and epidemiological variables in adolescents with syphilis and gonorrhea was evaluated, as well as the tendency of the incidence of syphilis and gonorrhea in the studied population. Joinpoint regression analysis was used to characterize the incidence trend for syphilis and gonorrhea. Results: Between 2005 and 2017, 773 cases of syphilis and 166 cases of gonorrhea were reported. The incidence of syphilis and gonorrhea decreased. Most cases of syphilis have been found out by active detection. Most cases of gonorrhea have been found out by passive detection. The age distribution in the group diagnosed with syphilis was similar to that in the group diagnosed with gonorrhea. There was a higher frequency of syphilis in females and gonorrhea was more common in males. Syphilis was more common in rural areas. Gonorrhea was more common in urban areas. Conclusions: There was a decreasing tendency in the incidence of syphilis and gonorrhea in adolescents aged 15\u201319 during the studied period.<\/jats:p>","DOI":"10.3390\/ijerph17155385","type":"journal-article","created":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T04:39:50Z","timestamp":1595824790000},"page":"5385","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["A Joinpoint Regression Analysis of Syphilis and Gonorrhea Incidence in 15\u201319-Year Old Adolescents between 2005 and 2017: A Regional Study"],"prefix":"10.3390","volume":"17","author":[{"given":"Anamaria","family":"Molnar","sequence":"first","affiliation":[{"name":"National Institute of Public Health, Regional Center of Public Health Cluj, Louis Pasteur Str., no. 6, 400349 Cluj-Napoca, Romania"},{"name":"Department of Public Health, Iuliu Ha\u0163ieganu University of Medicine and Pharmacy Cluj-Napoca, Avram Iancu Str., no. 31, 400083 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4557-5364","authenticated-orcid":false,"given":"Mihaela","family":"Iancu","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics and Biostatistics, Iuliu Ha\u0163ieganu University of Medicine and Pharmacy Cluj-Napoca, Louis Pasteur Str., no. 6, 400349 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodica","family":"Radu","sequence":"additional","affiliation":[{"name":"National Institute of Public Health, Regional Center of Public Health Cluj, Louis Pasteur Str., no. 6, 400349 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina Maria","family":"Borzan","sequence":"additional","affiliation":[{"name":"Department of Public Health, Iuliu Ha\u0163ieganu University of Medicine and Pharmacy Cluj-Napoca, Avram Iancu Str., no. 31, 400083 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,7,27]]},"reference":[{"key":"ref_1","unstructured":"European Centre for Disease Prevention and Control (2020, January 28). 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