{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T22:11:07Z","timestamp":1791670267819,"version":"4.3.4"},"reference-count":24,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2020,8,18]],"date-time":"2020-08-18T00:00:00Z","timestamp":1597708800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Hidradenitis suppurativa (HS) is a chronic inflammatory disease that impairs patients\u2019 physical and mental health. However, few studies have considered the consequences of HS on cohabitants. The aims of this study were to explore the impact of HS on the quality of life (QOL) of cohabitants and to assess potentially associated factors. A cross-sectional study was conducted and patients with HS and their cohabitants were invited to participate. Validated questionnaires were used to measure QOL, anxiety and depression, type D personality and sexual dysfunction. The clinical variables of patients and the demographic characteristics of cohabitants were also collected. Twenty-seven patients and 27 cohabitants were included for analysis. Patients and cohabitants presented significant QOL impairment. A direct association was found between the Dermatology Life Quality Index (DLQI) and the Familiar Dermatology Life Quality Index (FDLQI). DLQI scores were associated with the presence of negative affectivity, a trait typical of type D personality, as well as with cohabitants\u2019 anxiety. FDLQI scores were associated with cohabitant anxiety and patient depression. Hidradenitis suppurativa damages quality of life in patients and cohabitants. Identifying potential psychological factors could help us to recognize at-risk patients and apply personalized treatments for them and their environment.<\/jats:p>","DOI":"10.3390\/ijerph17166000","type":"journal-article","created":{"date-parts":[[2020,8,18]],"date-time":"2020-08-18T11:15:27Z","timestamp":1597749327000},"page":"6000","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Quality of Life in Cohabitants of Patients with Hidradenitis Suppurativa: A Cross-sectional Study"],"prefix":"10.3390","volume":"17","author":[{"given":"Carmen","family":"Ramos-Alejos-Pita","sequence":"first","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine, University of Granada, 18016 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4186-1435","authenticated-orcid":false,"given":"Salvador","family":"Arias-Santiago","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine, University of Granada, 18016 Granada, Spain"},{"name":"Department of Dermatology, Hospital Universitario Virgen de las Nieves, 18012 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6882-2113","authenticated-orcid":false,"given":"Alejandro","family":"Molina-Leyva","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital Universitario Virgen de las Nieves, 18012 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,8,18]]},"reference":[{"key":"ref_1","first-page":"30224-4","article-title":"Low Prevalence of GSC Gene Mutations in a Large Cohort of Predominantly Caucasian Patients with Hidradenitis suppurativa","volume":"S0022-202X","author":"Duchatelet","year":"2020","journal-title":"J. Investig. Dermatol."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Nguyen, T.V., Damiani, G., Orenstein, L.A.V., Hamzavi, I., and Jemec, G.B. (2020). Hidradenitis suppurativa: An update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life. J. Eur. Acad. Dermatol. Venereol.","DOI":"10.1111\/jdv.16677"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s13555-020-00354-2","article-title":"Review of comorbidities of Hidradenitis Suppurativa: Implications for Daily Clinical Practice","volume":"10","author":"Tzellos","year":"2020","journal-title":"Dermatol. Ther."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Matusiak, \u0141. (2018). Profound consequences of Hidradenitis suppurativa: A review. Br. J. Dermatol.","DOI":"10.1111\/bjd.16603"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1111\/bjd.15226","article-title":"Autoinflammation in Pyoderma gangrenosum and its syndromic form (pyoderma gangrenosum, acne and suppurative hidradenitis)","volume":"176","author":"Marzano","year":"2017","journal-title":"Br. J. Dermatol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e25","DOI":"10.1136\/annrheumdis-2016-210901","article-title":"Autoinflammatory Disease Damage Index (ADDI): A possible newborn also in Hidradenitis suppurativa daily practice","volume":"76","author":"Damiani","year":"2017","journal-title":"Ann. Rheum. Dis."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Kridin, K., Patel, P.M., Jones, V.A., Damiani, G., Amber, K.T., and Cohen, A.D. (2020). Hidradenitis suppurativa is associated with acne keloidalis nuchae: A population-based study. Arch. Dermatol. Res.","DOI":"10.1007\/s00403-020-02105-x"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"391","DOI":"10.4254\/wjh.v11.i4.391","article-title":"Nonalcoholic fatty liver disease prevalence in an Italian cohort of patients with hidradenitis suppurativa: A multi-center retrospective analysis","volume":"11","author":"Damiani","year":"2019","journal-title":"World J. Hepatol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1016\/j.jaad.2015.07.054","article-title":"The psychosocial impact of hidradenitis suppurativa","volume":"73","author":"Gooderham","year":"2015","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1001\/jamadermatol.2019.0759","article-title":"Depression and anxiety in adults with hidradenitis suppurativa: A systematic review and meta-analysis","volume":"155","author":"Machado","year":"2019","journal-title":"JAMA Dermatol."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Cuenca-Barrales, C., Ruiz-Villaverde, R., and Molina-Leyva, A. (2019). Sexual distress in patients with hidradenitis suppurativa: A cross-sectional study. J. Clin. Med., 8.","DOI":"10.3390\/jcm8040532"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/j.1365-2230.1994.tb01167.x","article-title":"Dermatology life quality index (DLQI)\u2014A simple practical measure for routine clinical use","volume":"19","author":"Finlay","year":"1994","journal-title":"Clin. Exp. Dermatol."},{"key":"ref_13","first-page":"997","article-title":"The Dermatology Life Quality Index 1994\u20132007: A comprehensive review of validation data and clinical results","volume":"159","author":"Basra","year":"2008","journal-title":"Br. J. Dermatol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1111\/j.1365-2133.2006.07617.x","article-title":"The Family Dermatology Life Quality Index: Measuring the secondary impact of skin disease","volume":"156","author":"Basra","year":"2007","journal-title":"Br. J. Dermatol."},{"key":"ref_15","unstructured":"(2019, November 12). Family Dermatology Life Quality Index\u2014School of Medicine\u2014Cardiff University. Available online: https:\/\/www.cardiff.ac.uk\/medicine\/resources\/quality-of-life-questionnaires\/family-dermatology-life-quality-index."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"Zigmund","year":"1983","journal-title":"Acta Psychiatrica. Scand."},{"key":"ref_17","first-page":"195","article-title":"Spanish validation of the type D personality scale (DS14)","volume":"26","author":"Alcaraz","year":"2018","journal-title":"Behav. Psychol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/sj.ijir.3900472","article-title":"Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction","volume":"11","author":"Rosen","year":"1999","journal-title":"Int. J. Impot. Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1111\/j.1743-6109.2009.01635.x","article-title":"Development and validation of a 6-item version of the female sexual function index (FSFI) as a diagnostic tool for female sexual dysfunction","volume":"7","author":"Isidori","year":"2010","journal-title":"J. Sex Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1111\/jdv.12966","article-title":"European S1 guideline for the treatment of Hidradenitis suppurativa\/acne inversa","volume":"29","author":"Zouboulis","year":"2015","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1111\/bjd.15748","article-title":"European Hidradenitis Suppurativa Foundation Investigator Group. Development and validation of the International Hidradenitis Suppurativa Severity Score System (IHS4), a novel dynamic scoring system to assess HS severity","volume":"177","author":"Zouboulis","year":"2017","journal-title":"Br. J. Dermatol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"adv00107","DOI":"10.2340\/00015555-3464","article-title":"Body Image Quality of Life in Patients with Hidradenitis Suppurativa Compared with Other Dermatological Disorders","volume":"100","author":"Nielsen","year":"2020","journal-title":"Acta Derm. Venereol."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"W\u0142odarek, K., G\u0142owaczewska, A., Matusiak, \u0141., and Szepietowski, J.C. (2020). Psychosocial burden of Hidradenitis Suppurativa patients\u2019 partners. J. Eur. Acad. Dermatol. Venereol.","DOI":"10.1111\/jdv.16255"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Marasca, C., Napolitano, M., Monfrecola, G., Masar\u00e0, A., Annunziata, M.C., Donnarumma, M., and Fabbrocini, G. (2020). Quality of life in people living with patients suffering from hidradenitis suppurativa. J. Eur. Acad. Dermatol. Venereol.","DOI":"10.1111\/jdv.16319"}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/17\/16\/6000\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T10:02:39Z","timestamp":1760176959000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/17\/16\/6000"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,18]]},"references-count":24,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2020,8]]}},"alternative-id":["ijerph17166000"],"URL":"https:\/\/doi.org\/10.3390\/ijerph17166000","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,18]]}}}