{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:45:19Z","timestamp":1787028319915,"version":"build-2736575974"},"reference-count":37,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T00:00:00Z","timestamp":1603238400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Parkinson\u2019s disease (PD) is a neurodegenerative disease and a multidisciplinary approach to rehabilitation has been suggested as the best clinical practice. However, very few studies have investigated the long-term effects of a multidisciplinary rehabilitation approach, particularly regarding whether this can slow the progression of PD. The purpose was to investigate the short- and long-term effect of a 2-week multidisciplinary rehabilitation regimen on the PD-related decline in health-related quality of life (HRQOL), mobility, and muscle function. Individuals with PD (IPD) participated in a 2-week inpatient multidisciplinary rehabilitation regimen that focused on improving HRQOL, mobility, and muscle function. Data from the primary outcome: HRQOL (Parkinson\u2019s Disease Questionnaire 39, PDQ-39), secondary outcomes: handgrip strength, Timed-up and Go (TUG), Hospital Anxiety and Depression Scale (HADS), and Falls Efficacy Scale-International (FES-I) were compared at pre-visitation, before and after the 2-week regimen, and again at 4 and 10 months follow-up. In total, 224 patients with PD were included. There were short-term improvements in all outcomes. PDQ-39 was maintained at the same level as pre-visitation after 10 months follow-up. A 2-week multidisciplinary rehabilitation regimen improved short-term mobility, muscle function, and HRQOL in individuals with Parkinson\u2019s disease. HRQOL was maintained after 10 months demonstrating long-term effects.<\/jats:p>","DOI":"10.3390\/ijerph17207668","type":"journal-article","created":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T10:14:22Z","timestamp":1603275262000},"page":"7668","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Health-Related Quality of Life and Physical Function in Individuals with Parkinson\u2019s Disease after a Multidisciplinary Rehabilitation Regimen\u2014A Prospective Cohort Feasibility Study"],"prefix":"10.3390","volume":"17","author":[{"given":"Christina","family":"Nielsen","sequence":"first","affiliation":[{"name":"Department of Physical and Occupational Therapy, Bispebjerg Hospital, 2400 Copenhagen, Denmark"},{"name":"Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M, Bispebjerg Hospital and Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, 2400 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1941-2681","authenticated-orcid":false,"given":"Volkert","family":"Siersma","sequence":"additional","affiliation":[{"name":"Research Unit and Department of General Practice, Institute of Public Health, University of Copenhagen, 1014 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Ghaziani","sequence":"additional","affiliation":[{"name":"Department of Physical and Occupational Therapy, Bispebjerg Hospital, 2400 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Beyer","sequence":"additional","affiliation":[{"name":"Department of Physical and Occupational Therapy, Bispebjerg Hospital, 2400 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Peter","family":"Magnusson","sequence":"additional","affiliation":[{"name":"Department of Physical and Occupational Therapy, Bispebjerg Hospital, 2400 Copenhagen, Denmark"},{"name":"Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M, Bispebjerg Hospital and Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, 2400 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1648-5746","authenticated-orcid":false,"given":"Christian","family":"Coupp\u00e9","sequence":"additional","affiliation":[{"name":"Department of Physical and Occupational Therapy, Bispebjerg Hospital, 2400 Copenhagen, Denmark"},{"name":"Institute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery M, Bispebjerg Hospital and Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, 2400 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,10,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1017\/S031716710000319X","article-title":"Etiology of Parkinson\u2019s disease","volume":"30","author":"Huang","year":"2003","journal-title":"Can. 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