{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T10:35:36Z","timestamp":1792751736302,"version":"4.5.0"},"reference-count":20,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T00:00:00Z","timestamp":1605052800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology of Taiwan","doi-asserted-by":"publisher","award":["MOST 108-2314-B-182-037-MY3"],"award-info":[{"award-number":["MOST 108-2314-B-182-037-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPG8J0611, CMRPG8J1151, CMRPG8F1411, CMRPG8F1412"],"award-info":[{"award-number":["CMRPG8J0611, CMRPG8J1151, CMRPG8F1411, CMRPG8F1412"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Introduction: Kawasaki disease (KD) is a childhood illness causing blood vessel inflammation. Children with KD have similar cardiopulmonary function to healthy children, but lower moderate-to-vigorous activity and exercise self-efficacy\u2014possibly harming their cardiopulmonary function in adolescence. The purpose of this study is to investigate the cardiopulmonary function, exercise behaviors, exercise motivations, and self-efficacy of adolescents who once had KD. Methods: adolescents who once had KD and adolescents matched to the KD group in age and sex were enrolled. The cardiopulmonary exercise test was used to assess cardiopulmonary function. Weekly exercise behavior, exercise motivation, and self-efficacy were assessed with questionnaires. Results: this study recruited 50 and 30 participants, respectively, to the KD and control groups. The KD group had a lower ratio of VO2\/kg at the anaerobic threshold and peak to the predicted VO2\/kg at the peak (p = 0.021 and 0.043, respectively). No significant differences were found in questionnaire scores. The correlations of weekly exercise behavior scores with exercise motivation and self-efficacy scores were stronger in the KD group. Conclusions: adolescents with KD history had significantly lower aerobic metabolism capacity and peak exercise load capacity than controls. The correlations of amount of weekly exercise with exercise motivation and self-efficacy were stronger in the KD group.<\/jats:p>","DOI":"10.3390\/ijerph17228352","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T19:08:28Z","timestamp":1605121708000},"page":"8352","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Patients with Kawasaki Disease Have Significantly Low Aerobic Metabolism Capacity and Peak Exercise Load Capacity during Adolescence"],"prefix":"10.3390","volume":"17","author":[{"given":"Tsung-Hsun","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Yuh","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin-Yi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ta-Chih","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling-Sai","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan"},{"name":"Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3295-2984","authenticated-orcid":false,"given":"Ho-Chang","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan"},{"name":"Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,11,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1007\/s00246-015-1186-5","article-title":"Cardiovascular response to exercise testing in children and adolescents late after kawasaki disease according to coronary condition upon onset","volume":"36","author":"Gravel","year":"2015","journal-title":"Pediatr. Cardiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e2444","DOI":"10.1097\/MD.0000000000002444","article-title":"Cardiopulmonary function, exercise capacity, and echocardiography finding of pediatric patients with kawasaki disease: An observational study","volume":"95","author":"Tuan","year":"2016","journal-title":"Medicine"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1177\/0009922812441664","article-title":"Factors associated with low moderate-to-vigorous physical activity levels in pediatric patients with kawasaki disease","volume":"51","author":"Banks","year":"2012","journal-title":"Clin. Pediatr. (Phila.)"},{"key":"ref_4","unstructured":"(2020, May 23). Z Score Calculator by Taiwan Society of Pediatric Cardiology. Available online: http:\/\/www.tspc.org.tw\/service\/z_score.asp."},{"key":"ref_5","first-page":"266","article-title":"Coronary diameters in taiwanese children younger than 6 years old: Z-score regression equations derived from body surface area","volume":"30","author":"Lin","year":"2014","journal-title":"Acta Cardiol. Sin."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1161\/CIR.0b013e31829b5b44","article-title":"Exercise standards for testing and training","volume":"128","author":"Fletcher","year":"2013","journal-title":"Circulation"},{"key":"ref_7","unstructured":"American College of Sports Medicine, Riebe, D., Ehrman, J.K., Liguori, G., and Magal, M. (2018). ACSM\u2019s Guidelines for Exercise Testing and Prescription, Wolters Kluwer."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1161\/CIR.0b013e3181e52e69","article-title":"Clinician\u2019s guide to cardiopulmonary exercise testing in adults: A scientific statement from the american heart association","volume":"122","author":"Balady","year":"2010","journal-title":"Circulation"},{"key":"ref_9","first-page":"219","article-title":"Excercise physiology in health and disease","volume":"112","author":"Wasserman","year":"1975","journal-title":"Am. Rev. Respir. Dis."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Kinnear, W., and Blakey, J. (2014). A practical guide to the interpretation of cardio-pulmonary exercise tests (oxford respiratory medicine library). Oxygen Pulse, Oxford University Press.","DOI":"10.1093\/med\/9780198702467.001.0001"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"S36","DOI":"10.1097\/00005768-199706001-00009","article-title":"Godin leisure-time exercise questionnaire","volume":"29","author":"Godin","year":"1997","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref_12","first-page":"141","article-title":"A simple method to assess exercise behavior in the community","volume":"10","author":"Godin","year":"1985","journal-title":"Can. J. Appl. Sport Sci."},{"key":"ref_13","first-page":"167","article-title":"Reliability and validity of the chinese version of the \u201cbehavior regulation in exercise questionnaire-2\u201d (breq-2)","volume":"37","author":"Chen","year":"2012","journal-title":"Formos J. Phys. Ther."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1123\/jsep.26.2.191","article-title":"A modification to the behavioural regulation in exercise questionnaire to include an assessment of amotivation","volume":"26","author":"Markland","year":"2004","journal-title":"J. Sport Exerc. Psychol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1080\/02701367.2008.10599485","article-title":"Evidence for a multidimensional self-efficacy for exercise scale","volume":"79","author":"Rodgers","year":"2008","journal-title":"Res. Q. Exerc. Sport"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1080\/00401706.1964.10490181","article-title":"Multiple comparisons using rank sums","volume":"6","author":"Dunn","year":"1964","journal-title":"Technometrics"},{"key":"ref_17","unstructured":"Rosner, B. (2015). Fundamentals of Biostatistics, Nelson Education."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1136\/heart.83.3.307","article-title":"Long term consequences of regressed coronary aneurysms after kawasaki disease: Vascular wall morphology and function","volume":"83","author":"Iemura","year":"2000","journal-title":"Heart Br. Card. Soc."},{"key":"ref_19","unstructured":"(2020, September 06). Physical Activity and Adults. Available online: http:\/\/www.who.int\/dietphysicalactivity\/factsheet_adults\/en\/."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S2352-4642(19)30323-2","article-title":"Global trends in insufficient physical activity among adolescents: A pooled analysis of 298 population-based surveys with 1\u00b76 million participants","volume":"4","author":"Guthold","year":"2020","journal-title":"Lancet Child Adolesc. 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