{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:16:09Z","timestamp":1788520569819,"version":"build-2803163510"},"reference-count":40,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2020,12,3]],"date-time":"2020-12-03T00:00:00Z","timestamp":1606953600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007771","name":"\u015al\u0105ski Uniwersytet Medyczny","doi-asserted-by":"publisher","award":["KNW-1-154\/K\/9\/0"],"award-info":[{"award-number":["KNW-1-154\/K\/9\/0"]}],"id":[{"id":"10.13039\/100007771","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>During physical exercise, the absorbed dose of air pollutants increases. Acute effects of exposure to air pollutants during exercise in healthy young adults remain poorly documented. The aim of this study was to assess the acute responses in fractionated exhaled nitric oxide (FeNO) and blood pressure to air pollution exposure during exercise in young adults with different physical activity levels (low or high). In this study, 76 healthy university students participating in physical activity classes (low level of physical activity) and attending sports training (high level of physical activity) completed two indoor exercise trials when air pollutant concentrations were high (exposure trial) and when the quality of the air was good (control trial). We monitored indoor particulate matter with diameter &lt;10 \u00b5m and &lt;2.5 \u00b5m (PM10 and PM2.5) and outdoor PM10, nitric oxides (NO2, NOx, NO), and sulfur dioxide (SO2) concentrations. Systolic and diastolic blood pressure (SBP and DBP), heart rate (HR), oxygen saturation (SpO2), and FeNO were measured at baseline and after 45\u201360 min of physical activity. There were no significant differences between physiological responses to training performed under different exposure conditions in blood pressure, HR, and SpO2. Significant positive correlations between post-exercise \u0394FeNO during exposure trials and ambient air pollutants were found. FeNO increase during the exposure trial was associated with a higher physical activity level and higher outdoor PM10 and NO2 concentrations. In young and healthy adults, some differences in physiological responses to physical activity between polluted and control environments could be observed. Participants with a high physical activity level were more likely to have an increase in FeNO after exercise in a polluted environment but not after the control exercise trials.<\/jats:p>","DOI":"10.3390\/ijerph17239012","type":"journal-article","created":{"date-parts":[[2020,12,3]],"date-time":"2020-12-03T11:15:43Z","timestamp":1606994143000},"page":"9012","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Acute FeNO and Blood Pressure Responses to Air Pollution Exposure in Young Adults during Physical Activity"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2279-5409","authenticated-orcid":false,"given":"Krzysztof","family":"Kocot","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, 40-752 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0106-9662","authenticated-orcid":false,"given":"Kamil","family":"Bara\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, 40-752 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edyta","family":"Melaniuk-Wolny","sequence":"additional","affiliation":[{"name":"Department of Air Protection, Faculty of Energy and Environmental Engineering, Silesian University of Technology in Gliwice, 44-100 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8817-2058","authenticated-orcid":false,"given":"Elwira","family":"Zajusz-Zubek","sequence":"additional","affiliation":[{"name":"Department of Air Protection, Faculty of Energy and Environmental Engineering, Silesian University of Technology in Gliwice, 44-100 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9386-0346","authenticated-orcid":false,"given":"Ma\u0142gorzata","family":"Kowalska","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, 40-752 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,12,3]]},"reference":[{"key":"ref_1","first-page":"919","article-title":"Diet and Physical Activity for Cardiovascular Disease Prevention","volume":"93","author":"Lanier","year":"2016","journal-title":"Am. Family Phys."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1097\/HCR.0000000000000139","article-title":"Air Pollution and Exercise A Rewiev of the Cardiovascular Implications for Health Care Professionals","volume":"36","author":"Giorgini","year":"2016","journal-title":"J. Cardiopulm. Rehabil. Prev."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Wahid, A., Manek, N., Nichols, M., Kelly, P., Foster, C., Webster, P., Kaur, A., Friedmann Smith, C., Wilkins, E., and Rayner, M. (2016). Quantifying the Association Between Physical Activity and Cardiovascular Disease and Diabetes: A Systematic Review and Meta-Analysis. J. Am. Heart Assoc., 5.","DOI":"10.1161\/JAHA.115.002495"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/sms.12581","article-title":"Exercise as medicine-Evidence for prescribing exercise as therapy in 26 different chronic diseases","volume":"25","author":"Pedersen","year":"2015","journal-title":"Scand. J. Med. Sci. Sport"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"4511","DOI":"10.1016\/j.scitotenv.2011.07.020","article-title":"Effects of physical activity on the deposition of traffic-related particles into the human lungs in silico","volume":"409","author":"Ruuskanen","year":"2011","journal-title":"Sci. Total Environ."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s40279-013-0108-z","article-title":"The Health Effects of Exercising in Air Pollution","volume":"44","author":"Giles","year":"2014","journal-title":"Sport Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1600419","DOI":"10.1183\/13993003.00419-2016","article-title":"A joint ERS\/ATS policy statement: What constitutes an adverse health effect of air pollution? An analytical framework","volume":"49","author":"Thurston","year":"2017","journal-title":"Eur. Respir. J."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.envint.2014.10.005","article-title":"A review on the human health impact of airborne particulate matter","volume":"74","author":"Kim","year":"2015","journal-title":"Environ. Int."},{"key":"ref_9","unstructured":"Badilla, G.L., Valdez, B., and Schorr, M. (2012). Short-Term Effect of Changes in Fine Particulate Matter Concentrations in Ambient Air to Daily Cardio-Respiratory Mortality in Inhabitants of Urban-Industrial Agglomeration (Katowice Agglomeration), Poland. Air Quality-New Perspective, IntechOpen."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0140-6736(17)32643-0","article-title":"Respiratory and cardiovascular responses to walking down a traffic-polluted road compared with walking in a traffic-free area in participants aged 60 years and older with chronic lung or heart disease and age-matched healthy controls: A randomised, crossover study","volume":"10118","author":"Sinharay","year":"2018","journal-title":"Lancet"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"106195","DOI":"10.1016\/j.ypmed.2020.106195","article-title":"Acute effects of short-term exposure to air pollution while being physically active, the potential for modification: A review of the literature","volume":"139","author":"Lobdell","year":"2020","journal-title":"Prev. Med."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"108647","DOI":"10.1016\/j.envres.2019.108647","article-title":"Cardio-respiratory health effects of exposure to traffic-related air pollutants while exercising outdoors: A systematic review","volume":"178","author":"Madureira","year":"2019","journal-title":"Environ. Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1177\/2047487314555602","article-title":"Arterial blood pressure responses to short-term exposure to low and high traffic-related air pollution with and without moderate physical activity","volume":"22","author":"Kubesch","year":"2015","journal-title":"Eur. J. Prev. Cardiol."},{"key":"ref_14","unstructured":"Elliott, L., and Loomis, D. (2020). Respiratory effects of road pollution in recreational cyclists: A pilot study. Arch. Environ. Occup. Health, 1\u20139."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.envint.2016.10.011","article-title":"Acute respiratory response to traffic-related air pollution during physical activity performance","volume":"97","author":"Matt","year":"2016","journal-title":"Environ. Int."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1136\/oemed-2014-102106","article-title":"Respiratory and inflammatory responses to short-term exposure to traffic-related air pollution with and without moderate physical activity","volume":"72","author":"Kubesch","year":"2015","journal-title":"Occup. Environ. Medm"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"28","DOI":"10.2174\/1381612822666151109111712","article-title":"Air Pollution Exposure and Blood Pressure: An Updated Review of the Literature","volume":"22","author":"Giorgini","year":"2016","journal-title":"Currm. Pharmm. Desm."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1097\/HJH.0000000000000342","article-title":"Effect of exposure to PM2.5 on blood pressure: A systematic review and meta-analysis","volume":"32","author":"Liang","year":"2014","journal-title":"J. Hypertens."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.iac.2018.06.001","article-title":"Exhaled Nitric Oxide An Update","volume":"38","author":"Hoyte","year":"2018","journal-title":"Immunol. Allergy Clin. N. Am."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.envres.2016.06.022","article-title":"Association between fine particulate matter chemical constituents and airway inflammation: A panel study among healthy adults in China","volume":"150","author":"Shi","year":"2016","journal-title":"Environ. Res."},{"key":"ref_21","first-page":"5","article-title":"Cardiorespiratory biomarker responses in healthy young adults to drastic air quality changes surrounding the 2008 Beijing Olympics","volume":"174","author":"Zhang","year":"2013","journal-title":"Res. Rep. Health Eff. Inst."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Prossegger, J., Huber, D., Grafetstatter, C., Pchler, C., Braunschmid, H., Weisbock-Erdheim, R., and Hartl, A. (2019). Winter exercise reduces allergic airway inflammation: A randomized controlled study. Int. J. Environ. Res. Public Health, 16.","DOI":"10.3390\/ijerph16112040"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1249\/MSS.0000000000001632","article-title":"Black Carbon Reduces the Beneficial Effect of Physical Activity on Lung Function","volume":"50","author":"Laeremans","year":"2018","journal-title":"Med. Sci. Sport Exerc."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.wem.2019.10.005","article-title":"Exercise in Thermal Inversions: PM2.5 Air Pollution Effects on Pulmonary Function and Aerobic Performance","volume":"31","author":"Wagner","year":"2020","journal-title":"Wilderness Environ. Med."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jesf.2018.01.002","article-title":"Effects of ambient particulate matter on aerobic exercise performance","volume":"16","author":"Wagner","year":"2018","journal-title":"J. Exerc. Sci. Fit."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.ypmed.2016.02.002","article-title":"Can air pollution negate the health benefits of cycling and walking?","volume":"87","author":"Tainio","year":"2016","journal-title":"Prev. Med."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"349","DOI":"10.32394\/pe.73.22","article-title":"Recreational physical activity and the problem of particulate matter air pollution","volume":"73","author":"Kocot","year":"2019","journal-title":"Przegl. Epidemiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s10661-018-6797-x","article-title":"Characteristics of air quality and sources affecting high levels of PM10 and PM2.5 in Poland, Upper Silesia urban area","volume":"190","author":"Kobza","year":"2018","journal-title":"Environ. Monit. Assess"},{"key":"ref_29","unstructured":"Wojew\u00f3dzki Inspektorat Ochrony \u015arodowiska w Katowicach (2019). Ocena Stanu \u015arodowiska w Wojew\u00f3dztwie \u015al\u0105skim w 2018 Roku, Wojew\u00f3dzki Inspektorat Ochrony \u015arodowiska w Katowicach. (In Polish)."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"143","DOI":"10.7163\/GPol.0115","article-title":"Physico-geographical mesoregions of poland: Verification and adjustment of boundaries on the basis of contemporary spatial data","volume":"91","author":"Solon","year":"2018","journal-title":"Geogr. Pol."},{"key":"ref_31","unstructured":"Institute of Meteorology and Water Management\u2013Natiolnal Research Institute (2019). Climate Monitoring Bulletin of Poland Year 2019, Institute of Meteorology and Water Management."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1080\/07420528.2017.1325896","article-title":"The effect of air pollution on diurnal variation of performance in anaerobic tests, cardiovascular and hematological parameters, and blood gases on soccer players following the Yo-Yo Intermittent Recovery Test Level-1","volume":"34","author":"Boussetta","year":"2017","journal-title":"Chronobiol. Int."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/s12989-014-0070-4","article-title":"Exposure to traffic-related air pollution during physical activity and acute changes in blood pressure, autonomic and micro-vascular function in women: A cross-over study","volume":"11","author":"Weichenthal","year":"2014","journal-title":"Part Fibre Toxicol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/jes.2015.66","article-title":"Impact of traffic-related air pollution on acute changes in cardiac autonomic modulation during rest and physical activity: A cross-over study","volume":"26","author":"Weichenthal","year":"2016","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"73","DOI":"10.3389\/fcell.2014.00073","article-title":"Exercise and NO production: Relevance and implications in the cardiopulmonary system","volume":"2","author":"Nosarev","year":"2015","journal-title":"Front. Cell Dev. Biol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"11859","DOI":"10.1021\/acs.est.5b02527","article-title":"Fine Particulate Matter Constituents, Nitric Oxide Synthase DNA Methylation and Exhaled Nitric Oxide","volume":"49","author":"Chen","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1289\/ehp.1104389","article-title":"Respiratory health effects of airborne particulate matter: The role of particle size, composition, and oxidative potential-the RAPTES project","volume":"120","author":"Strak","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"649","DOI":"10.13075\/ijomeh.1896.01533","article-title":"The effect of upper respiratory allergy on acute respiratory response to ambient air pollution during physical exercise","volume":"33","author":"Kocot","year":"2020","journal-title":"Int. J. Occup. Med. Environ Health"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1249\/MSS.0b013e31824b2877","article-title":"Anti-inflammatory effects of aerobic exercise in mice exposed to air pollution","volume":"44","author":"Toledo","year":"2012","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"4868536","DOI":"10.1155\/2016\/4868536","article-title":"Update on the Mechanisms of Pulmonary Inflammation and Oxidative Imbalance Induced by Exercise","volume":"2016","author":"Araneda","year":"2016","journal-title":"Oxid. Med. Cell Longev."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/17\/23\/9012\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T10:41:06Z","timestamp":1760179266000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/17\/23\/9012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,3]]},"references-count":40,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2020,12]]}},"alternative-id":["ijerph17239012"],"URL":"https:\/\/doi.org\/10.3390\/ijerph17239012","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,3]]}}}