{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:32:24Z","timestamp":1788222744560,"version":"build-2803163510"},"reference-count":13,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T00:00:00Z","timestamp":1613433600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 106-2314-B-277-003-MY2"],"award-info":[{"award-number":["MOST 106-2314-B-277-003-MY2"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Diabetic foot ulcer (DFU) is one of the common complications of diabetes. DFU can cause a huge medical and financial burden due to infections, compromise the quality of life, and increase the mortality rate in patients. However, the consumption of medical resources for DFU is rarely mentioned. A retrospective cohort study was performed. Data were obtained from the National Health Insurance Research Database of Taiwan, and the prevalence and medical utilization data for DFU in 2001\u20132015 were extracted, followed by the analysis for high-risk populations. Between 2001 and 2015, there were 7511 new DFU patients. A higher proportion in these patients was male, elderly with a low education level, and low income. Between 2001 and 2015, the prevalence of DFU was 0.5\u20130.8%, and the number of DFU patients showed stable growth. Every year, 12.6\u201319.3% and 1.2\u20137.0% of patients underwent debridement and amputation, respectively. The hospitalization fees increased year on year. Our study showed that the DFU prevalence increased year on year, and the DFU medical expenditure increased. DFU tends to occur in males, patients with low socioeconomic status, low education level, those with multiple comorbidities, and old age. Therefore, DFU care and prevention require the entire healthcare system to jointly formulate a prevention plan.<\/jats:p>","DOI":"10.3390\/ijerph18041891","type":"journal-article","created":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T05:02:14Z","timestamp":1613451734000},"page":"1891","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Prevalence and Medical Resource of Patients with Diabetic Foot Ulcer: A Nationwide Population-Based Retrospective Cohort Study for 2001\u20132015 in Taiwan"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4225-6990","authenticated-orcid":false,"given":"Chia-Hui","family":"Tai","sequence":"first","affiliation":[{"name":"Department of Nursing, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan"},{"name":"Institute of Medical Sciences, Tzu Chi University, Hualien 970374, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsung-Cheng","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Institute of Medical Sciences, Tzu Chi University, Hualien 970374, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6624-5893","authenticated-orcid":false,"given":"Ru-Ping","family":"Lee","sequence":"additional","affiliation":[{"name":"Institute of Medical Sciences, Tzu Chi University, Hualien 970374, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Fen","family":"Lo","sequence":"additional","affiliation":[{"name":"Institute of Medical Sciences, Tzu Chi University, Hualien 970374, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,2,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"American Diabetes Association (2018). 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PLoS ONE, 15.","DOI":"10.1371\/journal.pone.0239236"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"651","DOI":"10.2337\/dc13-2176","article-title":"Burden of diabetic foot ulcers for medicare and private insurers","volume":"37","author":"Rice","year":"2014","journal-title":"Diabetes Care"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1111\/dme.13973","article-title":"The cost of diabetic foot ulcers and amputations to the National Health Service in England","volume":"36","author":"Kerr","year":"2019","journal-title":"Diabet. Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1080\/17571472.2010.11493315","article-title":"An overview of the healthcare system in Taiwan","volume":"3","author":"Wu","year":"2010","journal-title":"Lond. J. Prim. Care"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e000795","DOI":"10.1136\/bmjdrc-2019-000795","article-title":"Nationwide trends in the epidemiology of diabetic foot complications and lower-extremity amputation over an 8-year period","volume":"7","author":"Lin","year":"2019","journal-title":"BMJ Open Diabetes Res. Care"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"S309","DOI":"10.1016\/S0168-8227(14)70735-1","article-title":"Team care of type 2 diabetes mellitus in Taiwan","volume":"106","author":"Wang","year":"2014","journal-title":"Diabetes Res. Clin. Pr."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/18\/4\/1891\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:24:41Z","timestamp":1760160281000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/18\/4\/1891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,16]]},"references-count":13,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,2]]}},"alternative-id":["ijerph18041891"],"URL":"https:\/\/doi.org\/10.3390\/ijerph18041891","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,16]]}}}