{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:05:34Z","timestamp":1790723134309,"version":"4.1.0"},"reference-count":56,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,2,21]],"date-time":"2021-02-21T00:00:00Z","timestamp":1613865600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>(1) Background: Chronic non-cancer pain (CNCP) remains a public health challenge around the world. Opioids (PO) have been increasingly used in the treatment of CNCP in the last 20 years. This study aimed to assess the prevalence of opioid misuse and prescribed-opioid use disorder (p-OUD) among patients with CNCP in a pain centre in France, and to analyse risk factors for moderate or severe p-OUD. (2) Method: A cross-sectional study was conducted, including patients consulting for pain management in the pain centre of Brest University Hospital. A self-questionnaire was administered (sociodemographic data, medical data, PO misuse, and p-OUD according the Diagnostic and Statistical Manual of Mental Disorders 5 (DSM 5) criteria). Descriptive, univariate, and multivariate analyses were conducted, together with a principal component analysis, in order to identify factors associated with p-OUD. (3) Results: In total, 115 patients were included, the majority of whom were women, with a mean age of 52 years old [18\u201382]; 64.3% (n = 74) had a current prescription for opioid analgesics (weak or strong). In this group, 56.7% (n = 42) had no or only mild p-OUD and 43.3% (n = 32) had current moderate or severe p-OUD. Patients with moderate or severe p-OUD were more likely to have a current antidepressant prescription, to have had psychotherapy, to currently use strong opioids and oxycodone, and to report taking more frequent doses than prescribed and feeling dependent. (4) Conclusions: We showed that the prevalence of current moderate\/severe p-OUD concerned 43.3% of the patients with a CNCP seeking treatment in a pain centre. According to these results, several measures are relevant in managing p-OUD among patients with CNCP.<\/jats:p>","DOI":"10.3390\/ijerph18042097","type":"journal-article","created":{"date-parts":[[2021,2,21]],"date-time":"2021-02-21T22:04:15Z","timestamp":1613945055000},"page":"2097","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Analgesic Opioid Misuse and Opioid Use Disorder among Patients with Chronic Non-Cancer Pain and Prescribed Opioids in a Pain Centre in France"],"prefix":"10.3390","volume":"18","author":[{"given":"Morgane","family":"Guillou-Landreat","sequence":"first","affiliation":[{"name":"INSERM UMR 1246, SPHERE, Methods in Patient-Centered Outcomes and Health Research, Nantes and Tours Universities, 44000 Nantes, France"},{"name":"EA 7479 SPURBO, BREST University, 29200 Brest, France"},{"name":"HUGOPSY Network, 35000 Rennes, France"},{"name":"CHRU, Hopital de la Cavale Blanche, 29200 Brest, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Quinio","sequence":"additional","affiliation":[{"name":"CHRU, Hopital de la Cavale Blanche, 29200 Brest, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Yves","family":"Le Reste","sequence":"additional","affiliation":[{"name":"EA 7479 SPURBO, BREST University, 29200 Brest, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Le Goff","sequence":"additional","affiliation":[{"name":"EA 7479 SPURBO, BREST University, 29200 Brest, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Fonsecca","sequence":"additional","affiliation":[{"name":"EA 7479 SPURBO, BREST University, 29200 Brest, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0722-7243","authenticated-orcid":false,"given":"Marie","family":"Grall-Bronnec","sequence":"additional","affiliation":[{"name":"INSERM UMR 1246, SPHERE, Methods in Patient-Centered Outcomes and Health Research, Nantes and Tours Universities, 44000 Nantes, France"},{"name":"EA 7479 SPURBO, BREST University, 29200 Brest, France"},{"name":"HUGOPSY Network, 35000 Rennes, France"},{"name":"CHU Nantes, Addictology and Psychiatry Department, 44000 Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5101-9738","authenticated-orcid":false,"given":"Antoine","family":"Dany","sequence":"additional","affiliation":[{"name":"EA 7479 SPURBO, BREST University, 29200 Brest, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,2,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2770","DOI":"10.1111\/bph.13873","article-title":"The dynamic interaction between pain and opioid misuse","volume":"175","author":"Moron","year":"2018","journal-title":"Br. 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