{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T02:39:11Z","timestamp":1789267151615,"version":"build-2803163510"},"reference-count":50,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T00:00:00Z","timestamp":1615161600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Estonian Ministry of Education and Research","award":["IUT34-16"],"award-info":[{"award-number":["IUT34-16"]}]},{"DOI":"10.13039\/501100006598","name":"Enterprise Estonia","doi-asserted-by":"publisher","award":["EU48695"],"award-info":[{"award-number":["EU48695"]}],"id":[{"id":"10.13039\/501100006598","id-type":"DOI","asserted-by":"publisher"}]},{"name":"European Commission Horizon 2020","award":["692065 (project WIDENLIFE)"],"award-info":[{"award-number":["692065 (project WIDENLIFE)"]}]},{"name":"MSCA-RISE-2015 project MOMENDO","award":["691058"],"award-info":[{"award-number":["691058"]}]},{"name":"Spanish Ministry of Economy, Industry and Competitiveness (MINECO) and European Regional Development Fund (FEDER)","award":["RYC-2016-21199"],"award-info":[{"award-number":["RYC-2016-21199"]}]},{"name":"Spanish Ministry of Economy, Industry and Competitiveness (MINECO) and European Regional Development Fund (FEDER)","award":["ENDORE SAF2017- 87526-R"],"award-info":[{"award-number":["ENDORE SAF2017- 87526-R"]}]},{"name":"FEDER\/Junta de Andaluc\u00eda-Consejer\u00eda de Econom\u00eda y Conocimiento: MENDO","award":["B-CTS-500-UGR18"],"award-info":[{"award-number":["B-CTS-500-UGR18"]}]},{"name":"European Regional Development Funds","award":["SOMM17\/6107\/UGR"],"award-info":[{"award-number":["SOMM17\/6107\/UGR"]}]},{"name":"Karolinska Institutet Foundation grants","award":["2011FoBi1184"],"award-info":[{"award-number":["2011FoBi1184"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Background: The aim of this study was to investigate the association of physical activity (PA) with assisted reproductive technology (ART) treatment and pregnancy outcomes among couples seeking infertility treatment. Methods: This prospective cohort study was carried out among 128 infertile individuals (64 couples), entering the infertility clinic for ART procedures. Baseline PA (before entering any treatment) was assessed using accelerometry for both women and men. For every couple the infertility treatment outcomes were recorded. Results: The couples that required invasive ART procedures such as in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) spent less time in vigorous PA (\u221273 min\/week per couple, woman + man) than those couples who became spontaneously pregnant after entering the study (p = 0.001). We observed no significant associations between the time spent in physical activities and positive pregnancy test or live birth. Conclusions: Our results do not support a positive nor negative relation between the time the couples spent in physical activities and the chances of getting pregnant or having a baby among patients seeking infertility treatment. However, couples undergoing invasive ART procedures did less vigorous PA than couples that became spontaneously pregnant, suggesting that PA may interfere with their reproductive health.<\/jats:p>","DOI":"10.3390\/ijerph18052718","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T12:12:18Z","timestamp":1615205538000},"page":"2718","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7325-6523","authenticated-orcid":false,"given":"Siret","family":"L\u00e4\u00e4nelaid","sequence":"first","affiliation":[{"name":"Institute of Family Medicine and Public Health, University of Tartu, Ravila 19, 50411 Tartu, Estonia"},{"name":"Department of Nursing and Midwifery, Tartu Health Care College, Nooruse 5, 50411 Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2001-1121","authenticated-orcid":false,"given":"Francisco B.","family":"Ortega","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sports, University of Granada, Carretera de Alfacar, S\/N CP, 18071 Granada, Spain"},{"name":"Department of Biosciences and Nutrition, Karolinska Institutet, NEO, SE-14183 Huddinge, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2112-8674","authenticated-orcid":false,"given":"Theodora","family":"Kunovac Kallak","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health, Uppsala University, SE-751 85 Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lana","family":"Joelsson","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health, Uppsala University, SE-751 85 Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7548-7138","authenticated-orcid":false,"given":"Jonatan R.","family":"Ruiz","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sports, University of Granada, Carretera de Alfacar, S\/N CP, 18071 Granada, Spain"},{"name":"Department of Biosciences and Nutrition, Karolinska Institutet, NEO, SE-14183 Huddinge, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julius","family":"Hreinsson","sequence":"additional","affiliation":[{"name":"Minerva Fertility Clinic, K\u00e5ls\u00e4ngsgr\u00e4nd 10 d, 753 19 Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8818-4531","authenticated-orcid":false,"given":"Kjell","family":"W\u00e5nggren","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health, Uppsala University, SE-751 85 Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anneli","family":"Stavreus-Evers","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health, Uppsala University, SE-751 85 Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Kalda","sequence":"additional","affiliation":[{"name":"Institute of Family Medicine and Public Health, University of Tartu, Ravila 19, 50411 Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1251-8160","authenticated-orcid":false,"given":"Andres","family":"Salumets","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Institute of Clinical Medicine, University of Tartu, L. Puusepa 8, 50406 Tartu, Estonia"},{"name":"Competence Centre on Health Technologies, Teaduspargi 13, 50411 Tartu, Estonia"},{"name":"Institute of Genomics, University of Tartu, Riia 23b, 51010 Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0708-1865","authenticated-orcid":false,"given":"Signe","family":"Altm\u00e4e","sequence":"additional","affiliation":[{"name":"Competence Centre on Health Technologies, Teaduspargi 13, 50411 Tartu, Estonia"},{"name":"Department of Biochemistry and Molecular Biology, Faculty of Sciences, University of Granada, Avenida de la Fuente Nueva S\/N, 18071 Granada, Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria ibs.GRANADA, Parque Tecnol\u00f3gico de la Salud, 18016 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.clinbiochem.2018.03.012","article-title":"Fertility and infertility: Definition and epidemiology","volume":"62","author":"Vander","year":"2018","journal-title":"Clin. 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