{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T13:40:00Z","timestamp":1773150000567,"version":"3.50.1"},"reference-count":58,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T00:00:00Z","timestamp":1615248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Incidence of sexually transmitted infections (STIs) such as chlamydia, gonorrhea, and syphilis has increased in recent years in the US and in European countries. In order to implement effective educational programs, the interests of target populations have to be identified. Since the internet is an important source of information-gathering on health issues, this study investigates web search data in large German cities related to STIs. Google Ads Keyword Planner was used to identify STI-related terms and their search volume in eleven German cities from June 2015 to May 2019. The data obtained were analyzed descriptively with regard to total search volumes, search volumes of specific thematic areas, and search volumes per 100,000 inhabitants. Overall, 741 terms with a total search volume of 5,142,560 queries were identified, with more than 70% of all search queries including a specific disease and \u201cchlamydia\u201d being the overall most often searched term (n = 1,196,160). Time courses of search behavior displayed a continuous interest in STIs with synchronal and national rather than regional peaks. Volumes of search queries lacked periodic patterns. Based on the findings of this study, a more open public discussion about STIs with linkage to increased media coverage and clarification of responsibilities among all STI-treating disciplines concerning management of STIs seem advisable.<\/jats:p>","DOI":"10.3390\/ijerph18052771","type":"journal-article","created":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T12:08:01Z","timestamp":1615291681000},"page":"2771","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Interest in Sexually Transmitted Infections: Analysis of Web Search Data Terms in Eleven Large German Cities from 2015 to 2019"],"prefix":"10.3390","volume":"18","author":[{"given":"Anna Caroline","family":"Pilz","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy, School of Medicine, Technical University of Munich, 80802 Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2749-9791","authenticated-orcid":false,"given":"Linda","family":"Tizek","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, School of Medicine, Technical University of Munich, 80802 Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melvin","family":"R\u00fcth","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, School of Medicine, Technical University of Munich, 80802 Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6332-3323","authenticated-orcid":false,"given":"Peter","family":"Seiringer","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, School of Medicine, Technical University of Munich, 80802 Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tilo","family":"Biedermann","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, School of Medicine, Technical University of Munich, 80802 Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9313-6588","authenticated-orcid":false,"given":"Alexander","family":"Zink","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy, School of Medicine, Technical University of Munich, 80802 Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"548","DOI":"10.2471\/BLT.18.228486","article-title":"Chlamydia, gonorrhoea, trichomoniasis and syphilis: Global prevalence and incidence estimates, 2016","volume":"97","author":"Rowley","year":"2019","journal-title":"Bull. World Health Organ."},{"key":"ref_2","unstructured":"World Health Organization (2018). Report on Global Sexually Transmitted Infection Surveillance, 2018, World Health Organization. Available online: https:\/\/www.who.int\/reproductivehealth\/publications\/stis-surveillance-2018\/en\/."},{"key":"ref_3","unstructured":"U.S. Department of Health and Human Services, and Centers for Disease Control and Prevention (2020, November 07). Sexually Transmitted Disease Surveillance 2018, Available online: https:\/\/www.cdc.gov\/std\/stats18\/natoverview.htm."},{"key":"ref_4","unstructured":"European Centre for Disease Prevention and Control (ECDC) (2020). Syphilis\u2014Annual Epidemiological Report for 2018, European Centre for Disease Prevention and Control (ECDC). Available online: https:\/\/www.ecdc.europa.eu\/en\/publications-data\/syphilis-annual-epidemiological-report-2018."},{"key":"ref_5","unstructured":"European Centre for Disease Prevention and Control (ECDC) (2020). Gonorrhoea\u2014Annual Epidemiological Report for 2018, European Centre for Disease Prevention and Control (ECDC). Available online: https:\/\/www.ecdc.europa.eu\/en\/publications-data\/gonorrhoea-annual-epidemiological-report-2018."},{"key":"ref_6","unstructured":"Robert Koch Institut (2020, November 07). Epidermiologisches Bulletin, Sch\u00e4tzung der Zahl der HIV-Neuinfektionen und der Gesamtzahl von Menschen, die mit HIV in Deutschland leben Stand Ende 2018. Available online: https:\/\/www.rki.de\/DE\/Content\/Infekt\/EpidBull\/Archiv\/2019\/Ausgaben\/46_19.pdf?__blob=publicationFile."},{"key":"ref_7","first-page":"287","article-title":"Bacterial sexually transmitted infections","volume":"17","author":"Buder","year":"2019","journal-title":"J. Dtsch. Dermatol. Ges."},{"key":"ref_8","unstructured":"Government Digital Service (2020, November 07). Public Health England. Guidance. Health Matters: Preventing STIs, Available online: https:\/\/www.gov.uk\/government\/publications\/health-matters-preventing-stis\/health-matters-preventing-stis."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1136\/bmj.322.7295.1135","article-title":"Sexually transmitted infections: Control strategies","volume":"322","author":"Catchpole","year":"2001","journal-title":"BMJ"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Von Rosen, F.T., Von Rosen, A.J., M\u00fcller-Riemenschneider, F., Damberg, I., and Tinnemann, P. (2018). STI Knowledge in Berlin Adolescents. Int. J. Environ. Res. Public Health, 15.","DOI":"10.3390\/ijerph15010110"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.eclinm.2018.08.001","article-title":"STI Risk Perception in the British Population and How It Relates to Sexual Behaviour and STI Healthcare Use: Findings from a Cross-sectional Survey (Natsal-3)","volume":"2\u20133","author":"Clifton","year":"2018","journal-title":"EClinicalMedicine"},{"key":"ref_12","first-page":"548","article-title":"Sexually transmitted diseases: The impact of stigma and taboo on current medical care","volume":"53","year":"2014","journal-title":"Urologe A"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2478\/nor-2013-0052","article-title":"Talking suicide: Online conversations about a taboo subject","volume":"34","author":"Westerlund","year":"2013","journal-title":"Nordicom Rev."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/00224490801987481","article-title":"Sex in America online: An exploration of sex, marital status, and sexual identity in internet sex seeking and its impacts","volume":"45","author":"Albright","year":"2008","journal-title":"J. Sex Res."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0306-4573(99)00056-4","article-title":"Real Users and Real Needs: A Study and Analysis of User Queries on the Web","volume":"36","author":"Jansen","year":"2000","journal-title":"Inf. Process. Manag."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1089\/109493104322820138","article-title":"Sexual information seeking on web search engines","volume":"7","author":"Spink","year":"2004","journal-title":"Cyberpsychol. Behav."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/07448480903221236","article-title":"An Observational Study of How Young People Search for Online Sexual Health Information","volume":"58","author":"Buhi","year":"2009","journal-title":"J. Am. Coll. Health"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1177\/109019819402200308","article-title":"Evaluation of Health Education Programs: Current Assessment and Future Directions","volume":"22","author":"Israel","year":"1995","journal-title":"Health Educ. Q."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1177\/1090198102251021","article-title":"Achieving cultural appropriateness in health promotion programs: Targeted and tailored approaches","volume":"30","author":"Kreuter","year":"2003","journal-title":"Health Educ. Behav."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"S69","DOI":"10.1111\/j.1752-7325.2011.00241.x","article-title":"Qualitative methods to ensure acceptability of behavioral and social interventions to the target population","volume":"71","author":"Ayala","year":"2011","journal-title":"J. Public Health Dent."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1089\/apc.2018.0126","article-title":"Limited Knowledge and Mixed Interest in Pre-Exposure Prophylaxis for HIV Prevention Among People Who Inject Drugs","volume":"32","author":"Bazzi","year":"2018","journal-title":"AIDS Patient Care STDS"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"e127","DOI":"10.2196\/jmir.2116","article-title":"What Young People Want from a Sexual Health Website: Design and Development of Sexunzipped","volume":"14","author":"McCarthy","year":"2012","journal-title":"J. Med. Internet Res."},{"key":"ref_23","unstructured":"Statistisches Bundesamt (2020, November 07). Income, Consumption and Living Conditions. Internet Use by Individuals and Age Groups in %. Available online: https:\/\/www.destatis.de\/EN\/Themes\/Society-Environment\/Income-Consumption-Living-Conditions\/_graphics\/_Interactive\/it-use-age.html."},{"key":"ref_24","unstructured":"Statistica (2020, November 07). Market Share of the Leading Search Engines in Germany in 2018. Available online: https:\/\/www.statista.com\/statistics\/445002\/market-shares-leading-search-engines-germany\/."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"e20588","DOI":"10.2196\/20588","article-title":"Nowcasting Sexually Transmitted Infections in Chicago: Predictive Modeling and Evaluation Study Using Google Trends","volume":"6","author":"Johnson","year":"2020","journal-title":"JMIR Public Health Surveill."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"e018335","DOI":"10.1136\/bmjopen-2017-018335","article-title":"Using internet search data to predict new HIV diagnoses in China: A modelling study","volume":"8","author":"Zhang","year":"2018","journal-title":"BMJ Open"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/jdv.15200","article-title":"Medical needs and major complaints related to pruritus in Germany: A 4-year retrospective analysis using Google AdWords Keyword Planner","volume":"33","author":"Zink","year":"2019","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"e18581","DOI":"10.2196\/18581","article-title":"Googling for Ticks and Borreliosis in Germany: Nationwide Google Search Analysis From 2015 to 2018","volume":"22","author":"Scheerer","year":"2020","journal-title":"J. Med. Internet Res."},{"key":"ref_29","unstructured":"Statistische \u00c4mter des Bundes und der L\u00e4nder (2020, November 07). Statistik. Code: 12411. Inhalt: Fortschreibung des Bev\u00f6lkerungsstandes. Available online: https:\/\/www.regionalstatistik.de\/genesis\/online?language=de&sequenz=statistikTabellen&selectionname=12411#abreadcrumb."},{"key":"ref_30","unstructured":"Statistisches Bundesamt (2020, November 07). Genesis-online.12411-0015: Bev\u00f6lkerung: Kreise, Stichtag. Available online: https:\/\/www-genesis.destatis.de\/genesis\/online?operation=previous&levelindex=3&step=2&titel=Tabellenaufbau&levelid=1606564217864&levelid=1606564166560#abreadcrumb."},{"key":"ref_31","unstructured":"Statistische \u00c4mter des Bundes und der L\u00e4nder (2020, November 07). AI002-1: Regionalatlas Deutschland. Indikatoren des Themenbereichs \u201cBev\u00f6lkerung\u201d. Available online: https:\/\/www.regionalstatistik.de\/genesis\/online?language=de&sequenz=tabelleAufbau&selectionname=AI002-1#astructure."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Tizek, L., Schielein, M., R\u00fcth, M., St\u00e4nder, S., Pereira, M.P., Eberlein, B., Biedermann, T., and Zink, A. (2019). Influence of Climate on Google Internet Searches for Pruritus Across 16 German Cities: Retrospective Analysis. J. Med. Internet Res., 21.","DOI":"10.2196\/preprints.13739"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"797","DOI":"10.2340\/00015555-3214","article-title":"Interest in Skin Cancer in Urban Populations: A Retrospective Analysis of Google Search Terms in Nine Large German Cities","volume":"99","author":"Tizek","year":"2019","journal-title":"Acta Derm. Venereol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"674","DOI":"10.2340\/00015555-1159","article-title":"Prevalence, correlates and characteristics of chronic pruritus: A population-based cross-sectional study","volume":"91","author":"Matterne","year":"2011","journal-title":"Acta Derm. Venereol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1906","DOI":"10.1111\/jdv.14990","article-title":"Epidemiology of skin cancer in the German population: Impact of socioeconomic and geographic factors","volume":"32","author":"Augustin","year":"2018","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_36","first-page":"Doc03","article-title":"Prevalence and treatment of sexually transmitted infections in men followed by urologists in Germany\u2014A cross sectional study with 347,090 men","volume":"16","author":"Jacob","year":"2018","journal-title":"Ger. Med. Sci."},{"key":"ref_37","unstructured":"Deutsche STI-Gesellschaft (2020, November 07). Gesellschaft zur F\u00f6rderung der Sexuellen Gesundheit. Epidermiologie. Available online: https:\/\/www.dstig.de\/sexuelle-gesundheit\/epidemiologie.html."},{"key":"ref_38","unstructured":"Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (2020, November 07). Infektionen mit Chlamydia trachomatis. Available online: https:\/\/www.awmf.org\/uploads\/tx_szleitlinien\/059-005l_S2k_Chlamydia-trachomatis_Infektionen_2016-12.pdf."},{"key":"ref_39","unstructured":"Bundeszentrale f\u00fcr gesundheitliche Aufkl\u00e4rung (2020, November 07). Liebesleben. Available online: https:\/\/www.liebesleben.de\/fuer-alle\/sexuell-uebertragbare-infektionen\/arzt-zustaendig\/."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1108\/IntR-07-2016-0228","article-title":"Conversing and searching: The causal relationship between social media and web search","volume":"27","author":"Mukherjee","year":"2017","journal-title":"Internet Res."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1093\/jncimonographs\/lgt017","article-title":"Using Digital Surveillance to Examine the Impact of Public Figure Pancreatic Cancer Announcements on Media and Search Query Outcomes","volume":"2013","author":"Noar","year":"2013","journal-title":"JNCI Monogr."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"e19611","DOI":"10.2196\/19611","article-title":"Assessment of the Impact of Media Coverage on COVID-19-Related Google Trends Data: Infodemiology Study","volume":"22","author":"Anto","year":"2020","journal-title":"J. Med. Internet Res."},{"key":"ref_43","unstructured":"World Health Organization (2020, November 07). Antibiotic-Resistant Gonorrhoea on the Rise, New Drugs Needed. Available online: https:\/\/www.who.int\/news\/item\/07-07-2017-antibiotic-resistant-gonorrhoea-on-the-rise-new-drugs-needed."},{"key":"ref_44","unstructured":"Government Digital Service (2020, November 07). Public Health England. Research and Analysis. Multi-Drug Resistant Gonorrhoea in England: 2018, Available online: https:\/\/www.gov.uk\/government\/publications\/multi-drug-resistant-gonorrhoea-in-england-2018."},{"key":"ref_45","unstructured":"MDR (2020, November 07). Weltgesundheitsorganisation Medikamente gegen Gonorrh\u00f6 wirken bald nicht mehr. Available online: https:\/\/www.mdr.de\/wissen\/mensch-alltag\/gonorrhoe-102.html."},{"key":"ref_46","unstructured":"Bild (2020, November 07). Brite f\u00e4ngt sich Super-Tripper ein! Kann mir das auch passieren?. Available online: https:\/\/www.bild.de\/ratgeber\/gesundheit\/ratgeber\/tripper-antibiotikaresistenz-55243318.bild.html."},{"key":"ref_47","unstructured":"Welt (2020, November 07). Brite mit Super-Tripper infiziert\u2014Antibiotika unwirksam. Available online: https:\/\/www.welt.de\/gesundheit\/article174994196\/Brite-mit-Super-Tripper-infiziert-Antibiotika-unwirksam.html."},{"key":"ref_48","unstructured":"RTLII (2021, February 11). Folge 1478-Wird Jule wieder laufen k\u00f6nnen? Kevin hat einen Tripper. Available online: https:\/\/www.rtl2.de\/sendungen\/koeln-50667\/folge\/179956-staffel-7-folge-1478-kevin-hat-einen-tripper."},{"key":"ref_49","unstructured":"TVmovie (2021, February 07). Nach Sex bei BTN: Krankheits-Schock! 2017. Available online: https:\/\/www.tvmovie.de\/news\/nach-sex-bei-btn-krankheits-schock-96687."},{"key":"ref_50","unstructured":"S\u00fcddeutsche Zeitung (2020, November 07). Charlie Sheen ist HIV-Positiv. Available online: https:\/\/www.sueddeutsche.de\/panorama\/us-schauspieler-charlie-sheen-ist-hiv-positiv-1.2740911."},{"key":"ref_51","unstructured":"Das Erste (2020, November 07). Bristant. Forschern gelingt Durchbruch gegen AIDS. Available online: https:\/\/www.mdr.de\/brisant\/forschern-gelingt-durchbruch-gegen-aids-100.html."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"e128","DOI":"10.2196\/jmir.2934","article-title":"Use of the internet as a health information resource among French young adults: Results from a nationally representative survey","volume":"16","author":"Beck","year":"2014","journal-title":"J. Med. Internet Res."},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Nuti, S.V., Wayda, B., Ranasinghe, I., Wang, S., Dreyer, R.P., Chen, S.I., and Murugiah, K. (2014). The use of google trends in health care research: A systematic review. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0109583"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1552652","DOI":"10.1080\/16549716.2018.1552652","article-title":"Correlation between Google Trends on dengue fever and national surveillance report in Indonesia","volume":"12","author":"Husnayain","year":"2019","journal-title":"Glob. Health Action"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/jdv.15283","article-title":"Perspectives of online surveys in dermatology","volume":"33","author":"Arafa","year":"2019","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1037\/0003-066X.54.2.93","article-title":"Self-reports: How the questions shape the answers","volume":"54","author":"Schwarz","year":"1999","journal-title":"Am. Psychol."},{"key":"ref_57","unstructured":"Koch, W., and Frees, B. (2020, November 07). ARD\/ZDF-Onlinestudie 2017: Neun von zehn Deutschen Online. Available online: https:\/\/www.ard-zdf-onlinestudie.de\/files\/2017\/Artikel\/917_Koch_Frees.pdf."},{"key":"ref_58","unstructured":"European Centre for Disease Prevention and Control (2020, November 07). Chlamydia Infection\u2014Annual Epidemiological Report for 2017. Available online: https:\/\/www.ecdc.europa.eu\/en\/publications-data\/chlamydia-infection-annual-epidemiological-report-2017."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/18\/5\/2771\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:35:32Z","timestamp":1760160932000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/18\/5\/2771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,9]]},"references-count":58,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,3]]}},"alternative-id":["ijerph18052771"],"URL":"https:\/\/doi.org\/10.3390\/ijerph18052771","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,9]]}}}