{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T15:33:37Z","timestamp":1783006417251,"version":"3.54.5"},"reference-count":29,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T00:00:00Z","timestamp":1615420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Early surgical intervention in hip fractures is associated with lower complications. This study aimed to determine the appropriate operation time among Asian geriatric patients. The data of 1118 elderly patients with hip fracture at Mackay Memorial Hospital from 1 January 2011, to 31 July 2019, were retrospectively examined. Association between operation waiting time and the occurrence of complications was calculated using a cubic spline model. Significantly increased incidence of pneumonia, myocardial infarction, and heart failure was observed in 30 and 90 days when the patient\u2019s surgical waiting time exceeded 36 h. The incidence rates of pneumonia across the early and delayed groups within 30 and 90 days were 4.4% vs. 7.9%, and 6.2% vs. 10.7%, those of myocardial infarction were 3.0% vs. 7.2%, and 5.7% vs. 9.3%, and those of heart failure were 15.2% vs. 26.8%, and 16.2% vs. 28.5%. Deep vein thrombosis and pulmonary embolism were not associated with surgical delay. The overall 30-day mortality rate was 5.4%, and no significant difference was observed when the surgical waiting time exceeded 36 h. In summary, operation waiting time exceeding 36-h was associated with increased rates of pneumonia, myocardial infarction, and heart failure in Asian geriatric patients undergoing hip fracture surgery.<\/jats:p>","DOI":"10.3390\/ijerph18062848","type":"journal-article","created":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T05:38:22Z","timestamp":1615441102000},"page":"2848","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Associations between Hip Fracture Operation Waiting Time and Complications in Asian Geriatric Patients: A Taiwan Medical Center Study"],"prefix":"10.3390","volume":"18","author":[{"given":"Ching-Yi","family":"Shen","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Mackay Memorial Hospital, Taipei 104, Taiwan"},{"name":"Department of Medicine, Mackay Medical College, New Taipei City 252, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4747-2243","authenticated-orcid":false,"given":"Chien-Han","family":"Hsiao","sequence":"additional","affiliation":[{"name":"Department of Linguistics, Indiana University, Bloomington, IN 47405, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7859-2032","authenticated-orcid":false,"given":"Weide","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Mackay Memorial Hospital, Taipei 104, Taiwan"},{"name":"Department of Medicine, Mackay Medical College, New Taipei City 252, Taiwan"},{"name":"MacKay Junior College of Medicine, Nursing, and Management, Taipei 112, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Han","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Mackay Memorial Hospital, Taipei 104, Taiwan"},{"name":"Department of Medicine, Mackay Medical College, New Taipei City 252, Taiwan"},{"name":"MacKay Junior College of Medicine, Nursing, and Management, Taipei 112, Taiwan"},{"name":"Institute of Mechatronic Engineering, National Taipei University of Technology, Taipei 106, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tse-Hao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Mackay Memorial Hospital, Taipei 104, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1007\/s00198-004-1651-0","article-title":"High incidence rate of hip fracture in Taiwan: Estimated from a nationwide health insurance database","volume":"15","author":"Chie","year":"2004","journal-title":"Osteoporos. Int."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.jos.2017.06.003","article-title":"Survey of hip fractures in Japan: Recent trends in prevalence and treatment","volume":"22","author":"Hagino","year":"2017","journal-title":"J. Orthop. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.afos.2018.03.003","article-title":"An updated hip fracture projection in Asia: The Asian Federation of Osteoporosis Societies study","volume":"4","author":"Cheung","year":"2018","journal-title":"Osteoporos. Sarcopenia"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/j.bone.2012.02.633","article-title":"Prediction of survival, second fracture, and functional recovery following the first hip fracture surgery in elderly patients","volume":"50","author":"Kim","year":"2012","journal-title":"Bone"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1177\/2151458514555570","article-title":"Fragility hip fractures in elderly patients in bhubaneswar, India (2012\u20132014): A prospective multicenter study of 1031 elderly patients","volume":"6","author":"Dash","year":"2015","journal-title":"Geriatr. Orthop. Surg. Rehabil."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1001\/jama.2017.17606","article-title":"Association between wait Time and 30-Day Mortality in Adults Undergoing Hip Fracture Surgery","volume":"318","author":"Pincus","year":"2017","journal-title":"JAMA"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1016\/j.injury.2018.07.026","article-title":"Timing of surgery for hip fractures in the elderly: A retro-spective cohort study","volume":"49","author":"Sasabuchi","year":"2018","journal-title":"Injury"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s00068-016-0684-3","article-title":"Recommendations on hip fractures","volume":"42","author":"Wendt","year":"2016","journal-title":"Eur. J. Trauma Emerg. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"131","DOI":"10.5435\/JAAOS-D-14-00432","article-title":"Management of Hip Fractures in the Elderly","volume":"23","author":"Roberts","year":"2015","journal-title":"J. Am. Acad. Orthop. Surg."},{"key":"ref_10","unstructured":"R Core Team (2020). R: A Language and Environment for Statistical Computing, R Foundation for Statistical Computing."},{"key":"ref_11","unstructured":"RStudioTeam (2020). RStudio: Integrated Development for R., PBC."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Wickham, H. (2016). ggplot2: Elegant Graphics for Data Analysis, Springer.","DOI":"10.1007\/978-3-319-24277-4_9"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1038\/s41409-019-0679-x","article-title":"Cubic splines to model relationships between continuous variables and outcomes: A guide for clinicians","volume":"55","author":"Gauthier","year":"2019","journal-title":"Bone Marrow Transplant."},{"key":"ref_14","unstructured":"IBM Corp. (2019). IBM Spss Statistics for Windows, Version 26.0, IBM Corp."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1757-7241-16-7","article-title":"The Utstein template for uniform reporting of data following major trauma: A joint revision by SCANTEM, TARN, DGU-TR and RITG","volume":"16","author":"Ringdal","year":"2008","journal-title":"Scand. J. Trauma Resusc. Emerg. Med."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.injury.2020.11.011","article-title":"Trauma-registry survival outcome follow up: 30 days is mandatory and appears sufficient","volume":"52","author":"Brinck","year":"2021","journal-title":"Injury"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1538-7836.2004.01094.x","article-title":"Epidemiology of venous thromboem-bolism in Asian patients undergoing major orthopedic surgery without thromboprophylaxis. The smart study","volume":"3","author":"Leizorovicz","year":"2005","journal-title":"J. Thromb. Haemost."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/BLO.0b013e318156bfac","article-title":"The 2007 john charnley award. Factors leading to low prevalence of dvt and pulmonary embolism after THA: Analysis of genetic and prothrombotic factors","volume":"465","author":"Kim","year":"2007","journal-title":"Clin. Orthop. Relat. Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/s00776-009-1425-9","article-title":"Factors determining the 1-year survival after operated hip fracture: A hospital-based analysis","volume":"15","author":"Ho","year":"2010","journal-title":"J. Orthop. Sci."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s10195-015-0387-2","article-title":"Achieving hip fracture surgery within 36 h: An investigation of risk factors to surgical delay and recommendations for practice","volume":"17","author":"Aqil","year":"2015","journal-title":"J. Orthop. Traumatol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"361","DOI":"10.3928\/01477447-20160719-07","article-title":"Timing of Hip Fracture Surgery and 30-Day Outcomes","volume":"39","author":"Neufeld","year":"2016","journal-title":"Orthopedics"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s00402-017-2674-2","article-title":"Effect of causes of surgical delay on early and late mortality in patients with proximal hip fracture","volume":"137","author":"Cha","year":"2017","journal-title":"Arch. Orthop. Trauma Surg."},{"key":"ref_23","first-page":"374","article-title":"Early surgery for Hong Kong Chinese elderly patients with hip fracture reduces short-term and long-term mortality","volume":"23","author":"Liu","year":"2017","journal-title":"Hong Kong Med. J."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1097\/BOT.0000000000001043","article-title":"Early Surgery Confers 1-Year Mortality Benefit in Hip-Fracture Patients","volume":"32","author":"Maheshwari","year":"2018","journal-title":"J. Orthop. Trauma"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1097\/BOT.0000000000001306","article-title":"Delay in Hip Fracture Surgery Prolongs Postoperative Hospital Length of Stay but Does Not Adversely Affect Outcomes at 30 Days","volume":"32","author":"Mitchell","year":"2018","journal-title":"J. Orthop. Trauma"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.2106\/00004623-200309000-00004","article-title":"Internal fixation compared with arthroplasty for displaced fractures of the femoral neck. A meta-analysis","volume":"85","author":"Bhandari","year":"2003","journal-title":"J. Bone Joint Surg. Am."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1056\/NEJMcp1611090","article-title":"Management of Acute Hip Fracture","volume":"377","author":"Bhandari","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"609","DOI":"10.3109\/17453674.2012.747926","article-title":"Is mortality after hip fracture associated with surgical delay or admission during weekends and public holidays? A retrospective study of 38,020 patients","volume":"83","author":"Daugaard","year":"2012","journal-title":"Acta Orthop."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1093\/intqhc\/mzw037","article-title":"Off-hours admission and quality of hip fracture care: A nationwide cohort study of performance measures and 30-day mortality","volume":"28","author":"Kristiansen","year":"2016","journal-title":"Int. J. Qual. 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