{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:54:03Z","timestamp":1760234043182,"version":"build-2065373602"},"reference-count":45,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T00:00:00Z","timestamp":1616544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Mucosal melanomas of the head and neck region are uncommon pathologies that can affect the oral cavity, and are characterized by a high rate of mortality. Considering the lack of knowledge regarding risk and prognostic factors, current best clinical practice is represented by a large surgical excision with disease-free margins, eventually associated with a reconstructive flap. Indeed, given the frequent necessity of postoperative radiotherapy and fast healing process, a reconstruction of the surgical gap is advisable. Even if several flaps have been most commonly used, the submental island flap represents a valid alternative thanks to local advantages and similar oncologic outcomes compared to free flaps.<\/jats:p>","DOI":"10.3390\/ijerph18073341","type":"journal-article","created":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T15:42:19Z","timestamp":1616600539000},"page":"3341","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Mucosal Melanoma of the Hard Palate: Surgical Treatment and Reconstruction"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9163-5540","authenticated-orcid":false,"given":"Stefano","family":"Bondi","sequence":"first","affiliation":[{"name":"Otorhinolaryngology\u2014Head &amp; Neck Surgery Department, San Raffaele Hospital, University Vita-Salute, 20100 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4805-4908","authenticated-orcid":false,"given":"Alessandro","family":"Vinciguerra","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology\u2014Head &amp; Neck Surgery Department, San Raffaele Hospital, University Vita-Salute, 20100 Milano, Italy"},{"name":"School of Medicine, Vita-Salute San Raffaele University, 20100 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3053-8832","authenticated-orcid":false,"given":"Alessandra","family":"Lissoni","sequence":"additional","affiliation":[{"name":"School of Medicine, Vita-Salute San Raffaele University, 20100 Milano, Italy"},{"name":"Department of Dentistry and Stomatology IRCCS San Raffaele Hospital, University Vita-Salute, 20100 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Rizzo","sequence":"additional","affiliation":[{"name":"Pathology Unit, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, 20100 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Barbieri","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology\u2014Head &amp; Neck Surgery Department, San Raffaele Hospital, University Vita-Salute, 20100 Milano, Italy"},{"name":"School of Medicine, Vita-Salute San Raffaele University, 20100 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7447-0994","authenticated-orcid":false,"given":"Pietro","family":"Indelicato","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology\u2014Head &amp; Neck Surgery Department, San Raffaele Hospital, University Vita-Salute, 20100 Milano, Italy"},{"name":"School of Medicine, Vita-Salute San Raffaele University, 20100 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3226-8242","authenticated-orcid":false,"given":"Silvio","family":"Abati","sequence":"additional","affiliation":[{"name":"School of Medicine, Vita-Salute San Raffaele University, 20100 Milano, Italy"},{"name":"Department of Dentistry and Stomatology IRCCS San Raffaele Hospital, University Vita-Salute, 20100 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.critrevonc.2017.01.019","article-title":"Mucosal melanoma of the head and neck","volume":"112","author":"Ascierto","year":"2017","journal-title":"Crit. 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