{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T04:23:51Z","timestamp":1772252631673,"version":"3.50.1"},"reference-count":35,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2021,6,18]],"date-time":"2021-06-18T00:00:00Z","timestamp":1623974400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>The optic nerve sheath diameter (ONSD) can help predict the neurologic outcomes of patients with post-cardiac arrest (CA) return of spontaneous circulation (ROSC). We aimed to investigate the effect of ONSD changes before and after CA on neurologic outcomes in patients with ROSC after CA using brain computed tomography (CT). The study included patients hospitalized after CA, who had undergone pre- and post-CA brain CT between January 2001 and September 2020. The patients were divided into good and poor neurologic outcome (GNO and PNO, respectively) groups based on their neurologic outcome at hospital discharge. We performed between-group comparisons of the amount and rate of ONSD changes in brain CT and calculated the area under the curve (AUC) to determine their predictive value for neurologic outcomes. Among the 96 enrolled patients, 25 had GNO. Compared with the GNO group, the PNO group showed a significantly higher amount (0.30 vs. 0.63 mm; p = 0.030) and rate (5.26 vs. 12.29%; p = 0.041) of change. The AUC for predicting PNO was 0.64 (95% confidence interval = 0.53\u20130.73; p = 0.04), and patients with a rate of ONSD change &gt;27.2% had PNO with 100% specificity and positive predictive value. Hence, ONSD changes may predict neurologic outcomes in patients with post-CA ROSC.<\/jats:p>","DOI":"10.3390\/ijerph18126567","type":"journal-article","created":{"date-parts":[[2021,6,18]],"date-time":"2021-06-18T11:19:20Z","timestamp":1624015160000},"page":"6567","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Predictive Utility of Changes in Optic Nerve Sheath Diameter after Cardiac Arrest for Neurologic Outcomes"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5700-3331","authenticated-orcid":false,"given":"Heekyung","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Hanyang University Guri Hospital, 153, Gyeongchunro-ro, Guri, Gyeonggi-do 11923, Korea"},{"name":"Department of Emergency Medicine, Graduate School of Medicine, Hanyang University, Seoul 04763, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joonkee","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Hanyang University Guri Hospital, 153, Gyeongchunro-ro, Guri, Gyeonggi-do 11923, Korea"},{"name":"Department of Emergency Medicine, Graduate School of Medicine, Hanyang University, Seoul 04763, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3203-1672","authenticated-orcid":false,"given":"Hyungoo","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Hanyang University Guri Hospital, 153, Gyeongchunro-ro, Guri, Gyeonggi-do 11923, Korea"},{"name":"Department of Emergency Medicine, College of Medicine, Hanyang University, 222, Wangsimni-ro, Seongdong-gu, Seoul 04763, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changsun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Hanyang University Guri Hospital, 153, Gyeongchunro-ro, Guri, Gyeonggi-do 11923, Korea"},{"name":"Department of Emergency Medicine, College of Medicine, Hanyang University, 222, Wangsimni-ro, Seongdong-gu, Seoul 04763, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyuk-Joong","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Hanyang University Guri Hospital, 153, Gyeongchunro-ro, Guri, Gyeonggi-do 11923, Korea"},{"name":"Department of Emergency Medicine, College of Medicine, Hanyang University, 222, Wangsimni-ro, Seongdong-gu, Seoul 04763, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo-Seung","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Hanyang University Guri Hospital, 153, Gyeongchunro-ro, Guri, Gyeonggi-do 11923, Korea"},{"name":"Department of Emergency Medicine, College of Medicine, Hanyang University, 222, Wangsimni-ro, Seongdong-gu, Seoul 04763, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1007\/BF01720676","article-title":"Prognostic significance of early intracranial and cerebral perfusion pressures in post-cardiac arrest anoxic coma","volume":"17","author":"Gueugniaud","year":"1991","journal-title":"Intensive Care Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1161\/01.STR.32.1.128","article-title":"Autoregulation of cerebral blood flow in patients resuscitated from cardiac arrest","volume":"32","author":"Sundgreen","year":"2001","journal-title":"Stroke"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/j.resuscitation.2011.04.001","article-title":"Association between a quantitative CT scan measure of brain edema and outcome after cardiac arrest","volume":"82","author":"Metter","year":"2011","journal-title":"Resuscitation"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1097\/00003246-199706000-00013","article-title":"Delayed hyperemia causing intracranial hypertension after cardiopulmonary resuscitation","volume":"25","author":"Iida","year":"1997","journal-title":"Crit. 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