{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T12:34:57Z","timestamp":1780403697072,"version":"3.54.1"},"reference-count":57,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T00:00:00Z","timestamp":1624492800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Taichung Hospital, Ministry of Health and Welfare, Taichung, Taiwan","award":["TAIC107-04"],"award-info":[{"award-number":["TAIC107-04"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>This article investigates the effects of continuous positive airway pressure (CPAP) on hearing impairment in sensorineural hearing loss (SNHL) patients with sleep-disordered breathing (SDB). This retrospective and observational study took place from September 2016 to February 2021, accumulating 77 subjects with SNHL and SDB (60.7 \u00b1 11.1 years). Of which, 28 received CPAP treatment (63.0 \u00b1 8.5 years). In our methodology, hearing thresholds at low, medium, high, and average frequencies are assessed by pure-tone audiometry at baseline (BL), three (3 m), six (6 m), and 12 (12 m) months. Our results show that the BL of at least three frequencies in all subjects is positively associated with old age, males, smoking, alcohol, coronary artery disease, hypertension, and apnea-hypopnea index [AHI] (all p &lt; 0.05). Moreover, low, medium, and average frequencies are negatively correlated at CPAP-6 m (\u22125.60 \u00b1 2.33, \u22125.82 \u00b1 2.56, and \u22125.10 \u00b1 2.26 dB; all p &lt; 0.05) and CPAP-12 m (\u22127.97 \u00b1 2.74, \u22128.15 \u00b1 2.35, and \u22126.67 \u00b1 2.37 dB; all p &lt; 0.01) against corresponding measures of CPAP-BL. High, medium, and average frequencies positively correlated with age (p &lt; 0.001 for high and average frequencies and &lt;0.01 for medium frequencies). We conclude that in SNHL patients with SDB, hearing thresholds at low and medium frequencies improves under CPAP use after six months, which persists at least to the end of one year.<\/jats:p>","DOI":"10.3390\/ijerph18136768","type":"journal-article","created":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T04:24:36Z","timestamp":1624508676000},"page":"6768","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["CPAP Treatment Improves Pure Tone Audiometry Threshold in Sensorineural Hearing Loss Patients with Sleep-Disordered Breathing"],"prefix":"10.3390","volume":"18","author":[{"given":"Jessie Chao-Yun","family":"Chi","sequence":"first","affiliation":[{"name":"Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan"},{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Taichung Hospital, Ministry of Health and Welfare, Taichung 403, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8393-8349","authenticated-orcid":false,"given":"Shin-Da","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Graduate Institute of Rehabilitation Science, China Medical University, Taichung 40402, Taiwan"},{"name":"Department of Occupational Therapy, Asia University, Taichung 413, Taiwan"},{"name":"School of Rehabilitation Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren-Jing","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Medical Image and Radiological Sciences, Chung Shan Medical University, Taichung 40201, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching-Hsiang","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, Chung Shan Medical University, Taichung 40201, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6885-7885","authenticated-orcid":false,"given":"Stanley Yung","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Stanford University School of Medicine, Stanford, CA 94305-5101, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yih-Jeng","family":"Tsai","sequence":"additional","affiliation":[{"name":"School of Medicine, Fu-Jen Catholic University, New Taipei City 24205, Taiwan"},{"name":"Department of Otolaryngology Head and Neck Surgery, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111045, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Han","family":"Fu","sequence":"additional","affiliation":[{"name":"Graduate Institute of Photonics and Optoelectronics, National Taiwan University, Taipei 10617, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Ting","sequence":"additional","affiliation":[{"name":"Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan"},{"name":"Department of Physical Medicine and Rehabilitation, Chung Shan Medical University Hospital, Taichung 40201, Taiwan"},{"name":"Sleep Medicine Center, Chung Shan Medical University Hospital, Taichung 40201, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,24]]},"reference":[{"key":"ref_1","unstructured":"Peter, C., and Weber, S.K. 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