{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:36:35Z","timestamp":1790757395161,"version":"4.1.0"},"reference-count":41,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T00:00:00Z","timestamp":1627862400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>A number of systemic diseases including hematological disorders have manifestations in the oral cavity region. These manifestations may often represent early signs of the underlying hematopoietic disease and occur frequently in leukemia. Despite the fact that leukemia has long been known to be associated with oral health deterioration, the available literature on this topic consists mostly of case reports, without data to conclude these. The aim of the study was to assess dentition state in leukemic patients during one cycle of chemotherapy and its correlation with blood parameters. The study included 102 adults treated because of leukemia at the Clinic of Haemato-Oncology and Bone Marrow Transplantation at the university hospital in Lublin, Poland. The sample group consisted of 51 women and 51 men aged 22 to 72 (54.07 \u00b1 10.33) with following diagnoses: Acute myelogenous leukemia (AML)\u201455 patients (53.92%), Chronic lymphocytic leukemia (CLL)\u201417 patients (16.67%), Acute lymphoblastic leukemia (ALL)\u201416 patients (15.69%), Chronic myelogenous leukemia (CML)\u201410 patients (9.80%), Acute promyelocytic leukemia (APL) \u20143 patients (2.94%), Chronic hairy cell leukemia (HCL)\u20141 patient (0.98%). DMFT index was used to assess dentition state. After the cycle of chemotherapy, their dentition state changed in terms of decayed, missing and filled teeth and correlated with hematological parameters. Adult patients with leukemia have high dental treatment needs, and high number of missing teeth; thus, a comprehensive and fast dental treatment is necessary to avoid systemic complications and ensure better quality of life.<\/jats:p>","DOI":"10.3390\/ijerph18158193","type":"journal-article","created":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T08:16:39Z","timestamp":1627978599000},"page":"8193","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Changes of Dentition State in Leukemic Patients during Chemotherapy"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2156-5698","authenticated-orcid":false,"given":"Maja","family":"Ptasiewicz","sequence":"first","affiliation":[{"name":"Department of Oral Medicine, Medical University of Lublin, ul. Chod\u017aki 6, 20-093 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5447-8662","authenticated-orcid":false,"given":"Pawe\u0142","family":"Maksymiuk","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Medical University of Lublin, ul. Chod\u017aki 6, 20-093 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1730-4540","authenticated-orcid":false,"given":"Renata","family":"Cha\u0142as","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Medical University of Lublin, ul. Chod\u017aki 6, 20-093 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,8,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"230","DOI":"10.2174\/1874210601812010230","article-title":"Long-Term effects of acute Myeloid Leukemia Treatment on the Oral System in Pediatric Patient","volume":"12","author":"Lupi","year":"2018","journal-title":"Open Dent. J."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Zimmermann, C., Meurer, M.I., Grando, L.J., Gonzaga Del Moral, J.\u00c2., da Silva Rath, I.B., and Schaefer Tavares, S. (2015). Dental treatment in patients with leukemia. J. Oncol., 2015.","DOI":"10.1155\/2015\/571739"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1038\/nrc.2016.63","article-title":"The genetics and mechanisms of T cell acute lymphoblastic leukaemia","volume":"16","author":"Belver","year":"2016","journal-title":"Nat. Rev. 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