{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:18:00Z","timestamp":1760235480888,"version":"build-2065373602"},"reference-count":43,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T00:00:00Z","timestamp":1629849600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["19K08361, 20H04119, 20K11644, 21H03372"],"award-info":[{"award-number":["19K08361, 20H04119, 20K11644, 21H03372"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>(1) Aim: Hepatic fibrosis is a prognostic factor for disease progression in non-alcoholic fatty liver disease (NAFLD). We aimed to determine the relationships between diet, physical activity, and the progression of liver fibrosis. (2) Methods: The 349 participants were categorized by their FibroScan-aspartate aminotransferase score, and they completed a questionnaire regarding their diet and physical activity. (3) Results: There were 233 patients in the negative-on-screening group, 78 in the gray zone group, and 38 in the positive-on-screening group. The frequencies of consumption of soybeans and soybean products and of light-colored vegetables were lower in the positive group; whereas the frequencies of consumption of snack food and fried sweets, jelly and pudding, fried food, and butter, lard, and beef tallow were higher. The odds ratios for the fibrosis progression in patients who consumed fried food \u22654 times\/week was 2.21. The positive group also showed lower physical activity level (PAL) and exercise (Ex, metabolic equivalents for tasks (METs)\/hour\/week). The patients who undertook Ex at &gt;7.5 had an odds ratio of 0.21 for the fibrosis progression. (4) Conclusion: High consumption of fried food and low Ex are risk factors for the fibrosis progression in NAFLD.<\/jats:p>","DOI":"10.3390\/ijerph18178918","type":"journal-article","created":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T04:24:27Z","timestamp":1629865467000},"page":"8918","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Relationships of Dietary Habits and Physical Activity Status with Non-Alcoholic Fatty Liver Disease Featuring Advanced Fibrosis"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9398-738X","authenticated-orcid":false,"given":"Yoshito","family":"Yabe","sequence":"first","affiliation":[{"name":"Medical Sciences, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taeho","family":"Kim","sequence":"additional","affiliation":[{"name":"The Center for Sports Medicine and Health Sciences, Tsukuba University Hospital, Tsukuba 305-8576, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sechang","family":"Oh","sequence":"additional","affiliation":[{"name":"Division of Radiology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Shida","sequence":"additional","affiliation":[{"name":"Medical Technology and Science, International University of Health and Welfare, Narita 286-8686, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natsumi","family":"Oshida","sequence":"additional","affiliation":[{"name":"Division of Laboratory Medicine, Tsukuba University Hospital, Tsukuba 305-8576, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoyuki","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kosuke","family":"Okada","sequence":"additional","affiliation":[{"name":"Tsukuba Preventive Medicine Research Center, University of Tsukuba Hospital, Tsukuba 305-8576, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Someya","sequence":"additional","affiliation":[{"name":"The Center for Sports Medicine and Health Sciences, Tsukuba University Hospital, Tsukuba 305-8576, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Mizokami","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichi","family":"Shoda","sequence":"additional","affiliation":[{"name":"Medical Sciences, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,8,25]]},"reference":[{"key":"ref_1","first-page":"491","article-title":"Changes in Non-alcoholic Fatty Liver Disease (NAFLD) Frequency and Examination Results in Health Check-ups Over 20-year Period (1996 through 2015)","volume":"32","author":"Akihiro","year":"2017","journal-title":"Ningen Dock"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1464-5491.2007.02025.x","article-title":"Non-alcoholic fatty liver disease, the metabolic syndrome and the risk of cardiovascular disease: The plot thickens","volume":"24","author":"Targher","year":"2007","journal-title":"Diabet. 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