{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:32:26Z","timestamp":1790382746139,"version":"4.1.0"},"reference-count":55,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T00:00:00Z","timestamp":1630886400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Hopitaux universitaires de strasbourg","award":["AAPJC 2013 HUS N\u00b0 5502"],"award-info":[{"award-number":["AAPJC 2013 HUS N\u00b0 5502"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Periodontal treatment could be worsened by risk factors. Depression and anxiety have been suggested as potentially influencing periodontal treatment outcomes. The aim of this study was to determine their association with non-surgical periodontal treatment outcomes in patients with generalized severe periodontitis (stage III\/IV generalized periodontitis) at 6 months. A total of 68 patients diagnosed with generalized severe periodontitis were treated with scaling and root planing (SRP) and were followed at 3 and 6 months. The data of the 54 patients that followed the entire protocol were considered for analysis. Depression and anxiety levels were determined at baseline by the Beck Depression Inventory (BDI) and State-Trait Inventory (STAI) questionnaires. The association between psychological scores and periodontal parameters was evaluated by multivariate analysis. At 3 and 6 months, SRP induced an improvement for all periodontal parameters (plaque index (PI), bleeding on probing (BOP), periodontal probing depth (PPD) and clinical attachment loss (CAL)). BDI and STAI scores were associated with the evolution of PI, BOP, mean PPD and number of sites with PPD &gt; 3 mm and with CAL &gt; 3 mm. Depression and anxiety should be considered as risk factors for SRP and the identification of at-risk patients should be performed using well-established tools.<\/jats:p>","DOI":"10.3390\/ijerph18179394","type":"journal-article","created":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T21:47:38Z","timestamp":1630964858000},"page":"9394","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Influence of Depression and Anxiety on Non-Surgical Periodontal Treatment Outcomes: A 6-Month Prospective Study"],"prefix":"10.3390","volume":"18","author":[{"given":"Catherine","family":"Petit","sequence":"first","affiliation":[{"name":"Facult\u00e9 de Chirurgie Dentaire, Periodontology, Universit\u00e9 de Strasbourg, 67000 Strasbourg, France"},{"name":"P\u00f4le de M\u00e9decine et Chirurgie Bucco-Dentaires, Hopitaux Universitaires de Strasbourg, 67000 Strasbourg, France"},{"name":"INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine, F\u00e9d\u00e9ration de M\u00e9decine Translationnelle de Strasbourg (FMTS), 67000 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Anadon-Rosinach","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de Chirurgie Dentaire, Periodontology, Universit\u00e9 de Strasbourg, 67000 Strasbourg, France"},{"name":"P\u00f4le de M\u00e9decine et Chirurgie Bucco-Dentaires, Hopitaux Universitaires de Strasbourg, 67000 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Tuzin","sequence":"additional","affiliation":[{"name":"Groupe M\u00e9thode en Recherche Clinique, Service de Sant\u00e9 Publique, H\u00f4pitaux Universitaires de Strasbourg, 67000 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7336-5930","authenticated-orcid":false,"given":"Jean-Luc","family":"Davideau","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de Chirurgie Dentaire, Periodontology, Universit\u00e9 de Strasbourg, 67000 Strasbourg, France"},{"name":"P\u00f4le de M\u00e9decine et Chirurgie Bucco-Dentaires, Hopitaux Universitaires de Strasbourg, 67000 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7988-2290","authenticated-orcid":false,"given":"Olivier","family":"Huck","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de Chirurgie Dentaire, Periodontology, Universit\u00e9 de Strasbourg, 67000 Strasbourg, France"},{"name":"P\u00f4le de M\u00e9decine et Chirurgie Bucco-Dentaires, Hopitaux Universitaires de Strasbourg, 67000 Strasbourg, France"},{"name":"INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine, F\u00e9d\u00e9ration de M\u00e9decine Translationnelle de Strasbourg (FMTS), 67000 Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/prd.12296","article-title":"The Role of the Microbiota in Periodontal Disease","volume":"83","author":"Curtis","year":"2020","journal-title":"Periodontol. 2000"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"GBD 2017 Oral Disorders Collaborators, Bernabe, E., Marcenes, W., Hernandez, C.R., Bailey, J., Abreu, L.G., Alipour, V., Amini, S., Arabloo, J., and Arefi, Z. 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