{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:28:19Z","timestamp":1790814499661,"version":"4.1.0"},"reference-count":28,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2021,10,2]],"date-time":"2021-10-02T00:00:00Z","timestamp":1633132800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008976","name":"University of Venda","doi-asserted-by":"publisher","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}],"id":[{"id":"10.13039\/501100008976","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Despite the implementation of global plans to end tuberculosis (TB), this disease remains a major cause of ill-health and is the second leading cause of death. In 2019, globally, an estimated 10.0 million people fell ill and about 1.4 million died of TB. During the same year, South Africa was among the eight countries with the highest tuberculosis burden, contributing to two-thirds of the world\u2019s total. Due to the high burden of the human immunodeficiency virus (HIV) epidemic, TB in South Africa is a major public health problem. Limpopo is amongst the provinces that are hardest hit by TB and HIV in South Africa. Therefore, using a quantitative descriptive design, this study assessed the knowledge, beliefs, and perceptions of TB and TB treatment amongst TB patients in the Limpopo Province. A systematic random sampling method was used to sample 207 TB patients who agreed in writing to be part of the study. Data were collected using a self-administered questionnaire, however, about 3.9% of participants who could not read were assisted by the main researcher and health professional. About 33% of the participants with primary education were also assisted to clarify any questions that were not clear to them. Data were analyzed using the Statistical Package for Social Sciences\u00ae version 26.0. Validity and reliability of the instrument was ensured, and ethical considerations were observed in this study. The research findings revealed that about 93.25% respondents only came to know they had TB after diagnosis. About 75% indicated that they had visited faith healers and only 2% acknowledged that they had visited traditional healers after diagnosis. A total of 76% of the respondents stated that they strongly believed in their culture and religion. These findings highlight the need for health education efforts to strengthen accurate information to improve TB knowledge and correct misconceptions about TB among patients within the community.<\/jats:p>","DOI":"10.3390\/ijerph181910404","type":"journal-article","created":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T09:24:15Z","timestamp":1633339455000},"page":"10404","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Knowledge, Beliefs, and Perceptions of TB and Its Treatment amongst TB Patients in the Limpopo Province, South Africa"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9949-4439","authenticated-orcid":false,"given":"Hulisani","family":"Matakanye","sequence":"first","affiliation":[{"name":"Department of Public Health, School of Health Sciences, University of Venda, Thohoyandou 0950, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takalani Grace","family":"Tshitangano","sequence":"additional","affiliation":[{"name":"Department of Public Health, School of Health Sciences, University of Venda, Thohoyandou 0950, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jabu Tsakani","family":"Mabunda","sequence":"additional","affiliation":[{"name":"Department of Public Health, School of Health Sciences, University of Venda, Thohoyandou 0950, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thelmah Xavela","family":"Maluleke","sequence":"additional","affiliation":[{"name":"Department of Public Health, School of Health Care Sciences, University of Limpopo, Sovenga 0727, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,2]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (WHO) (2016). Global Tuberculosis Report 2016, WHO."},{"key":"ref_2","unstructured":"World Health Organization (WHO) (2020). Global Tuberculosis Report 2020, WHO. Reviewed in 14 October 2020."},{"key":"ref_3","unstructured":"World Health Organization (WHO) (2020, May 20). Tuberculosis Factsheet. Available online: http:\/\/www.who.int\/mediacentre\/factsheets\/fs104\/en\/."},{"key":"ref_4","unstructured":"World Health Organization (WHO) (2021, February 25). Coronavirus Disease (COVID-19) Dashboard. Available online: https:\/\/covid19.who.intExternalLink."},{"key":"ref_5","unstructured":"National Department of Health (2017). Department of Health Annual Report 2017, Department of Health."},{"key":"ref_6","unstructured":"World Health Organization (WHO) (2018). Global Tuberculosis Report, WHO. Reviewed on 20 November 2018."},{"key":"ref_7","unstructured":"Health System Trust (2017). District Health Barometer 2015\/16, Health System Trust."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"287","DOI":"10.11604\/pamj.2018.30.287.14836","article-title":"Knowledge and perceptions of tuberculosis among patients in a pastoralist community in Kenya: A qualitative study","volume":"30","author":"Mbuthia","year":"2018","journal-title":"Pan Afr. Med. J."},{"key":"ref_9","first-page":"1","article-title":"Adherence to treatment and related factors among patients with chronic conditions in primary care: A cross-sectional study","volume":"20","author":"Adams","year":"2019","journal-title":"BMC Fam. Pract."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"855","DOI":"10.4314\/ahs.v14i4.13","article-title":"Socio-demographic factors affecting knowledge level of Tuberculosis patients in Rajshahi City, Bangladesh","volume":"14","author":"Mondal","year":"2015","journal-title":"Afr. Health Sci."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Tolossa, D., Medhin, G., and Legesse, M. (2014). Community knowledge, attitude, and practices towards tuberculosis in Shinile town, Somali regional state, eastern Ethiopia: A cross-sectional study. BMC Public Health, 14.","DOI":"10.1186\/1471-2458-14-804"},{"key":"ref_12","first-page":"1","article-title":"Tuberculosis Treatment Non-Adherence and Lost to Follow Up among TB Patients with or without HIV in Developing Countries: A Systematic Review","volume":"44","author":"Tola","year":"2015","journal-title":"Iran. J. Public Health"},{"key":"ref_13","unstructured":"Centers for Disease Control and Prevention (2020, January 04). National Center for HIV\/AIDS, Viral Hepatitis, STD, and TB Prevention. 1600 Clifton Road Atlanta, GA 30329-4027 USA-CDC-INFO (800-232-4636), TTY: 888-232-6348, Available online: http:\/\/www.cdc.gov\/mmwr."},{"key":"ref_14","unstructured":"World Health Organization (2015). Global Tuberculosis Report, World Health Organization. [20th ed.]. Reviewed in March 2017."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1108\/QMR-04-2013-0024","article-title":"Conducting case study research in non-profit organisations","volume":"17","author":"Singh","year":"2014","journal-title":"Qual. Mark. Res. Int. J."},{"key":"ref_16","unstructured":"Creswell, J.W. (2014). Research Design: Qualitative, Quantitative and Mixed Methods Approaches, Sage. [4th ed.]."},{"key":"ref_17","unstructured":"De Vos, A.S., Strydom, H., Foeche, C.B., and Delport, C.S.L. (2011). Research at Grass Roots: For the Social Sciences and Human Service Professions, Van Schaik Publishers. [4th ed.]."},{"key":"ref_18","unstructured":"World Health Organization (2013). Global Tuberculosis Report 2013, World Health Organization."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ijid.2016.11.407","article-title":"Factors influencing treatment default among tuberculosis patients in a high burden province of South Africa","volume":"54","author":"Kigozi","year":"2017","journal-title":"Int. J. Infect. Dis."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"643","DOI":"10.4103\/2249-4863.222052","article-title":"Diagnostic delay and associated factors among patients with pulmonary tuberculosis in Kerala","volume":"6","author":"Paramasivam","year":"2017","journal-title":"J. Fam. Med. Prim. Care"},{"key":"ref_21","unstructured":"Mugoni, P.C. (2019). (Re) Positioning Communication for Enhanced Multidrug-Resistant Tuberculosis Treatment Adherence in South Africa: Towards an Integrated Communication Model for Young Women, University of Kwazulu Natal. Centre for Communication, Media, and Society."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12992-019-0459-9","article-title":"Perspectives on TB patients\u2019 care and support: A qualitative study conducted in Accra Metropolis, Ghana","volume":"15","author":"Gyimah","year":"2019","journal-title":"Glob. Health"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Viney, K.A., Johnson, P., Tagaro, M., Fanai, S., Linh, N.N., Kelly, P., Harley, D., and Sleigh, A. (2014). Tuberculosis patients\u2019 knowledge and beliefs about tuberculosis: A mixed methods study from the Pacific Island nation of Vanuatu. BMC Public Health, 14.","DOI":"10.1186\/1471-2458-14-467"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"315","DOI":"10.2174\/1874944501912010315","article-title":"\u201cI Visited a Traditional Healer Because I Felt I wasn\u2019t Getting any Better by Using Active Antiretroviral\u201d. Understanding Cultural Imperatives in the Context of Adherence to Highly Active Antiretroviral Therapy","volume":"12","author":"Ondwela","year":"2019","journal-title":"Open Public Health J."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"7","DOI":"10.4102\/phcfm.v8i2.981","article-title":"Needs assessment for adapting TB directly observed treatment intervention programme in Limpopo Province, South Africa: A community-based participatory research approach","volume":"8","author":"Mabunda","year":"2016","journal-title":"Afr. J. Prim. Health Care Fam. Med."},{"key":"ref_26","first-page":"1","article-title":"Severe Skin Rash and Liver Toxic Effects Caused By First-Line Anti-Tuberculosis Drugs: A Case Report","volume":"5","author":"Guo","year":"2017","journal-title":"Int. J. Complement Altern. Med."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Diefenbach-Elstob, T., Plummer, D., Dowi, R., Wamagi, S., Gula, B., Siwaeya, K., Pelowa, D., Siba, P., and Warner, J. (2017). The social determinants of tuberculosis treatment adherence in a remote region of Papua New Guinea. BMC Public Health, 17.","DOI":"10.1186\/s12889-016-3935-7"},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Mindachew, M., Deribew, A., Memiah, P., and Biadgilign, S. (2014). Perceived barriers to the implementation of Isoniazid preventive therapy for people living with HIV in resource constrained settings: A qualitative study. Pan Afr. Med. J., 17.","DOI":"10.11604\/pamj.2014.17.26.2641"}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/18\/19\/10404\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:08:56Z","timestamp":1760166536000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/18\/19\/10404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,2]]},"references-count":28,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2021,10]]}},"alternative-id":["ijerph181910404"],"URL":"https:\/\/doi.org\/10.3390\/ijerph181910404","relation":{},"ISSN":["1660-4601"],"issn-type":[{"value":"1660-4601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,2]]}}}