{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T09:21:31Z","timestamp":1770888091779,"version":"3.50.1"},"reference-count":41,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T00:00:00Z","timestamp":1634083200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Objectives: To investigate the relationship between the defects and symptoms caused by myelomeningocele (MMC) and quality of life. Design: A cross-sectional questionnaire survey. Methods: The subjects were 52 parents of children with MMC. Structured questionnaires were used: the Pediatric Quality of Life Inventory 4.0 Generic Core Scales (PedsQLTM 4.0) and a Study-Specific Questionnaire (SSQ). Results: The overall PedsQLTM 4.0 score was 56.4 (SD \u00b1 14.7). A strong, significant negative correlation was found between the children\u2019s age and emotional functioning. Functioning in this area deteriorated with age by a mean of 1.5 points per year of age. Children with no hydrocephalus functioned significantly better than those with this defect in the physical, social, and school areas (p &lt; 0.05). Foot deformities significantly (p = 0.033) adversely affected the children\u2019s physical functioning. Living in a single-parent family had no statistically significant impact on functioning in any of the areas analyzed (p &gt; 0.05). Conclusion: Understanding the QoL of children with MMC and identifying its determinants may help in planning interventions to minimize the adverse impact of the illness.<\/jats:p>","DOI":"10.3390\/ijerph182010756","type":"journal-article","created":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T21:36:15Z","timestamp":1634160975000},"page":"10756","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["The Quality of Life of Children with Myelomeningocele: A Cross-Sectional Preliminary Study"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1727-3235","authenticated-orcid":false,"given":"Anna","family":"Rozensztrauch","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology, Wroclaw Medical University, 50-367 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdalena","family":"Iwa\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Neonatology, Wroclaw Medical University, 50-367 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6291-1577","authenticated-orcid":false,"given":"Maciej","family":"Bag\u0142aj","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Propaedeutic of Pediatrics and Rare Disorders, Wroclaw Medical University, 50-367 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/ddrr.91","article-title":"Optimizing health care for children with spina bifida","volume":"16","author":"Liptak","year":"2010","journal-title":"Dev. 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