{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T12:38:58Z","timestamp":1765888738483,"version":"build-2065373602"},"reference-count":49,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T00:00:00Z","timestamp":1635897600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","award":["NIHR200415"],"award-info":[{"award-number":["NIHR200415"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Increasing numbers of people in England experience homelessness, substance use, and repeated offending (known as \u2018severe and multiple disadvantage\u2019; SMD). Populations experiencing SMD often have extremely poor oral health, which is closely inter-linked with high levels of substance use, smoking, and poor diet. This study aims to undertake an evidence synthesis to identify the effectiveness, resource requirements, and factors influencing the implementation and acceptability of oral health and related health behaviour interventions in adults experiencing SMD. Two systematic reviews will be conducted using mixed-methods. Review 1 will investigate the effectiveness and resource implications of oral health and related health behaviours (substance use, smoking, diet) interventions; Review 2 will investigate factors influencing the implementation of such interventions. The population includes adults (\u226518 years) experiencing SMD. Standard review methods in terms of searches, screening, data extraction, and quality appraisal will be conducted. Narrative syntheses will be conducted. If feasible, a meta-analysis will be conducted for Review 1 and a thematic synthesis for Review 2. Evidence from the two reviews will then be synthesised together. Input from people with experience of SMD will be sought throughout to inform the reviews. An initial logic model will be iteratively refined during the review.<\/jats:p>","DOI":"10.3390\/ijerph182111554","type":"journal-article","created":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T17:59:38Z","timestamp":1635962378000},"page":"11554","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Investigating the Effectiveness and Acceptability of Oral Health and Related Health Behaviour Interventions in Adults with Severe and Multiple Disadvantage: Protocol for a Mixed-Methods Systematic Review"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4054-9300","authenticated-orcid":false,"given":"Laura J.","family":"McGowan","sequence":"first","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma C.","family":"Joyes","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7536-0658","authenticated-orcid":false,"given":"Emma A.","family":"Adams","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aishah","family":"Coyte","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Gavin","sequence":"additional","affiliation":[{"name":"Northumbria Healthcare, NHS Foundation Trust, Newcastle upon Tyne NE27 0QG, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2940-5197","authenticated-orcid":false,"given":"Catherine","family":"Richmond","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9512-1398","authenticated-orcid":false,"given":"Hosein","family":"Shabaninejad","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6396-3467","authenticated-orcid":false,"given":"Fiona","family":"Beyer","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Broadbridge","sequence":"additional","affiliation":[{"name":"Fulfilling Lives Newcastle\/Gateshead, Gateshead NE8 4DY, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1741-3699","authenticated-orcid":false,"given":"Kevin","family":"Dobson","sequence":"additional","affiliation":[{"name":"Fulfilling Lives Newcastle\/Gateshead, Gateshead NE8 4DY, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Landes","sequence":"additional","affiliation":[{"name":"Public Health England, London SE1 8UG, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Moffatt","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard G.","family":"Watt","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Public Health, University College London, London WC1E 7HB, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Falko F.","family":"Sniehotta","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8733-1253","authenticated-orcid":false,"given":"Ruth","family":"Freeman","sequence":"additional","affiliation":[{"name":"Dental Health Services Research Unit, University of Dundee, Dundee DD1 4HN, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha","family":"Paisi","sequence":"additional","affiliation":[{"name":"School of Nursing and Midwifery, University of Plymouth, Plymouth PL4 8AA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clare","family":"Bambra","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5808-0096","authenticated-orcid":false,"given":"Dawn","family":"Craig","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eileen","family":"Kaner","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheena E.","family":"Ramsay","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4AX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,11,3]]},"reference":[{"key":"ref_1","unstructured":"Bramley, G., Fitzpatrick, S., Edwards, J., Ford, D., Johnsen, S., Sosenko, F., and Watkins, D. (2015). Hard Edges. Mapping Severe and Multiple Disadvantage, Lankelly Chase Foundation."},{"key":"ref_2","unstructured":"(2021, March 09). Rough Sleeping\u2014Explore the Data. Available online: https:\/\/www.homeless.org.uk\/facts\/homelessness-in-numbers\/rough-sleeping\/rough-sleeping-explore-data."},{"key":"ref_3","unstructured":"Fitzpatrick, S., Pawson, H., Bramley, G., Wilcox, S., and Watts, B. (2017). The Homelessness Monitor: England 2017, Crisis."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1017\/S147474641100025X","article-title":"Multiple Exclusion Homelessness in the UK: Key Patterns and Intersections","volume":"10","author":"Fitzpatrick","year":"2011","journal-title":"Soc. Policy Soc."},{"key":"ref_5","unstructured":"(2014). The Unhealthy State of Homelessness, Homeless Link."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.1752-7325.2006.tb04082.x","article-title":"Oral health, related behaviors and oral health impacts among homeless adults","volume":"66","author":"Conte","year":"2006","journal-title":"J. Public Health Dent."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/j.1600-0528.2009.00516.x","article-title":"Oral health care needs and oral health-related quality of life (OHIP-14) in homeless people","volume":"38","author":"Daly","year":"2010","journal-title":"Community Dent. Oral Epidemiol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/sj.bdj.2014.594","article-title":"Oral health of adult prisoners and factors that impact on oral health","volume":"217","author":"Heidari","year":"2014","journal-title":"Br. Dent. J."},{"key":"ref_9","unstructured":"(2021, January 06). Healthy Mouths\u2014A Peer-Led Health Audit on the Oral Health of People Experiencing Homelessness. Available online: https:\/\/groundswell.org.uk\/wp-content\/uploads\/2017\/10\/Groundswell-Healthy-Mouths-Report-Final.pdf."},{"key":"ref_10","first-page":"711","article-title":"Strategies and approaches in oral disease prevention and health promotion","volume":"83","author":"Watt","year":"2005","journal-title":"Bull. World Health Organ."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/s41415-019-0472-7","article-title":"Understanding and tackling oral health inequalities in vulnerable adult populations: From the margins to the mainstream","volume":"227","author":"Watt","year":"2019","journal-title":"Br. Dent. J."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1353\/hpu.2016.0081","article-title":"Emergency Department Use for Dental Problems among Homeless Individuals: A Population-Based Cohort Study","volume":"27","author":"Figueiredo","year":"2016","journal-title":"J. Health Care Poor Underserved"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/sj.bdj.2016.56","article-title":"Evaluation of a community dental service for homeless and \u2019hard to reach\u2019 people","volume":"220","author":"Caton","year":"2016","journal-title":"Br. Dent. J."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/cdoe.12444","article-title":"Barriers and enablers to accessing dental services for people experiencing homelessness: A systematic review","volume":"47","author":"Paisi","year":"2019","journal-title":"Community Dent. Oral Epidemiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/idj.12626","article-title":"Dental Pain in Homeless Adults in Porto Alegre, Brazil","volume":"71","author":"Comassetto","year":"2021","journal-title":"Int. Dent. J."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1097\/XEB.0000000000000052","article-title":"A mixed-methods approach to systematic reviews","volume":"13","author":"Pearson","year":"2015","journal-title":"Int. J. Evid.-Based Health"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1136\/bmj.328.7446.1010","article-title":"Integrating qualitative research with trials in systematic reviews","volume":"328","author":"Thomas","year":"2004","journal-title":"BMJ"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"Moher","year":"2015","journal-title":"Syst. Rev."},{"key":"ref_19","unstructured":"McGowan, L.J., Joyes, E.C., Adams, E.A., Richmond, C., Shabaninejad, H., Beyer, F., Broadbridge, A., Dobson, K., Landes, D., and Moffat, S. (2020). Systematic review of oral health and related health behaviour interventions in adults with severe and multiple disadvantages. PROSPERO, CRD42020202416."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1002\/jrsm.32","article-title":"Using logic models to capture complexity in systematic reviews","volume":"2","author":"Anderson","year":"2011","journal-title":"Res. Synth. Methods"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1136\/jech-2014-204671","article-title":"\u2018Dark logic\u2019: Theorising the harmful consequences of public health interventions","volume":"69","author":"Bonell","year":"2015","journal-title":"J. Epidemiol. Community Health"},{"key":"ref_22","unstructured":"(2009). CRD\u2019s Guidance for Undertaking Reviews in Health Care, Centre for Reviews and Dissemination."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"409","DOI":"10.2217\/cer.12.46","article-title":"Involving the public in systematic reviews: A narrative review of organizational approaches and eight case examples","volume":"1","author":"Boote","year":"2012","journal-title":"J. Comp. Eff. Res."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1468-0009.2012.00665.x","article-title":"Uncovering the Benefits of Participatory Research: Implications of a Realist Review for Health Research and Practice","volume":"90","author":"Jagosh","year":"2012","journal-title":"Milbank Q."},{"key":"ref_25","first-page":"1","article-title":"Stakeholder involvement in systematic reviews: A protocol for a systematic review of methods, outcomes and effects","volume":"3","author":"Pollock","year":"2017","journal-title":"Res. Involv. Engag."},{"key":"ref_26","unstructured":"(2021, November 02). ETHOS\u2014European Typology on Homelessness and Housing Exclusion. Available online: https:\/\/www.feantsa.org\/en\/toolkit\/2005\/04\/01\/ethos-typology-on-homelessness-and-housing-exclusion#:~:text=FEANTSA%20has%20developed%20a%20European,for%20transnational%20exchanges%20on%20homelessness."},{"key":"ref_27","unstructured":"(2021, November 02). A Smarter Criminal Justice System that Makes the Revolving Door Avoidable and Escapable\u2014Strategy 2020\u20132024. Available online: http:\/\/www.revolving-doors.org.uk\/file\/2434\/download?token=75C9zzC1."},{"key":"ref_28","unstructured":"(2021, November 02). About Problematic Substance Use: Government of Canada. Available online: https:\/\/www.canada.ca\/en\/health-canada\/services\/substance-use\/about-problematic-substance-use.html."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/phr03010","article-title":"How effective are interventions at reducing socioeconomic inequalities in obesity among children and adults? Two systematic reviews","volume":"3","author":"Bambra","year":"2015","journal-title":"Public Health Res."},{"key":"ref_30","unstructured":"(2020, July 16). About Housing First. Available online: https:\/\/hfe.homeless.org.uk\/about-housing-first."},{"key":"ref_31","unstructured":"Covidence (2021, November 02). Covidence Systematic Review Software. Available online: www.covidence.org."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Moher, D., Liberati, A., Tetzlaff, J., Altman, D.G., and The, P.G. (2009). Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. PLoS Med., 6.","DOI":"10.1371\/journal.pmed.1000097"},{"key":"ref_33","unstructured":"Higgins, J.P.T., and Green, S. (2011). Cochrane Handbook for Systematic Reviews of Interventions, The Cochrane Collaboration. Version 5.1.0."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"g1687","DOI":"10.1136\/bmj.g1687","article-title":"Better reporting of interventions: Template for intervention description and replication (TIDieR) checklist and guide","volume":"348","author":"Hoffmann","year":"2014","journal-title":"BMJ Br. Med. J."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Deeks, J., Dinnes, J., D\u2019Amico, R., Sowden, A.J., Sakarovitch, C., Song, F., Petticrew, M., and Altman, D.G. (2003). Evaluating non-randomised intervention studies. Health Technol. Assess., 7.","DOI":"10.3310\/hta7270"},{"key":"ref_36","unstructured":"(2020, November 24). CASP Qualitative Checklist. Available online: https:\/\/casp-uk.net\/#!checklists\/cb36."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Drummond, M.S.M., Torrance, G., O\u2019Brien, B., and Stoddart G, G. (2005). Methods for the Economic Evaluation of Health Care Programmes, Oxford University Press. [2nd ed.].","DOI":"10.1093\/oso\/9780198529446.001.0001"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13643-017-0454-2","article-title":"Convergent and sequential synthesis designs: Implications for conducting and reporting systematic reviews of qualitative and quantitative evidence","volume":"6","author":"Hong","year":"2017","journal-title":"Syst. Rev."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1177\/1356389005059383","article-title":"An Emerging Framework for Including Different Types of Evidence in Systematic Reviews for Public Policy","volume":"11","author":"Oliver","year":"2005","journal-title":"Evaluation"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"l6890","DOI":"10.1136\/bmj.l6890","article-title":"Synthesis without meta-analysis (SWiM) in systematic reviews: Reporting guideline","volume":"368","author":"Campbell","year":"2020","journal-title":"BMJ"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"b2700","DOI":"10.1136\/bmj.b2700","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare in-terventions: Explanation and elaboration","volume":"339","author":"Liberati","year":"2009","journal-title":"BMJ"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.jclinepi.2015.09.001","article-title":"Extending the PRISMA statement to equity-focused systematic reviews (PRISMA-E 2012): Explanation and elaboration","volume":"70","author":"Welch","year":"2016","journal-title":"J. Clin. Epidemiol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/S0140-6736(17)31959-1","article-title":"What works in inclusion health: Overview of effective interventions for marginalised and excluded populations","volume":"391","author":"Luchenski","year":"2018","journal-title":"Lancet"},{"key":"ref_44","unstructured":"(2021, November 02). CCEMG and EPPI-Centre Cost Converter. Available online: https:\/\/eppi.ioe.ac.uk\/costconversion\/."},{"key":"ref_45","unstructured":"(2021, November 02). PSSRU Unit Costs of Health and Social Care 2020. Available online: https:\/\/www.pssru.ac.uk\/project-pages\/unit-costs\/unit-costs-2020\/."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"a1655","DOI":"10.1136\/bmj.a1655","article-title":"Developing and evaluating complex interventions: The new Medical Research Council guidance","volume":"337","author":"Craig","year":"2008","journal-title":"BMJ"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"j80","DOI":"10.1136\/bmj.j80","article-title":"Qualitative evidence synthesis to improve implementation of clinical guidelines","volume":"356","author":"Carroll","year":"2017","journal-title":"BMJ"},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Thomas, J., and Harden, A. (2008). Methods for the thematic synthesis of qualitative research in systematic reviews. BMC Med. Res. Methodol., 8.","DOI":"10.1186\/1471-2288-8-45"},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Tong, A., Flemming, K., McInnes, E., Oliver, S., and Craig, J. (2012). Enhancing transparency in reporting the synthesis of qualitative research: ENTREQ. BMC Med. Res. 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