{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T12:32:34Z","timestamp":1780921954461,"version":"3.54.1"},"reference-count":63,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T00:00:00Z","timestamp":1636416000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["408057478"],"award-info":[{"award-number":["408057478"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>While many authors have described the adverse health effects of poor air quality and meteorological extremes, there remain inconsistencies on a regional scale as well as uncertainty about the single and joint effects of atmospheric predictors. In this context, we investigated the short-term impacts of weather and air quality on moderate extreme cancer-related mortality events for the urban area of Augsburg, Southern Germany, during the period 2000\u20132017. First, single effects were uncovered by applying a case-crossover routine. The overall impact was assessed by performing a Mann\u2013Whitney U testing scheme. We then compared the results of this procedure to extreme noncancer-related mortality events. In a second step, we found periods with contemporaneous significant predictors and carried out an in-depth analysis of these joint-effect periods. We were interested in the atmospheric processes leading to the emergence of significant conditions. Hence, we applied the Principal Component Analysis to large-scale synoptic conditions during these periods. The results demonstrate a strong linkage between high-mortality events in cancer patients and significantly above-average levels of nitrogen dioxide (NO2) and particulate matter (PM2.5) during the late winter through spring period. These were mainly linked to northerly to easterly weak airflow under stable, high-pressure conditions. Especially in winter and spring, this can result in low temperatures and a ground-level increase and the accumulation of air pollution from heating and traffic as well as eastern lateral advection of polluted air. Additionally, above-average temperatures were shown to occur on the days before mortality events from mid-summer through fall, which was also caused by high-pressure conditions with weak wind flow and intense solar radiation. Our approach can be used to analyse medical data with epidemiological as well as climatological methods while providing a more vivid representation of the underlying atmospheric processes.<\/jats:p>","DOI":"10.3390\/ijerph182211737","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T12:46:23Z","timestamp":1636461983000},"page":"11737","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Associations between Weather, Air Quality and Moderate Extreme Cancer-Related Mortality Events in Augsburg, Southern Germany"],"prefix":"10.3390","volume":"18","author":[{"given":"Patrick","family":"Olschewski","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Augsburg, 86159 Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irena","family":"Kaspar-Ott","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Augsburg, 86159 Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Koller","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Augsburg, 86159 Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Schenkirsch","sequence":"additional","affiliation":[{"name":"Comprehensive Cancer Center, Augsburg University Medical Center, 86156 Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Trepel","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Augsburg, 86159 Augsburg, Germany"},{"name":"Comprehensive Cancer Center, Augsburg University Medical Center, 86156 Augsburg, Germany"},{"name":"Department of Internal Medicine II, Augsburg University Medical Center, 86156 Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6934-9468","authenticated-orcid":false,"given":"Elke","family":"Hertig","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Augsburg, 86159 Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,11,9]]},"reference":[{"key":"ref_1","unstructured":"Masson-Delmotte, V.P., Zhai, A., Pirani, S.L., Connors, C., P\u00e9an, S., Berger, N., Caud, Y., and Chen, L. 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