{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:40:02Z","timestamp":1760236802311,"version":"build-2065373602"},"reference-count":21,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T00:00:00Z","timestamp":1640649600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>(1) Background: Health disparities across the United States (U.S.) are increasing. Large variations in risk factors and health outcomes have been described among states from the U.S. (2) AIM. This study aims to describe health trends in morbidity, mortality, and risk factors from 1990 to 2019 in the State of Colorado. (3) Methods: We describe the measures of health loss for 286 causes of death, 369 diseases and injuries, and 87 risk factors for the state of Colorado from the Global Burden of Disease project estimates between 1990 to 2019. (4) Results: We found that 21,171 and 40,724 deaths were estimated in 1990 and 2019, respectively, in Colorado. The leading cause of death, in both sexes, in 1990 and 2019 was ischemic heart disease (IHD). The top leading disability-adjusted life years (DALY) diagnoses were IHD, followed by low back pain, chronic obstructive pulmonary disease, and opioid use disorder. In 2019, the top risk factors by DALYs in Colorado were smoking, drug use, high body mass index (BMI), alcohol use, high fasting plasma glucose, and high systolic blood pressure. (5) Conclusion: Non-communicable diseases and their related risk factors are the top leading causes of DALYs in Colorado. Findings support the need for policies to prevent non-communicable diseases, with special attention to musculoskeletal disorders and interventions to reduce tobacco, alcohol, and drug use.<\/jats:p>","DOI":"10.3390\/ijerph19010288","type":"journal-article","created":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T06:55:03Z","timestamp":1640674503000},"page":"288","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Colorado Burden of Disease, Injuries and Risk Factors, 1990\u20132019: A Sub-Analysis of the Global Burden of Disease Study"],"prefix":"10.3390","volume":"19","author":[{"given":"Jen","family":"Roux","sequence":"first","affiliation":[{"name":"Colorado School of Public Health, Colorado State University, 1601 Campus Delivery, Fort Collins, CO 80523, USA"},{"name":"Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5854-2484","authenticated-orcid":false,"given":"David","family":"Rojas-Rueda","sequence":"additional","affiliation":[{"name":"Colorado School of Public Health, Colorado State University, 1601 Campus Delivery, Fort Collins, CO 80523, USA"},{"name":"Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Weinstein, J.N., Geller, A., Negussie, Y., and Baciu, A. (2017). Communities in Action: Pathways to Health Equity, The National Academies Press.","DOI":"10.17226\/24624"},{"key":"ref_2","unstructured":"Murray, C.J.L., Lopez, A.D., World Health Organization, and Harvard School of Public Health (1996). The Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability from Diseases, Injuries, and Risk Factors i n1990 and Projected to 2020, Harvard School of Public Health."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1001\/jama.2018.0158","article-title":"The state of US health, 1990-2016: Burden of diseases, injuries, and risk factors among US states","volume":"319","author":"Murray","year":"2018","journal-title":"JAMA-J. Am. Med. Assoc."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1016\/S0140-6736(18)32207-4","article-title":"Changes in health in the countries of the UK and 150 English Local Authority areas 1990\u20132016: A systematic analysis for the Global Burden of Disease Study 2016","volume":"392","author":"Steel","year":"2018","journal-title":"Lancet"},{"key":"ref_5","unstructured":"US Census Bureau (2021, September 25). 2019 U.S. Population Estimates Continue to Show the Nation\u2019s Growth Is Slowing, Available online: https:\/\/www.census.gov\/newsroom\/press-releases\/2019\/popest-nation.html."},{"key":"ref_6","unstructured":"Colorado Department of Local Affairs (2020). Colorado\u2019s Population and Economic Trends, 2019."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/S0140-6736(20)30925-9","article-title":"Global burden of 369 diseases and injuries in 204 countries and territories, 1990\u20132019: A systematic analysis for the Global Burden of Disease Study 2019","volume":"396","author":"Vos","year":"2020","journal-title":"Lancet"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/S0140-6736(20)30752-2","article-title":"Global burden of 87 risk factors in 204 countries and territories, 1990\u20132019: A systematic analysis for the Global Burden of Disease Study 2019","volume":"396","author":"Murray","year":"2020","journal-title":"Lancet"},{"key":"ref_9","unstructured":"United States Census Bureau (2021, September 25). Map of the United States, Showing Census Divisions and Regions, The Statistical Abstract of the US, Available online: https:\/\/www.census.gov\/prod\/1\/gen\/95statab\/preface.pdf."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1016\/S0140-6736(18)32279-7","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017","volume":"392","author":"James","year":"2018","journal-title":"Lancet"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/S0140-6736(18)32203-7","article-title":"Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980\u20132017: A systematic analysis for the Global Burden of Disease Study 2017","volume":"392","author":"Roth","year":"2018","journal-title":"Lancet"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1016\/S0140-6736(19)30041-8","article-title":"Health effects of dietary risks in 195 countries, 1990\u20132017: A systematic analysis for the Global Burden of Disease Study 2017","volume":"393","author":"Afshin","year":"2019","journal-title":"Lancet"},{"key":"ref_13","unstructured":"Colorado Department of Public Health and the Environment (2021, May 06). Center for Health and Environmental Data|Department of Public Health & Environment, Available online: https:\/\/cdphe.colorado.gov\/center-for-health-and-environmental-data."},{"key":"ref_14","unstructured":"Colorado Department of Public Health and the Environment (2021, May 06). Workbook: CoHID Landing Page, Available online: https:\/\/cohealthviz.dphe.state.co.us\/t\/HealthInformaticsPublic\/views\/CoHIDLandingPage\/LandingPage?iframeSizedToWindow=true&:embed=y&:showAppBanner=false&:display_count=no&:showVizHome=no."},{"key":"ref_15","unstructured":"Colorado Health Foundation (2021, September 25). 2016 Colorado Health Report Card. Colorado Health Foundation. Available online: https:\/\/coloradohealth.org\/reports\/colorado-health-report-card."},{"key":"ref_16","unstructured":"(2021, September 25). U.S.-CDC (Centers for Disease Control and Prevention), Available online: https:\/\/www.cdc.gov\/opioids\/overdoseprevention\/opioid-use-disorder.html."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0140-6736(19)31893-8","article-title":"Primary prevention of ischaemic heart disease: Populations, individuals, and health professionals","volume":"394","author":"Gupta","year":"2019","journal-title":"Lancet"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1016\/S0140-6736(18)30489-6","article-title":"Prevention and treatment of low back pain: Evidence, challenges, and promising directions","volume":"391","author":"Foster","year":"2018","journal-title":"Lancet"},{"key":"ref_19","unstructured":"(2021, September 23). ODPHP (Office of Disease Prevention and Health Promotion), Available online: https:\/\/health.gov\/myhealthfinder\/topics\/everyday-healthy-living\/safety\/prevent-back-pain."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.drugpo.2019.03.003","article-title":"Acceptability of implementing community-based drug checking services for people who use drugs in three United States cities: Baltimore, Boston and Providence","volume":"68","author":"Sherman","year":"2019","journal-title":"Int. J. Drug Policy"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"7","DOI":"10.4103\/2008-7802.173797","article-title":"Health promotion methods for smoking prevention and cessation: A comprehensive review of effectiveness and the way forward","volume":"7","author":"Golechha","year":"2016","journal-title":"Int. J. Prev. Med."}],"container-title":["International Journal of Environmental Research and Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/1\/288\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:54:41Z","timestamp":1760169281000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1660-4601\/19\/1\/288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,28]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1]]}},"alternative-id":["ijerph19010288"],"URL":"https:\/\/doi.org\/10.3390\/ijerph19010288","relation":{},"ISSN":["1660-4601"],"issn-type":[{"type":"electronic","value":"1660-4601"}],"subject":[],"published":{"date-parts":[[2021,12,28]]}}}