{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T15:47:01Z","timestamp":1780933621610,"version":"3.54.1"},"reference-count":32,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T00:00:00Z","timestamp":1641945600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>(1) Background: Chronic diseases affect patients\u2019 quality of life. Age Macular Degeneration (AMD) is one of the most prevalent chronic ocular diseases. The study aims to measure the anxiety and quality of life related to vision in patients with AMD, as well as the relationship with other visual and demographic parameters. (2) Methods: Prospective cross-sectional study in AMD patients. Visual acuity (VA), contrast sensitivity (CS), line difference in the Colenbrander test, and the degree of pathology were measured. Other variables such as gender, age, and time from the diagnosis were also collected. Anxiety was measured with the Spielberger State-Trait Anxiety Inventory (STAI) and quality of life with the National Eye Institute Visual Function Questionnaire (NEI VFQ-25). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist was followed. (3) Results: Patients with higher punctuation in Trait STAI showed lower punctuation in NEI VFQ-25 questionnaire (Spearman coefficient \u22120.415; p = 0.001). The variables VA, CS, and age were correlated to the quality of life. The relationship between trait anxiety and subscales of NEI VFQ-25 was significant for all subscales (p &lt; 0.05), except for social functioning, peripheral vision, general vision, ocular pain, and driving. (4) Conclusions: AMD patients with higher levels of anxiety show a decrease in their quality of life. The quality of life of AMD patients depends on their VA and CS.<\/jats:p>","DOI":"10.3390\/ijerph19020820","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T09:10:36Z","timestamp":1641978636000},"page":"820","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Quality of Life and Anxiety in Age Macular Degeneration Patients: A Cross-Sectional Study"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8371-5527","authenticated-orcid":false,"given":"Daniel","family":"Caballe-Fontanet","sequence":"first","affiliation":[{"name":"Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1097-4581","authenticated-orcid":false,"given":"Cristina","family":"Alvarez-Peregrina","sequence":"additional","affiliation":[{"name":"Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neus","family":"Busquet-Duran","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Althaia Xarxa Assistencial Universit\u00e0ria de Manresa, 08243 Manresa, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4581-7028","authenticated-orcid":false,"given":"Eduard","family":"Pedemonte-Sarrias","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Althaia Xarxa Assistencial Universit\u00e0ria de Manresa, 08243 Manresa, Spain"},{"name":"Faculty of Medicine, University of Vic\u2014Central University of Catalonia (UVic\u2014UCC), 08500 Vic, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7558-4325","authenticated-orcid":false,"given":"Cristina","family":"Andreu-V\u00e1zquez","sequence":"additional","affiliation":[{"name":"Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2583-1789","authenticated-orcid":false,"given":"Miguel \u00c1ngel","family":"S\u00e1nchez-Tena","sequence":"additional","affiliation":[{"name":"ISEC LISBOA\u2014Instituto Superior de Educa\u00e7\u00e3o e Ci\u00eancias, 1750-179 Lisboa, Portugal"},{"name":"Department of Optometry and Vision, Faculty of Optics and Optometry, Universidad Complutense de Madrid, 28037 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,12]]},"reference":[{"key":"ref_1","unstructured":"National Eye Institute (2021, December 13). 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