{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T15:51:12Z","timestamp":1772725872702,"version":"3.50.1"},"reference-count":48,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2022,2,22]],"date-time":"2022-02-22T00:00:00Z","timestamp":1645488000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJERPH"],"abstract":"<jats:p>Mothers\u2019 knowledge about childhood asthma influences management practices and disease control, but validating knowledge\/practice questionnaires is difficult due to the lack of a gold standard. We hypothesized that Latent Class Analysis (LCA) could help identify underlying mother profiles with similar knowledge\/practices. A total of 438 mothers of asthmatic children answered a knowledge\/practice questionnaire. Using answers to the knowledge\/practice questionnaire as manifest variables, LCA identified two classes: Class 1, \u201cpoor knowledge\u201d (33%); Class 2, \u201cgood knowledge\u201d (67%). Classification accuracy was 0.96. Mothers in Class 2 were more likely to be aware of asthma-worsening factors and indicators of attacks. Mothers in Class 1 were more likely to prevent exposure to tobacco smoke (91.1% vs. 78.8%, p = 0.005). For attacks, mothers in Class 2 were more likely to go to the emergency department and follow the asthma action plan. Mothers in Class 2 more frequently had a high education level (79.5% vs. 65.2%, p = 0.004). Children in Class 2 more frequently had fully controlled asthma (36.7% vs. 25.9%, p = 0.015) and hospitalizations for attacks in the previous 12 months (24.2% vs. 10.7%, p = 0.003). LCA can help discover underlying mother profiles and plan targeted educational interventions.<\/jats:p>","DOI":"10.3390\/ijerph19052539","type":"journal-article","created":{"date-parts":[[2022,2,22]],"date-time":"2022-02-22T22:34:30Z","timestamp":1645569270000},"page":"2539","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Asthma-Related Knowledge and Practices among Mothers of Asthmatic Children: A Latent Class Analysis"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5378-5505","authenticated-orcid":false,"given":"Salvatore","family":"Fasola","sequence":"first","affiliation":[{"name":"Institute of Translational Pharmacology, National Research Council, 90146 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Velia","family":"Malizia","sequence":"additional","affiliation":[{"name":"Institute of Translational Pharmacology, National Research Council, 90146 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuliana","family":"Ferrante","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Division, University of Verona, 37134 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1773-6482","authenticated-orcid":false,"given":"Amelia","family":"Licari","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Fondazione IRCCS Policlinico San Matteo, University of Pavia, 27100 Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Montalbano","sequence":"additional","affiliation":[{"name":"Institute of Translational Pharmacology, National Research Council, 90146 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4305-3981","authenticated-orcid":false,"given":"Giovanna","family":"Cilluffo","sequence":"additional","affiliation":[{"name":"Department of Earth and Marine Sciences, University of Palermo, 90123 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8026-0715","authenticated-orcid":false,"given":"Stefania","family":"La Grutta","sequence":"additional","affiliation":[{"name":"Institute of Translational Pharmacology, National Research Council, 90146 Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,2,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"170","DOI":"10.3389\/fped.2018.00170","article-title":"Difficult vs. Severe Asthma: Definition and Limits of Asthma Control in the Pediatric Population","volume":"6","author":"Licari","year":"2018","journal-title":"Front. 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